Johnson & Johnson: Bipolar Disorder trials

The registry lists 39 Bipolar Disorder studies with Johnson & Johnson as lead sponsor. 2 are open to participants now and 9 have results posted.

Phase 1 5Phase 2 1Phase 3 28Phase 4 2No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric PatientsRecruitingNCT06372964Phase 3
• Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum DisorderRecruitingNCT06229210Phase 3
• A Study of JNJ-55308942 in the Treatment of Bipolar DepressionCompletedNCT05328297Phase 2Results posted
• Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive DisorderCompletedNCT04285515Phase 3Results posted
• Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted GloballyCompletedNCT03249376Phase 3Results posted
• Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar DepressionCompletedNCT02600507Phase 3Results posted
• Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar DepressionCompletedNCT02600494Phase 3Results posted
• A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in ChildrenCompletedNCT01050582Phase 4Results posted
• A Study to Evaluate the Effectiveness and Safety of Extended-Release (ER) Paliperidone Compared With Placebo in Delaying the Recurrence of Symptoms in Bipolar I DisorderCompletedNCT00490971Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Risperidone for the Prevention of Mood Episodes in the Treatment of Patients With Bipolar I DisorderCompletedNCT00391222Phase 3Results posted
• A Study of the Safety and Efficacy of Injectable Risperidone in the Prevention of Bipolar Mood EpisodesCompletedNCT00132678Phase 3Results posted
• Study of Lumateperone in the Treatment of Patients With Bipolar ManiaCompletedNCT06462612Phase 3
• Study of Lumateperone in the Acute Treatment of Patients With Bipolar ManiaCompletedNCT06462586Phase 3
• A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar DisorderCompletedNCT03017781
• Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric ParticipantsCompletedNCT02087579Phase 1
• Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health OrganizationsCompletedNCT01181960
• A Drug Interaction Study of Valproic Acid and Paliperidone Extended-Release (ER) in Patients With Schizophrenia, Bipolar I Disorder, or Schizoaffective DisorderCompletedNCT01094249Phase 1
• A Pharmacokinetic Study of Risperidone and Topiramate Administered Alone and in Combination in Patients With Bipolar Disorder or Schizoaffective DisordersCompletedNCT00986336Phase 1
• A Pharmacokinetic Study of Lithium Before and During Topiramate Dosing in Bipolar Disorder PatientsCompletedNCT00986128Phase 1
• A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I DisorderCompletedNCT00892125Phase 1
• A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I DisorderCompletedNCT00309699Phase 3
• A Study to Evaluate the Efficacy and Safety of Adjustable Doses of Extended-release (ER) Paliperidone Compared With Placebo, in Combination With Lithium or Valproate, to Treat Manic and Mixed Episodes in Patients With Bipolar I DisorderCompletedNCT00309686Phase 3
• A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I DisorderCompletedNCT00299715Phase 3
• ADH.E.R.E.: Therapeutic ADHerence and Treatment Strategies: A Mental Health RegistryCompletedNCT00264069
• A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Manic Episodes Associated With Bipolar I DisorderCompletedNCT00257075Phase 3
• A Study of the Effectiveness and Safety of Risperidone Compared With Placebo in the Treatment of Manic Episodes Associated With Bipolar I Disorder, and the Maintenance of Anti-manic Effectiveness of Risperidone Compared With HaloperidolCompletedNCT00253162Phase 3
• A Study of the Effectiveness and Safety of Risperidone as add-on Therapy to Mood Stabilizers in the Treatment of Manic Episodes Associated With Bipolar DisorderCompletedNCT00253149Phase 3
• A Study of the Effectiveness and Safety of Risperidone Versus Placebo as add-on Therapy to Mood Stabilizers, in the Treatment of Manic Episodes Associated With Bipolar Disorder.CompletedNCT00250367Phase 3
• A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Manic or Mixed Episodes Associated With Bipolar I DisorderCompletedNCT00249236Phase 3
• A Randomized, Open-label Trial of Long-acting Injectable Risperidone Versus Oral Antipsychotic Medication in Patients With Bipolar DisorderCompletedNCT00246246Phase 3
• A Study of the Effectiveness and Safety of Topiramate in the Treatment of Patients With Bipolar DisorderCompletedNCT00240721Phase 3
• Topiramate Versus Placebo as add-on Treatment in Patients With Bipolar Disorder in the Outpatient SettingCompletedNCT00237289Phase 3
• The Safety and Efficacy of Risperidone as Adjunctive Therapy to Mood Stabilizers in the Long-term Treatment of Bipolar ManiaCompletedNCT00216554Phase 4
• Study Measuring Differences in Cognition Due to Sedative Effects of Risperidone and Quetiapine in Stable Bipolar I OutpatientsCompletedNCT00097032Phase 3
• A Study of Effectiveness and Safety of Risperdal CONSTA Added to Usual Treatment in Patients With Bipolar Disorder Who Have Frequent Mood Episodes.CompletedNCT00094926Phase 3
• Study to Determine the Effectiveness of Risperidone in Bipolar Disorder in Children and AdolescentsCompletedNCT00076115Phase 3
• A Study on the Safety and Efficacy of Topiramate in the Treatment of Patients With Bipolar I DisorderCompletedNCT00037674Phase 3
• A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I DisorderCompletedNCT00035802Phase 3
• A Study on the Safety and Efficacy of Topiramate in the Treatment of Patients With Bipolar I DisorderCompletedNCT00035230Phase 3