InSightec: Parkinson Disease trials

The registry lists 19 Parkinson Disease studies with InSightec as lead sponsor. 3 are open to participants now and 3 have results posted.

No phase 19(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Unilateral and Staged Bilateral Pallidothalamic Tractotomy Using Exablate MRgFUS in Advanced Parkinson's Disease.Not yet recruitingNCT07764874Not applicable
• A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor ComplicationsRecruitingNCT05539196
• A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's DiseaseRecruitingNCT04991831
• ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's DiseaseCompletedNCT02263885Not applicableResults posted
• ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's DiseaseCompletedNCT02246374Not applicableResults posted
• ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Parkinson's DiseaseCompletedNCT01772693Not applicableResults posted
• A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's DiseaseActive, not recruitingNCT06584383Not applicable
• MR-guided Focused Ultrasound Plus GCaseActive, not recruitingNCT05565443Not applicable
• A Clinical Trial for the Safety and Effect of MRGuided FUS Subthalamotomy for Medication Refractory Parkinson's DiseaseCompletedNCT04744493Not applicable
• Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)Active, not recruitingNCT04728295Not applicable
• Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's DiseaseCompletedNCT04370665Not applicable
• Safety and Initial Effectiveness of Transcranial MR Guided Focused Ultrasound for the Treatment of Parkinson's DiseaseCompletedNCT04002596Not applicable
• A Feasibility Study on the Safety and Preliminary Efficacy of Bilateral Subthalamotomy Using MRgFUS for Treatment of PDCompletedNCT03964272Not applicable
• A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease DementiaCompletedNCT03608553Not applicable
• A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor FeaturesCompletedNCT03454425Not applicable
• ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Parkinson's DiseaseActive, not recruitingNCT03319485Not applicable
• Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:Active, not recruitingNCT03100474
• ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's DiseaseCompletedNCT02347254Not applicable
• ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement DisordersActive, not recruitingNCT02252380Not applicable