GlaxoSmithKline: Asthma trials

The registry lists 261 Asthma studies with GlaxoSmithKline as lead sponsor. 7 are open to participants now and 132 have results posted.

Phase 1 63Phase 2 59Phase 3 61Phase 4 53No phase 26(a study in two phases counts in both)

Studies

Page 3 of 3. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Drug Interaction Study With Fluticasone Furoate/GW642444 Inhalation Powder and KetoconazoleCompletedNCT01165125Phase 1
• Oral GW766944 (Oral CCR3 Antagonist)CompletedNCT01160224Phase 2
• A Blinded, Dose Ascending Study to Assess the Pharmacokinetics, Safety and Tollerability of Repeat Inhaled Doses of Nebulised GW870086X in Healthy Adult Male Volunteers.CompletedNCT01160003Phase 1
• Intravenous Microdose Pharmacokinetic (PK) Study With [14C]-GSK2239633CompletedNCT01086462Phase 1
• Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese SubjectsCompletedNCT01000597Phase 1
• A Study of GW685698X in Healthy Japanese Male SubjectsCompletedNCT00972673Phase 1
• GSK2190915 Safety and Pharmacokinetic Study in Healthy Japanese SubjectsCompletedNCT00955383Phase 1
• Study of Salmeterol (SN408D) for Adult AsthmaCompletedNCT00950794Phase 4
• A Study to Evaluate the Effect of Repeat Doses of GW870086X in Mild to Moderate AsthmaticsCompletedNCT00945932Phase 2
• Advair Pediatric Once-DailyCompletedNCT00920959Phase 3
• GSK BHR Study (Sont)CompletedNCT00920543Phase 4
• A Follow-up Survey to Compare Stable Dosing (SERETIDE) With SYMBICORT, SMART, Maintenance and Reliever Therapy in One Inhaler in Moderate and Severe Asthmatics.CompletedNCT00858286Phase 4
• Study to Evaluate GSK2190915 in Subjects With Mild AsthmaCompletedNCT00812773Phase 2
• Study in Mild Asthmatic PatientsCompletedNCT00748306Phase 2
• Comparing Two Respiratory Drugs in Combination and Separately From a Novel Inhaler Device in Healthy Japanese SubjectsCompletedNCT00625196Phase 1
• Clinical Endpoint Trial Investigating Once Daily and Bronchodilator DosingCompletedNCT00549744Phase 2
• A Randomized Study Evaluating Steroid Hormone Levels, Safety And Tolerability Of GW870086X In Healthy VolunteersCompletedNCT00549497Phase 1
• Comparing Two Respiratory Drugs When Used In Combination And Separately From A Novel Inhaler Device In Healthy SubjectsCompletedNCT00538057Phase 1
• Repeat Dose GW685698X With Magnesium Stearate, Excipient Bridging Study, In Healthy VolunteersCompletedNCT00522678Phase 1
• Examine the Effect of Repeat Inhaled Doses of GW870086X on Lung Function in Mild Asthmatic Male SubjectsCompletedNCT00483899Phase 1
• Successful Control and Clinical Effectiveness Of SERETIDE(Salmeterol/Fluticasone Propionate) Study In Asthma.(SUCCESS)CompletedNCT00480649Phase 4
• CONCEPT: A 1-Year Comparison Of A Stable Dose Of SERETIDE® Inhaler With An Adjustable Maintenance Dose Of SYMBICORT® Inhaler. SERETIDE® Inhaler is a Trademark of GSK Group of Companies. SYMBICORT® Inhaler is a Trademark of Astra Zeneca.CompletedNCT00479739Phase 4
• No Resistance After Long Term Treatment SERETIDEWithdrawnNCT00456313Phase 4
• The Safety and Tolerability of GW805858 in Healthy Volunteers and Mild AsthmaticsTerminatedNCT00453791Phase 1
• A Study To Investigate The Effect Of Inhaled Fluticasone Propionate On The Bronchial Responsiveness To Leukotriene D4 In Asthmatics PatientsCompletedNCT00453778Phase 4
• This Study Will Examine the Effects of GSK256066 to Protect Mild Steroid-naive Asthmatics Against an Antigen ChallengeCompletedNCT00445510Phase 2
• Single Dose GW685698X Magnesium Stearate Study In Asthmatic Patients.CompletedNCT00444509Phase 1
• A Long Term Prospective Follow Up Study For The CATO Study (SAS30018/SER9702)CompletedNCT00441675
• Investigating The Pharmacokinetics Of An Inhaled Dose Of A New Corticosteroid In Patients With Impaired Liver FunctionCompletedNCT00419237Phase 1
• A Study Of GSK679586A When Infused Into Healthy And Mild Asthmatic VolunteersCompletedNCT00411814Phase 1
• Evaluation Of Patient Satisfaction Of Metered Dose Inhaler (MDI) With Counter In Asthmatics And Chronic Obstructive Pulmonary Disease Patients (COPD).CompletedNCT00404261Phase 4
• Study on the Effects of an AMP Challenge on Asthmatic Patients Following Treatment With Fluticasone PropionateCompletedNCT00400855Phase 2
• A Study In Pediatric Subjects With Asthma Using ADVAIR HFA, ADVAIR HFA With Spacer, And ADVAIR DISKUSCompletedNCT00400608Phase 4
• A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Persistent Asthma.CompletedNCT00398645Phase 2
• Study To Evaluate GSK256066 In Subjects With Mild Bronchial AsthmaCompletedNCT00380354Phase 2
• Study Of Airway Physiology In Adults. SERETIDE DISKUS® Inhaler and FLIXOTIDE® Inhaler Are Trademarks of GSK Croup of Companies.CompletedNCT00370591Phase 4
• FLOVENT Hydrofluoroalkane (HFA) In 6-12 Month Old SubjectsCompletedNCT00370097Phase 1
• Spacer Comparison In Adult AsthmaticsCompletedNCT00369993Phase 2
• A Study To Determine The Effect Of SB-480848 On AsthmaCompletedNCT00368576Phase 1
• Repeat Dose Study of Fluticasone Propionate/Salmeterol Versus Fluticasone Propionate + Salmeterol In AsthmaticsCompletedNCT00364442Phase 1
• GSK159802 In Healthy Male Subjects And AsthmaticsCompletedNCT00364273Phase 1
• Investigation Of A New Medication (GW642444) In Asthmatic PatientsCompletedNCT00354874Phase 2
• Effects Of Repeat Inhaled Doses Of GW597901X On Patient Safety And Lung Function In Asthmatic SubjectsCompletedNCT00354042Phase 1
• A Comparative Study To Determine If Motivating Asthma Education (Compliance Enhancement) Has An Effect On Asthma ControlCompletedNCT00351143Phase 4
• A Methodology Study To Look At Genes In Lung Cells And Tissue From Asthmatic PatientsTerminatedNCT00331292
• Comparison Of Molecular Targets In Mild To Severe Asthmatics And Healthy SubjectsTerminatedNCT00331058Phase 1
• Pediatric ADVAIR DISKUS Versus Oral Montelukast Chewable TabletsCompletedNCT00328718Phase 3
• Influence Of Different Airflow Resistances On Drug Effect Of 50μg Salmeterol And 6 μg FormoterolCompletedNCT00327353Phase 4
• Assessment Of Disease Pathology And Key Therapeutic Targets In Severe AsthmaTerminatedNCT00327197Phase 1
• The Effect Of AVANDIA On The Late Asthmatic ResponseCompletedNCT00318630Phase 1
• Viapaed Study In Children And Adolescents With AsthmaCompletedNCT00315744Phase 4
• Study Of Patients With Allergic Rhinitis And AsthmaCompletedNCT00296530Phase 4
• Airway Hyper-responsiveness Study In Asthma Using Salmeterol/Fluticasone Propionate Combination ProductCompletedNCT00291382Phase 4
• Study In Asthma ControlTerminatedNCT00273026Phase 4
• Study With GW274150 In Patients With Mild AsthmaCompletedNCT00273013Phase 1
• Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.CompletedNCT00169546Phase 4
• Pediatric Asthma Study Using Stepwise Treatment With Two Food And Drug Administration Approved Asthma MedicationsCompletedNCT00158834Phase 3
• Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In ChildrenCompletedNCT00144846Phase 3
• A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or ExerciseCompletedNCT00118690Phase 4
• Study Of Asthma And Genetics In Patients To Be Treated With Fluticasone Propionate/Salmeterol Or Salmeterol XinafoateCompletedNCT00102882Phase 4
• Study Of Asthma In Patients Of African DescentCompletedNCT00102765Phase 4