GlaxoSmithKline: Urinary Tract Infections trials

The registry lists 14 Urinary Tract Infections studies with GlaxoSmithKline as lead sponsor. 4 are open to participants now and 9 have results posted.

Phase 1 6Phase 2 3Phase 3 4Phase 4 1No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Prospective Registry of Exposure to Gepotidacin (PREG)Not yet recruitingNCT07850141
• A Study to Evaluate Gepotidacin Exposure in Breast Milk of Healthy Lactating WomenRecruitingNCT07645235Phase 1
• A Study in Pediatric Participants Aged ≥2 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis AntibioticsNot yet recruitingNCT07371429Phase 1
• A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of AgeRecruitingNCT06702449Phase 1/2
• A Study in Adolescent and Adult Female Participants to Evaluate Clinical Symptom Improvement and the Safety of Gepotidacin During Treatment of Uncomplicated Urinary Tract Infections (Acute Cystitis)CompletedNCT06597344Phase 3Results posted
• A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)CompletedNCT05630833Phase 3Results posted
• Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract InfectionsCompletedNCT05138822Phase 1Results posted
• Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.CompletedNCT04488770Phase 1Results posted
• Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)CompletedNCT04187144Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)CompletedNCT04020341Phase 3Results posted
• Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)CompletedNCT03568942Phase 2Results posted
• A Bioequivalence Study of Cefadroxil Film Coated Tablets After A Single Oral Dose Administration to Healthy SubjectsCompletedNCT02446496Phase 4Results posted
• GSK2251052 in Complicated Urinary Tract InfectionTerminatedNCT01381549Phase 2Results posted
• Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 YearsCompletedNCT05760261Phase 1