Centre for Addiction and Mental Health: Tobacco Use Disorder trials

The registry lists 29 Tobacco Use Disorder studies with Centre for Addiction and Mental Health as lead sponsor. 4 are open to participants now and 5 have results posted.

Phase 1 1Phase 2 7Phase 3 1Phase 4 9No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• tDCS Plus Varenicline for Smoking CessationRecruitingNCT06798324Phase 4
• Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation TrialRecruitingNCT06534047Phase 4
• Implementation of Transcranial Magnetic Stimulation for Smoking CessationRecruitingNCT06346028Phase 4
• Smoking Cessation and Menstrual Cycle PhaseRecruitingNCT05515354Phase 4
• Deep rTMS and Varenicline for Smoking CessationCompletedNCT04083144Not applicableResults posted
• Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco AddictionCompletedNCT01876810Phase 2Results posted
• Distribution of Bupropion and Varenicline to Increase Smoking Cessation AttemptsCompletedNCT01023659Phase 4Results posted
• STOP Study: Effectiveness of Zyban in a Clinical PopulationCompletedNCT01015170Phase 4Results posted
• Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and CessationCompletedNCT00289653Not applicableResults posted
• Cytisine for Smoking CessationCompletedNCT05729243Phase 4
• Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco DependenceCompletedNCT03841292Not applicable
• Combining rTMS With Varenicline to Prevent Smoking Lapse in SchizophreniaWithdrawnNCT03497299Phase 2
• Personalized Dosing of Nicotine Replacement (NRT to Effect)CompletedNCT03000387Phase 4
• Nicotine Metabolizers and [11C]-(+)-PHNOCompletedNCT02514720Not applicable
• Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine ReplacementTerminatedNCT02439944Phase 2/3
• The MATCH (Medication Aids for Tobacco Cessation and Health) StudyCompletedNCT02146911Not applicable
• Electronic Cigarettes in Daily Dependent SmokersCompletedNCT02108626Phase 4
• A Dietary Supplement for Early Cigarette WithdrawalCompletedNCT02042521Phase 2
• Transcranial Direct Current Stimulation in a Smoking Cessation TrialWithdrawnNCT01710410Phase 2
• Prazosin for Smoking CessationTerminatedNCT01642433Phase 2
• The Effect of Varenicline on D2/D3 Receptor Binding in SmokersCompletedNCT01632189Not applicable
• Effects of rTMS on Cigarette Smoking and Cognition in SchizophreniaCompletedNCT01523730Not applicable
• Smoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in HumansCompletedNCT01302262
• Baclofen for Smoking Cessation in a Non-Psychiatric PopulationTerminatedNCT01228994Phase 2
• Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar DisorderCompletedNCT01093937Not applicable
• Effect of Varenicline on Reactivity to Smoking and Drinking CuesCompletedNCT00873535Not applicable
• Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With SchizophreniaCompletedNCT00407277Not applicable
• Testing a Full Substitution Therapy Approach As Treatment of Tobacco DependenceTerminatedNCT00390923Not applicable
• Use of Pharmacotherapy to Reduce Cue-responsiveness in SmokersCompletedNCT00133757Phase 1