Gustave Roussy, Cancer Campus, Grand Paris: all 244 studies

Page 1 of 3. Open to participants first (66), then studies with results posted, then the rest; newest registration first within each.

• Fight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to RelapseRecruitingNCT07871864Phase 3
• Evaluation of the Efficacy and Safety of Neoadjuvant Therapy in Patients With Surgically Resectable Pancreatic Adenocarcinoma.Not yet recruitingNCT07808567Phase 2
• Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.Not yet recruitingNCT07802847Phase 4
• Doxorubicin With or Without DT-7012 in Advanced Soft Tissue SarcomaNot yet recruitingNCT07802652Phase 2
• Preliminary Clinical Feasibility Study of a Medical Device Enabling Brain Access Using Microbubble-Enhanced SonicationNot yet recruitingNCT07754006Phase 1
• KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal CancerNot yet recruitingNCT07622017Phase 2
• Adjuvant Trial in Pancreatic Neuroendocrine TumorsNot yet recruitingNCT07591493Phase 3
• Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate CancerNot yet recruitingNCT07591467Phase 3
• Helping Young People With Testicular Cancer Using Virtual and Extended RealityNot yet recruitingNCT07571499Not applicable
• Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic DiseasesNot yet recruitingNCT07544225Phase 1
• Cohort of Patients With Chronic Myelomonocytic LeukemiaRecruitingNCT07512882
• Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/ResistanceRecruitingNCT07483983Phase 2
• Survival Without Persistent Limiting Toxicity: Real Life Prospective Cohort of Advanced Neuroendocrine TumorNot yet recruitingNCT07471425
• Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of CancerRecruitingNCT07436312Not applicable
• Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial LesionsNot yet recruitingNCT07431502Phase 3
• Efficacy and Safety of the Valemetostat in Patients With Selected Solid Tumors.RecruitingNCT07303387Phase 2
• A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast CancerRecruitingNCT07159451Phase 2
• A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive InductionNot yet recruitingNCT07082452Phase 3
• Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance (UNLOCK TARLATAMAB)RecruitingNCT07016230Phase 2
• Oral Pooled Fecal Microbiotherapy (MaaT033) Concomitant to Cemiplimab Versus Best Investigator's Choice in Patients With Resistance to Treatment Due to Antibiotics Uptake With Advanced Non-small Cell Lung CancerRecruitingNCT07001618Phase 2
• Analysis of Risk Factors for Hearing Loss in Survivors of Cancer Occurred During Childhood, Adolescence or Young AdulthoodNot yet recruitingNCT06957132Not applicable
• Cabozantinib and Nivolumab Among Older Patients With Renal Cell CarcinomaRecruitingNCT06934057Phase 4
• Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk IndividualsRecruitingNCT06907095Not applicable
• First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients.RecruitingNCT06840782Phase 3
• Study Assessing the Efficacy and Safety of cANnabidiol Oral Solution for Joint Pain of Adjuvant enDOcrine theRApy in Patients With Early Breast CancerNot yet recruitingNCT06787118Phase 3
• A Study to Determine the Efficacy of a Digital Self-management Support Tool to Improve the Quality of Life During Adjuvant HOrmonal Therapy for Patients With Early Breast CancerRecruitingNCT06781996Phase 3
• Randomized Phase III Trial Testing Maintenance Olaparib Versus Observation After Adjuvant Chemoradiation for p53abn Endometrial CancerRecruitingNCT06712472Phase 3
• A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast CancerRecruitingNCT06508216Phase 1/2
• STEpwise Research Program to Promote INGeniouS ONline Supportive Solutions in the Relief of Cancer-related FatigueRecruitingNCT06505590Not applicable
• PROACT is a Prospective Master Protocol for a Cohort Study Focused on Evaluating the Implementation of Integrated Proactive Supportive Care Pathways at Gustave RoussyRecruitingNCT06479057
• Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid CancerRecruitingNCT06439888Phase 1/2
• Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal AdenocarcinomaRecruitingNCT06402864Phase 3
• CARE1 Pragmatic Clinical TrialRecruitingNCT06364631Phase 3
• tislelizUMaB in canceR Patients With molEcuLar residuaL DiseaseRecruitingNCT06332274Phase 3
• Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXdRecruitingNCT06298084Phase 1/2
• Preoperative Radiotherapy And ASTX660 in Rectum CancerRecruitingNCT05912075Phase 1
• Engineering Immune Organoids to Study Pediatric CancerRecruitingNCT05890781Not applicable
• Morbidity, Long-term Side Effects and Quality of Life in Germ-cell Tumor Long Survivors Treated with High-dose Chemotherapy and Autologous Stem Cell TransplantRecruitingNCT05889585Not applicable
• Thromboprophylaxis in Good and Intermediate Prognosis Advanced Germ Cell TumorsRecruitingNCT05874063Phase 3
• Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell TumorsRecruitingNCT05705687Not applicable
• Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority StudyRecruitingNCT05692999Phase 3
• MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2RecruitingNCT05691608Not applicable
• Sotorasib in Previously Treated Locally Advanced or Metastatic NSCLC Subjects With Mutated KRAS p.G12CRecruitingNCT05631249Phase 2
• An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic TumorsRecruitingNCT05481502Not applicable
• Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0RecruitingNCT05476939Phase 3
• Implementing Precision Medicine in cOmmunity HospiTALsRecruitingNCT05283044Not applicable
• Prospective Multicenter Study Evaluating Feasibility and Efficacy of Tumor Organoid-based Precision Medicine in Patients With Advanced Refractory CancersRecruitingNCT05267912Not applicable
• Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast CancerRecruitingNCT04965766Phase 2
• Gustave Roussy Cancer ProfilingRecruitingNCT04932525Not applicable
• Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT SurgeryRecruitingNCT04842162Phase 2
• Hepatic Intra-Arterial Administration of Ipilimumab in Combination With Intra-venous Nivolumab for Advanced Hepatocellular CarcinomaRecruitingNCT04823403Phase 1
• Discovery of Microbiome-based Biomarkers for Patients With Cancer Using Metagenomic ApproachRecruitingNCT04567446
• Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young AdultsRecruitingNCT04477681
• Pediatric Hepatic TumorsRecruitingNCT04274868
• IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell CarcinomasRecruitingNCT04224389
• High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)RecruitingNCT04221035Phase 3
• Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young AdultsRecruitingNCT03983369Phase 3
• Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate CancerRecruitingNCT03819101Phase 3
• Neurocognitive Risks in Children With Solid TumorsRecruitingNCT03609112
• Study of Coronary Calcium Score as a Marker of Post-radiation Vascular Dysplasia in Adults Treated During Childhood for Cancer With Mediastinal IrradiationRecruitingNCT03604627Not applicable
• Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell CarcinomaRecruitingNCT03406247Phase 2
• Prognostic and Predictive Biomarkers in Ovarian CancersRecruitingNCT03010124Not applicable
• European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory TumorsRecruitingNCT02813135Phase 1/2
• Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples BankRecruitingNCT02666625
• Sequential Analysis in Patients With an HemopathyRecruitingNCT02260739Not applicable
• Therapeutic Strategy Guided by PET-TDM for Patients With SeminomaRecruitingNCT01887340Phase 2
• Study on the Effectiveness and Comfort of Innovative Solutions for the Internal Transport of Patients in Wheelchairs in a Hospital SettingCompletedNCT06902883Phase 2
• Prospective Analysis of Circulating Nucleosomes in Patients Receiving a First Line Treatment for a Non-Hodgkin LymphomaActive, not recruitingNCT06813573Not applicable
• Targeting PD-L1 and TIGIT in Tumors With Tertiary Lymphoid StructuresWithdrawnNCT06713798Phase 2
• Study Evaluating Pembrolizumab +/- Olaparib in TLS Positive Selected Resectable STS Followed by Adjuvant PembrolizumabWithdrawnNCT06116578Phase 2
• Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal CancerCompletedNCT06007092Phase 1/2
• Optimization of an Online Stepwise Therapeutic Device Based on a Cognitive-behavioral Approach for Cancer Patients With InsomniaCompletedNCT05977062Not applicable
• Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing SarcomaActive, not recruitingNCT05830084Phase 1
• Clinical Investigation Evaluating Safety and Efficacy of Selective Intra-arterial 166Holmium Radiation Therapy in Combination With Atezolizumab and Bevacizumab for Non Resectable Hepatocellular CarcinomaTerminatedNCT05705791Not applicable
• Short-term Pre-OPerative Durvalumab (MEDI 4736) in Early Small Triple Negative Breast Cancer Patients (POP-Durva)Active, not recruitingNCT05215106Phase 2
• Impact of Neoadjuvant Immunotherapy in Early Stage Breast Cancer Before Standard TherapyTerminatedNCT05180006Phase 2
• A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell CarcinomaTerminatedNCT05119010Not applicable
• Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or AdolescenceCompletedNCT05071001Not applicable
• Datopotamab Deruxtecan (Dato-DXd, DS-1062a) in Advanced and/or Unresectable Non-Small Cell Lung CancerActive, not recruitingNCT04940325Phase 2
• USE OF 18FDG PET-CT TO PREDICT THE RESPONSE OF MANDIBULAR OSTEORADIONECROSIS TO THE PENTOCLO PROTOCOL WITH DOCUMENTED ANTIBIOTHERAPYStatus unknownNCT04826445
• Pasireotide to Reduce Clinically Relevant Digestive Leakage After Complete Cytoreductive Surgery (CRS) Plus Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) for Peritoneal CarcinomatosisTerminatedNCT04826432Phase 2
• Safety and Efficacy of AsiDNATM, a DNA Repair Inhibitor, Administered Intravenously in Addition to PARP Inhibitors in Patients With Relapsed Platinum Sensitive Ovarian Cancer Already Treated With PARP Inhibitors Since at Least 6 MonthsTerminatedNCT04826198Phase 1/2
• Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and DostarlimabTerminatedNCT04779151Phase 2
• Classical Monocyte Kinetics in Chronic Myelomonocytic LeukemiaCompletedNCT04775121Not applicable
• Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory PathwaysStatus unknownNCT04349293Not applicable
• Epidemiology of SARS-CoV-2 and Mortality to Covid19 Disease in French Cancer PatientsStatus unknownNCT04341207Phase 2
• Motivating to Exercise and Diet, and Educating to Healthy Behaviors After Breast CancerCompletedNCT04304924Not applicable
• Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid TumorsTerminatedNCT04276376Phase 2
• Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced CancersTerminatedNCT04270864Phase 1
• Nivolumab in Combination With Temozolomide and Radiotherapy in Children and Adolescents With Newly Diagnosed High-grade GliomaCompletedNCT04267146Phase 1/2
• Predictive Markers of Immune-related Adverse Events in Patients Treated With Immune Stimulatory DrugsActive, not recruitingNCT03984318Not applicable
• Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid TumorsWithdrawnNCT03982173Phase 2
• Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and ChemotherapyWithdrawnNCT03982121Phase 1
• Video-Based Cognitive Behavioral Therapy for Insomnia in Adults Cancer Patients and SurvivorsCompletedNCT03981666Not applicable
• Nivolumab for Pediatric and Adult Relapsing/Refractory ALK+, for Evaluation of Response in Patients With Progressive Disease (Cohort 1) or as Consolidative Immunotherapy in Patients in Complete Remission After Relapse (Cohort 2)Active, not recruitingNCT03703050Phase 2
• Study of a Simplified Geriatric Evaluation Performed by Oncologists Prior to Cancer Treatment by Radiotherapy or Chemotherapy in Subjects Aged 70 Years or Older With Inoperable Squamous Cell Cancer of the Head and NeckStatus unknownNCT03614936
• Mechanistic and Molecular Study of the Process of Metastatic Dissemination in Colorectal CancerStatus unknownNCT03613194Not applicable
• Trial Assessing the Inhibitor of Programmed Cell Death Ligand 1 (PD-L1) Immune Checkpoint AtezolizumabCompletedNCT03612791Phase 2
• Multiparametric PET-MRI Integration for a New Approach to Tumor Heterogeneity in Non-Small Cell Lung Cancer (NSCLC): Pilot StudyTerminatedNCT03606070Not applicable
• Evaluation of HPV OncoTect ™ for the Etiological Diagnosis of HPV-induced Oropharyngeal CancersStatus unknownNCT03604588Not applicable

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