Cancer Institute and Hospital, Chinese Academy of Medical Sciences: all 387 studies

Page 1 of 4. Open to participants first (275), then studies with results posted, then the rest; newest registration first within each.

• Clinical Study of Three-dimensional Lattice Radiotherapy Combined With PD-1/PD-L1 Inhibitors in the Treatment of Advanced Solid TumorsRecruitingNCT07865793Phase 2
• The QL1706 Combined With Chemotherapy and Either Cetuximab or Bevacizumab in Potentially Resectable Colorectal Cancer Patients With Liver MetastasesNot yet recruitingNCT07863869Phase 1/2
• Phase I Study of In Vivo CAR-Tumor Technology for the Treatment of Advanced Malignant TumorsNot yet recruitingNCT07859462Phase 1
• Radiotherapy Target Volume Delineation in Locally Advanced Esophageal Cancer in the Immunotherapy EraRecruitingNCT07858630
• Phase 1 Study of ATRA Plus a PD-1 Inhibitor in EGFR-Mutant NSCLC After Third-Generation EGFR-TKI ResistanceNot yet recruitingNCT07842887Phase 1
• Rimegepant Plus Toripalimab in Advanced Urothelial Carcinoma After Failure of Standard TherapyRecruitingNCT07835035Phase 1
• Video-Assisted Thoracoscopic Surgery Combined With Radiofrequency Ablation Versus VATS Alone for Multiple Primary Lung CancerNot yet recruitingNCT07819669Not applicable
• YSCH-01 Via Nebulization in Pulmonary Metastasis of Advanced Solid Tumors and Non-small Cell Lung Cancer (NSCLC)RecruitingNCT07793500Early Phase 1
• A Phase II Study of Stapokibart Combined With Immune Checkpoint Inhibitors in Relapsed/Refractory LymphomaNot yet recruitingNCT07791615Phase 2
• Establishment of a Multi-omics Prediction Model for Early Triple-negative Breast Cancer Based on UPGRADE-TNBC StudyRecruitingNCT07773818
• COLORS-Validate Study of Decision-Support Software for Surgical Sequencing in Colorectal Liver MetastasesNot yet recruitingNCT07760558
• SHR-1701 Plus Apatinib for Second-Line Treatment in Targeted-Immune Pretreated Advanced Hepatocellular CarcinomaNot yet recruitingNCT07749859Phase 2
• An MRI-Based Study of Intelligent Pathological Subtyping and Grading of Renal TumorsRecruitingNCT07743749
• Multimodal Ablation Combined With Perioperative Tislelizumab and Chemotherapy for Resectable II-IIIB NSCLCNot yet recruitingNCT07729670Phase 2
• Fruquintinib Plus Anti-EGFR Antibody for Third-Line Treatment of RAS Wild-Type mCRCRecruitingNCT07724223Phase 2
• Sintilimab Versus Mitomycin in Combination With Capecitabine and IMRT for Limited-stage Anal Squamous Cell CarcinomaRecruitingNCT07692152Phase 3
• Chemoradiotherapy and SHR-1701 in Patients With Unresectable Gastric CancerRecruitingNCT07689851Phase 2
• A Phase II Study of Radiation Therapy to Treat Refractory Breast CancerNot yet recruitingNCT07672743Not applicable
• Characterization of Multi-Omics Landscapes and AI Pathological Prediction Model for Long-Term Survival in NSCLC ImmunotherapyRecruitingNCT07668037
• Inhaled mRNA Immunotherapy for Patients With Advanced Lung Cancer or Pulmonary Metastatic Solid TumorsNot yet recruitingNCT07657611Early Phase 1
• CIB In Vivo CAR-T Lentiviral Injection in Patients With Advanced Malignant TumorsNot yet recruitingNCT07657585Phase 1
• Predictive Value of Tumor Microenvironment PET/CT for Response and Prognosis in Aggressive LymphomaRecruitingNCT07657494Not applicable
• Risk-Stratified Hypofractionated Radiotherapy After Breast-Conserving Surgery for Early Breast CancerNot yet recruitingNCT07657442Not applicable
• CONNEctome-guided Navigation for Eloquent-area Tumor Surgery TrialRecruitingNCT07657403Not applicable
• Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer PainRecruitingNCT07657390Phase 1/2
• Platform Study of VSV-Based Recombinant Oncolytic Viruses for the Treatment of Advanced Malignant TumorsRecruitingNCT07656116Phase 1
• QH101 Cell Injection in Patients With Brain, Brain (Spinal) Meninges, and Spinal Cord Metastatic Malignant Solid TumorsNot yet recruitingNCT07656103Early Phase 1
• Safety and Efficacy of Intravenous IDOV-Immune in Patients With Advanced Solid TumorsEnrolling by invitationNCT07656090Early Phase 1
• OVV-01 Injection Combined With AK112 Injection for the Treatment of Patients With Advanced Soft Tissue Sarcoma (STS)Not yet recruitingNCT07650838Phase 2
• OVV-01 Intravenous and Intratumoral Injection Combined With AK112 for the Treatment of Advanced Solid TumorsNot yet recruitingNCT07650825Phase 1
• Efficacy and Safety of Postoperative Concurrent Chemoradiotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma: A Multicenter Prospective Phase II StudyRecruitingNCT07636824Phase 2
• PTC-Guided Atorvastatin Plus Axitinib and Toripalimab in Advanced RCCNot yet recruitingNCT07630363Phase 1/2
• Study of Wenyang Tongbi Formula in the Treatment of Chemotherapy-Induced PolyneuropathyNot yet recruitingNCT07626528Early Phase 1
• Real-World RAIRI-Guided Risk Stratification for Adjuvant Therapy Benefit After Chemoradiotherapy in NPCRecruitingNCT07618078
• Preoperative Radiotherapy and Anlotinib With or Without Penpulimab for Soft Tissue SarcomaNot yet recruitingNCT07612098Phase 2
• Analysis of Different Second Line Treatment in Advanced NSCLC Patients Progressing After 1st Line Immune Checkpoint Inhibitor TherapyNot yet recruitingNCT07596524
• RAIRI Model-Guided Adjuvant Therapy in Nasopharyngeal CarcinomaRecruitingNCT07590024Phase 3
• Precision Radiotherapy for Refractory Brain Metastases: A Multicenter StudyNot yet recruitingNCT07586657Phase 3
• Sacituzumab Tirumotecan for Pancreatic CancerNot yet recruitingNCT07561463Phase 2
• Adebrelimab Combined With Chemoradiotherapy in Patients With Large Bulky Stage III Unresectable Non-Small Cell Lung CancerNot yet recruitingNCT07560358Phase 3
• A Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of BRII-5395 in Combination With Sintilimab and Bevacizumab in Advanced Hepatitis B Virus Related Hepatocellular CarcinomaRecruitingNCT07557251Phase 1
• Zorifertinib Plus Intra-Ommaya CSF Chemotherapy for Leptomeningeal Progression in NSCLC After Third-Generation EGFR-TKINot yet recruitingNCT07551414Phase 2
• BR101 in Patients With Relapsed/Refractory Multiple MyelomaNot yet recruitingNCT07537049Phase 1
• Protein Supplementation for Radiation- Induced Oral Mucositis in Head and Neck Cancer Patients Receiving RadiotherapyNot yet recruitingNCT07531563Not applicable
• A Phase II Single-arm Clinical Study in the Treatment of Locally Advanced Esophageal Cancer After Failed Neoadjuvant ChemoimmunotherapyNot yet recruitingNCT07530549Phase 2
• Detecting CREPT in Urine for Bladder Cancer Diagnosis and MonitoringRecruitingNCT07514897
• Hypofractionated Radiotherapy for Postoperative Intermediate-Risk Head and Neck Squamous Cell CarcinomaNot yet recruitingNCT07507058Not applicable
• A Retrospective Real-World Study Based on RATIONALE-307RecruitingNCT07478809
• Darolutamide ± ADT as Neoadjuvant Therapy in High-Risk/Very High-Risk Localized Prostate CancerNot yet recruitingNCT07476677Phase 2
• A Study to Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell MalignanciesNot yet recruitingNCT07476378Not applicable
• An Open-Label, Single-Arm, Dose-Escalation Phase I Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of EDB-102 in Patients With EGFR L858R-Mutant, Third-Generation TKI-Resistant Advanced Non-Small Cell Lung Cancer With Liver MetastasesNot yet recruitingNCT07461727Phase 1
• Artificial Intelligence-assisted HER2 Expression Assessment in Urothelial Carcinoma Based on Imaging-pathology OmicsEnrolling by invitationNCT07454941
• Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients.RecruitingNCT07443397Phase 3
• Remodeling of MHC-related Immune Microenvironment in MIBC After Neoadjuvant TherapyNot yet recruitingNCT07440901
• Intraperitoneal SK-NK Cell Injection for Advanced Ovarian Cancer With Massive AscitesRecruitingNCT07435701Phase 1/2
• Neoadjuvant Aitua (PD-1/CTLA-4 Bispecific) Plus Nab-Paclitaxel and Carboplatin for Advanced High-Grade Serous Ovarian CancerNot yet recruitingNCT07432594Phase 2
• Phase 2 Clinical Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Platinum Chemotherapy Versus Platinum Chemotherapy in the Treatment of Second-/Third-line Triple Negative Breast Cancer (TNBC)Not yet recruitingNCT07413601Phase 2
• A Phase I Platform Study of Target-Based Screened CAR-Macrophages for the Treatment of Advanced Malignant TumorsNot yet recruitingNCT07409766Early Phase 1
• BaiXiaoAi AI Companion for Cancer Patient Follow-upNot yet recruitingNCT07396142
• Preoperative Hypofractionated RT + Immunotherapy & Surgery for Retroperitoneal Sarcoma (FUSION-02)Not yet recruitingNCT07396116Not applicable
• Study of KRAS-Specific Vaccine in Patients With KRAS-Mutated Solid TumorsNot yet recruitingNCT07396090Not applicable
• A Platform Study of In Vivo CAR-T for Treating Advanced Malignant Tumors Based on Target ScreeningRecruitingNCT07395479Early Phase 1
• A Study of Postoperative Regional Nodal Radiotherapy in Intermediate-risk Breast CancerNot yet recruitingNCT07385365Phase 3
• CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTCRecruitingNCT07383246Phase 3
• Response-Based Local Therapy for Regionally Advanced Breast CancerRecruitingNCT07376538Phase 2
• Comparison of the Effect of Surgical Resection Based on Lesion Extent Before and After Neoadjuvant Therapy in Patients With Stage II-IIIB Non-Small Cell Lung Cancer: A Single-Center, Real-World, Open-Label StudyEnrolling by invitationNCT07373899
• Omitting Nasogastric Tube Decompression in Minimally Invasive PancreaticoduodenectomyNot yet recruitingNCT07370116Phase 2
• Safety, Tolerability and Preliminary Efficacy of NEUK203-13 in Refractory Neuroendocrine Tumor PatientsRecruitingNCT07366658Phase 1
• A Phase I Study of CREPT-618 in Locally Advanced HCCRecruitingNCT07364357Phase 1
• Neoadjuvant Therapy With Tislelizumab for dMMR/MSI-H Stage II-III Colorectal CancerRecruitingNCT07352280
• Multi-omics Analysis of Renal Cell Carcinoma Mechanisms; Drug Sensitivity Testing in Patient-Derived Cell-based MicrotumorsNot yet recruitingNCT07351266
• Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid TumorsRecruitingNCT07349160Early Phase 1
• Glecirasib Combined With Ivonescimab for First-line Treatment of KRAS G12C-mutated NSCLCNot yet recruitingNCT07339839Phase 1/2
• Adaptive Radiotherapy for Genitourinary CancersRecruitingNCT07324798Not applicable
• Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast CancerNot yet recruitingNCT07317778Phase 2
• Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2)Not yet recruitingNCT07307053Phase 1/2
• Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)Not yet recruitingNCT07306390
• An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC)RecruitingNCT07298239Early Phase 1
• Fruquintinib Combined With Trifluridine/Tipiracil Versus Bevacizumab Combined With Trifluridine/Tipiracil for Advanced Metastatic Colorectal CancerNot yet recruitingNCT07286695Phase 2
• This Study is an Open-lable, Early Study to Evaluate the Safety, Feasibility, Cytokinetics, and Preliminary Efficacy of GC511B in DLL3+ Relapsed/Refractory Small Cell Lung Cancer.RecruitingNCT07249879Phase 1
• A Multicenter Phase III Clinical Study and Translational Research on Adaptive Neoadjuvant Therapy of De-escalation and Escalation for HER2-Positive Breast Cancer Based on Multi-Omics Response Evaluation ModelNot yet recruitingNCT07239271Phase 3
• Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellular CarcinamoRecruitingNCT07239245Phase 2
• Iparomlimab/Tuvonralimab Injection Plus CCRT in LACCRecruitingNCT07232654Phase 2
• The Efficacy and Safety of Trastuzumab Rezetecan (SHR-A1811) in HER2-Low Unresectable/Metastatic Breast Cancer Patients With Visceral CrisisRecruitingNCT07203729Phase 2
• Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCHRecruitingNCT07187193Phase 2
• Efficacy and Safety of the RD Regimen(Lenalidomide, Dexamethasone) for Rosai-Dorfman DiseaseRecruitingNCT07187167Phase 2
• The Application of Symptoms Management Program Based on the Patient Reported Outcome After EsophagectomyRecruitingNCT07187154Not applicable
• QL706 + Chemo ± Bevacizumab in Anti-PD-(L)1-Resistant R/M Cervical CancerNot yet recruitingNCT07186868
• Adjuvant Radiotherapy of Sintilimab Versus TACE for HCCRecruitingNCT07186621Phase 3
• Efficacy of Neoadjuvant Immunotherapy in Patients With Lung CancerRecruitingNCT07166003
• Neoadjuvant Chemotherapy Combined With Preoperative Radiotherapy for Locally Advanced Breast CancerNot yet recruitingNCT07164872Not applicable
• MiniPDX-based Postoperative Adjuvant Therapy for Biliary Tract CancerRecruitingNCT07156058Not applicable
• Study of Allogeneic Anti-PSMA CAR-NK Cell for Metastatic Castration-Resistant Prostate CancerRecruitingNCT07156045Early Phase 1
• Sintilimab in Combination With Surufatinib and Temozolomide in the Advanced Neuroendocrine CarcinomaNot yet recruitingNCT07156019Phase 2
• An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular TypingNot yet recruitingNCT07141771Phase 1/2
• Treatment Intermittent Periods Based on ctDNA-MRD（Circulating Tumor DNA-minimal Residual Disease） Status in Advanced HER2-Positive Breast CancerNot yet recruitingNCT07132502
• SHR-A1811 Combine With Pyrotinib for Locally Advanced/Metastatic HER2 Positive Breast CancerNot yet recruitingNCT07132242Phase 2
• Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLCRecruitingNCT07120282Phase 2
• Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLCRecruitingNCT07110103Phase 2
• Umbilical Cord Blood Megakaryocyte Injection (XJ-MK-002) for Cancer Therapy-Induced Thrombocytopenia (CTIT)RecruitingNCT07110090Phase 1

← Cancer Institute and Hospital, Chinese Academy of Medical Sciences overview and focus areas