M.D. Anderson Cancer Center: Glioma trials

The registry lists 25 Glioma studies with M.D. Anderson Cancer Center as lead sponsor. 7 are open to participants now and 4 have results posted.

Early Phase 1 1Phase 1 12Phase 2 6Phase 3 1No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationRecruitingNCT07076498Phase 1
• Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated GliomasRecruitingNCT05804227Early Phase 1
• Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade GliomaRecruitingNCT04771806
• MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated GliomasRecruitingNCT04373720Not applicable
• HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
• MSC-DNX-2401 in Treating Patients With Recurrent High-Grade GliomaRecruitingNCT03896568Phase 1
• Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy ProgramRecruitingNCT01772771
• Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With GlioblastomaCompletedNCT02661282Phase 1/2Results posted
• Lacosamide in Preventing Seizures in Participants With Malignant GliomaTerminatedNCT01432171Not applicableResults posted
• 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma PatientsCompletedNCT00504660Phase 2Results posted
• Thalidomide and Temozolomide or Camptothecin-11 (CPT-11) in Patients With GliomasCompletedNCT00412542Phase 2Results posted
• Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma PatientsActive, not recruitingNCT05511324Not applicable
• Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain CancerWithdrawnNCT04521946Phase 1
• Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation TherapyActive, not recruitingNCT04186832Not applicable
• Resting-State Functional MRI in Glioma Patients Before and After SurgeryCompletedNCT03964909Not applicable
• Mind-Body Intervention in Glioma CouplesActive, not recruitingNCT03244995Not applicable
• Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their PartnersActive, not recruitingNCT02481349Not applicable
• Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine GliomaCompletedNCT02420613Phase 1
• STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the BrainCompletedNCT01904123Phase 1
• Phase I/II Cabazitaxel for Recurrent Malignant GliomaWithdrawnNCT01740570Phase 1/2
• Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)CompletedNCT01469247Phase 1/2
• Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase ITerminatedNCT00671801Phase 1
• Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant GliomasCompletedNCT00038441Phase 1/2
• Study of Vioxx and Radiation Therapy for Brainstem GliomaTerminatedNCT00038389Phase 1
• Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant GliomasWithdrawnNCT00003564Phase 3