Johns Hopkins University: Multiple Sclerosis trials

The registry lists 27 Multiple Sclerosis studies with Johns Hopkins University as lead sponsor. 4 are open to participants now and 11 have results posted.

Phase 1 6Phase 2 6Phase 3 3Phase 4 3No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple SclerosisRecruitingNCT07497399Phase 2
• Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple SclerosisRecruitingNCT07389590Phase 4
• Solriamfetol for the Treatment of Multiple Sclerosis FatigueRecruitingNCT06170970Phase 2
• Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking OfatumumabEnrolling by invitationNCT06167642
• Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple SclerosisTerminatedNCT04767698Phase 2Results posted
• Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple SclerosisCompletedNCT04261790Phase 4Results posted
• Short-term B-cell Depletion in Relapsing Multiple SclerosisCompletedNCT03853746Phase 4Results posted
• Ketamine for Treatment of MS FatigueCompletedNCT03500289Phase 1/2Results posted
• A Trial of Bile Acid Supplementation in Patients With Multiple SclerosisCompletedNCT03423121Phase 1/2Results posted
• Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple SclerosisCompletedNCT03185065Phase 3Results posted
• Intranasal Insulin for Improving Cognitive Function in Multiple SclerosisCompletedNCT02988401Phase 1/2Results posted
• A Pragmatic Trial of Dietary Programs in People With Multiple Sclerosis (MS)CompletedNCT02846558Not applicableResults posted
• tDCS and Cognition in Adults With Multiple Sclerosis or EncephalitisCompletedNCT02538094Not applicableResults posted
• Pharmacokinetics of Vitamin D in Multiple Sclerosis and in HealthCompletedNCT01667796Not applicableResults posted
• Vitamin D Supplementation in Multiple SclerosisCompletedNCT01490502Phase 3Results posted
• Trial of eHealth Wellness Behavioral Interventions and Patient-reported OutcomesCompletedNCT05442112Not applicable
• iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple SclerosisCompletedNCT04147052Not applicable
• Bright Light Therapy for Sleep Disturbance in People With Multiple SclerosisCompletedNCT04054050Not applicable
• Emotion Regulation Skills Training for Individuals With MS and Their Support PartnersCompletedNCT03934489Not applicable
• Ocrelizumab Effects on the Metabolome in MSCompletedNCT03873389
• A Pilot Study of Intermittent Calorie Restriction in Multiple SclerosisCompletedNCT02647502Not applicable
• Open-label Study of Liothyronine in MSCompletedNCT02506751Phase 1
• The Use of Technology to Improve MS Clinical Trials and Patient CareCompletedNCT02454907Not applicable
• A Phase 1 Trial of Intrathecal Rituximab for Progressive Multiple Sclerosis PatientsCompletedNCT02253264Phase 1
• Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple SclerosisCompletedNCT01647321Not applicable
• Using Optical Coherence Tomography (OCT) to Evaluate the Efficacy and Safety of PEGylated Interferon Beta-1a (BIIB017) in Patients With Relapsing Multiple SclerosisWithdrawnNCT01337427Phase 3
• Safety and Immunologic Effect of Low Dose Versus High Dose Vitamin D3 in Multiple SclerosisCompletedNCT01024777Phase 1