CSL Limited: Renal Insufficiency, Chronic trials

The registry lists 15 Renal Insufficiency, Chronic studies with CSL Limited as lead sponsor. 1 are open to participants now and 8 have results posted.

Phase 2 6Phase 3 5No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe PruritusRecruitingNCT06593392Phase 2
• Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and HyperkalemiaTerminatedNCT03087058Phase 2Results posted
• Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney DiseaseCompletedNCT03071263Phase 2Results posted
• A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)CompletedNCT01810939Phase 3Results posted
• A Phase 3 Extension Study to Investigate the Long-term Safety, Tolerability and Efficacy of PA21, a Phosphate Binder in Dialysis PatientsCompletedNCT01464190Phase 3Results posted
• Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)CompletedNCT01371747Phase 2Results posted
• Evaluation of Patiromer Titration in Heart Failure Patients With Chronic Kidney DiseaseCompletedNCT01130597Phase 2Results posted
• Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)CompletedNCT00994318Phase 3Results posted
• Study of Phosphate Levels in Patients With Chronic Kidney DiseaseCompletedNCT00824460Phase 2Results posted
• Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Hemodialysis PatientsWithdrawnNCT05625542
• Cross-sectional Study to Assess Prevalence and Burden of CKD-associated Pruritus in Haemodialysis PatientsCompletedNCT05524467
• RAYALDEE Non Interventional Study (NIS) on Effectiveness in ND-CKD SHPT PatientsCompletedNCT05460234
• Trial Evaluating the Efficacy and Safety of Patiromer in Chinese SubjectsCompletedNCT05136664Phase 3
• Study of the Prevalence of Iron Deficiency in Patients With Chronic Renal Failure But Non-Dialysis (CARENFER IRC-ND)Status unknownNCT04123145Not applicable
• PA21 Safety and Efficacy in Adult Chinese SubjectsCompletedNCT03644264Phase 3