Centers for Disease Control and Prevention: Malaria trials

The registry lists 36 Malaria studies with Centers for Disease Control and Prevention as lead sponsor. 0 are open to participants now and 4 have results posted.

Phase 1 1Phase 2 2Phase 3 4Phase 4 13No phase 18(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, BrazilCompletedNCT03610399Not applicableResults posted
• Artemether-lumefantrine for Treatment of P. Falciparum Malaria in BrazilCompletedNCT02600767Not applicableResults posted
• Validation of RealAmp Method for the Diagnosis of Malaria in Endemic Areas of BrazilCompletedNCT02371395Results posted
• Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, BrazilCompletedNCT02043652Not applicableResults posted
• Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in LiberiaCompletedNCT06300970Phase 4
• Assessing the Impact of Group Antenatal Care on IPTp Uptake in TanzaniaTerminatedNCT04148690Not applicable
• Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in MalawiCompletedNCT02645513Not applicable
• In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum MalariaCompletedNCT02637128Phase 4
• Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western KenyaWithdrawnNCT01810731Phase 2/3
• Ethiopia Antimalarial in Vivo Efficacy Study 2012CompletedNCT01680406Phase 4
• Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in MalawiCompletedNCT01326754Not applicable
• Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in MalawiCompletedNCT01120145
• Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV)TerminatedNCT01107145Phase 4
• Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in BrazilTerminatedNCT01082731Phase 4
• Pharmacokinetics of Mefloquine-Artesunate in Pregnant Women With Uncomplicated Plasmodium Falciparum InfectionWithdrawnNCT01082718Phase 2/3
• Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in ChildrenCompletedNCT01082705Phase 3
• Ethiopia Malaria Therapeutic Efficacy StudyCompletedNCT01052584Not applicable
• Evaluation of Insecticide Treated Nets and Wall Liners for the Prevention of MalariaCompletedNCT01043796Phase 3
• Non-malarial Febrile Illness in Children in Areas of Perennial Malaria TransmissionCompletedNCT01043744Not applicable
• Mefloquine Bioequivalence Among 3 Commercially Available Tablets.CompletedNCT00544024
• Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum MalariaCompletedNCT00425763Phase 4
• Use of Rapid Diagnostic Tests for Malaria Case Management in KenyaCompletedNCT00336388Not applicable
• Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the PhilippinesCompletedNCT00229775Not applicable
• Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in MalawiCompletedNCT00164710Phase 4
• Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in MalawiCompletedNCT00164359Phase 4
• Efficacy of Combination Therapy for Prevention of Effects of Malaria During PregnancyCompletedNCT00164255Phase 4
• Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in PeruCompletedNCT00164216
• Adherence to Lumefantrine-ArtemetherCompletedNCT00153491
• In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected AdultsCompletedNCT00144352Phase 4
• Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for MalariaCompletedNCT00140361Phase 4
• Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate ResistanceCompletedNCT00137657Phase 4
• The Effect of Folic Acid on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western KenyaCompletedNCT00130065Phase 4
• Antimalarial Drug Resistance in MaliCompletedNCT00127998Not applicable
• Chlorproguanil-Dapsone in Pregnant WomenTerminatedNCT00126971Phase 1
• Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: MalawiCompletedNCT00126906Not applicable
• Intermittent Preventive Treatment With Antimalarials in Kenyan InfantsCompletedNCT00111163Not applicable