H. Lee Moffitt Cancer Center and Research Institute: Graft vs Host Disease trials

The registry lists 13 Graft vs Host Disease studies with H. Lee Moffitt Cancer Center and Research Institute as lead sponsor. 0 are open to participants now and 9 have results posted.

Phase 1 5Phase 2 10No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune SuppressionCompletedNCT02891603Phase 1/2Results posted
• Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) PreventionCompletedNCT02588339Phase 2Results posted
• In Vivo Treg Expansion and Graft-Versus-Host Disease ProphylaxisCompletedNCT01927120Phase 2Results posted
• Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host DiseaseCompletedNCT01713400Phase 2Results posted
• Ofatumumab as Primary Therapy of Chronic Graft Versus Host DiseaseCompletedNCT01680965Phase 1/2Results posted
• Histone Deacetylase Inhibitor LBH589 in Addition to Corticosteroids in Patients With Acute Graft Versus Host Disease (GVHD)CompletedNCT01111526Phase 1/2Results posted
• Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell TransplantationCompletedNCT00803010Phase 2Results posted
• Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell TransplantationTerminatedNCT00720629Phase 2Results posted
• Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTXCompletedNCT00360685Not applicableResults posted
• CD40-L Blockade for Prevention of Acute Graft-Versus-Host DiseaseCompletedNCT03605927Phase 1
• Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host DiseaseCompletedNCT01795573Phase 1
• Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection of Previous Bone Marrow TransplantTerminatedNCT00005852Phase 2
• Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow TransplantationTerminatedNCT00005641Phase 2