Cancer Institute and Hospital, Chinese Academy of Medical Sciences: Breast Neoplasms trials

The registry lists 49 Breast Neoplasms studies with Cancer Institute and Hospital, Chinese Academy of Medical Sciences as lead sponsor. 30 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 20Phase 3 6Phase 4 1No phase 22(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase II Study of Radiation Therapy to Treat Refractory Breast CancerNot yet recruitingNCT07672743Not applicable
• Risk-Stratified Hypofractionated Radiotherapy After Breast-Conserving Surgery for Early Breast CancerNot yet recruitingNCT07657442Not applicable
• A Study of Postoperative Regional Nodal Radiotherapy in Intermediate-risk Breast CancerNot yet recruitingNCT07385365Phase 3
• Response-Based Local Therapy for Regionally Advanced Breast CancerRecruitingNCT07376538Phase 2
• The Efficacy and Safety of Trastuzumab Rezetecan (SHR-A1811) in HER2-Low Unresectable/Metastatic Breast Cancer Patients With Visceral CrisisRecruitingNCT07203729Phase 2
• Neoadjuvant Chemotherapy Combined With Preoperative Radiotherapy for Locally Advanced Breast CancerNot yet recruitingNCT07164872Not applicable
• Treatment Intermittent Periods Based on ctDNA-MRD（Circulating Tumor DNA-minimal Residual Disease） Status in Advanced HER2-Positive Breast CancerNot yet recruitingNCT07132502
• SHR-A1811 Combine With Pyrotinib for Locally Advanced/Metastatic HER2 Positive Breast CancerNot yet recruitingNCT07132242Phase 2
• Hypofractionated vs Conventional RT After Prosthetic Breast ReconstructionRecruitingNCT07084519Phase 3
• Oral Metronomic Capecitabine Combined With Pyrotinib in ADC-treated HER2-positive Metastatic Breast CancerNot yet recruitingNCT07019337Phase 2
• PD-L1 Inhibitor + RT ± Ursodeoxycholic Acid in Recurrent/Metastatic HER2-Neg Breast CancerNot yet recruitingNCT06842472Phase 2
• Familial Breast Cancer in ChinaNot yet recruitingNCT06833216
• A Study Comparing the Differences Between Young and Non-young Breast CancerEnrolling by invitationNCT06793306
• Hypofractionated Postoperative Regional Nodal Irradiation for Patients With Intermediate-risk Breast CancerRecruitingNCT06757621Phase 3
• Neoadjuvant Treatment of Triple-Negative Breast Cancer with Stereotactic Radiotherapy, PD-1 Monoclonal Antibody, and ChemotherapyNot yet recruitingNCT06691594Phase 2
• Prospective Validation and Application of an Artificial Intelligence-based Model for Evaluating the Efficacy of Breast Cancer Patients After Neoadjuvant TherapyRecruitingNCT06649565
• Super-Hypofractionated Partial Breast IrradiationRecruitingNCT06615466Not applicable
• A Study for Dynamic Prediction Model of Breast Cancer Bone MetastasesNot yet recruitingNCT06544668
• SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast CancerRecruitingNCT06411457Phase 2
• Intensive Adjuvant Therapy for TNBC with BRCA Gene MutationEnrolling by invitationNCT06405295
• Effect of (neo)Adjuvant Therapy on Lipids in Young Breast Cancer PatientsEnrolling by invitationNCT06405269
• Trastuzumab Deruxtecan (T-DXd) With Pyrotinib in First-line HER2-positive Unresectable or Metastatic Breast Cancer TrialNot yet recruitingNCT06245824Phase 4
• Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast CancerNot yet recruitingNCT06229067Phase 2
• Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast CancerRecruitingNCT06197581Not applicable
• Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast CancerRecruitingNCT05983107Phase 2
• Study of Utidelone Based Neoadjuvant Treatment on Early High-risk or Locally Advanced Breast CancerNot yet recruitingNCT05983094Phase 2
• Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer PatientsRecruitingNCT05762900Phase 2
• A Prospective Study of Preoperative Tumor-bed Boost Followed by Oncoplastic Surgery and Adjuvant Whole Breast Radiotherapy for Early Stage Breast Cancer (BIRKIN)RecruitingNCT05603078Not applicable
• The Efficacy and Safety of Dalpiciclib Plus Endocrine Therapy in HR-positive / HER2-negative Advanced Breast Cancer Patients With Visceral CrisisNot yet recruitingNCT05431504Phase 2
• Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast CancerRecruitingNCT05345860Not applicable
• RWS of Paclitaxel Liposome Combined With Anti-HER-2 Monoclonal AntibodyActive, not recruitingNCT06481553
• Mitoxantrone Hydrochloride Liposome Combined With Capecitabine in Patients With HER-2 Negative Advanced Breast CancerStatus unknownNCT06156761Not applicable
• Neoadjuvant Inetetamab Combined With Pertuzumab and Paclitaxel/Carboplatin for Breast CancerStatus unknownNCT05749016Phase 2
• Oral Vinorelbine and Capecitabine in Advanced HER2-negative Breast CancerStatus unknownNCT05747326Phase 2
• Chidamide in Combination With Vincristine Metronomic Chemotherapy for Advanced Triple-negative Breast CancerStatus unknownNCT05747313Phase 1/2
• A Phase II Study Evaluating the Efficacy and Safety of Pembrolizumab in Combination With Chemotherapy as Neoadjuvant Therapy for Triple-negative Breast CancerStatus unknownNCT05681728Phase 2
• The Influence of Treatment Position (Prone vs. Supine) on Whole Breast TargetStatus unknownNCT05609058Not applicable
• Multi-center Study of Deep Learning AI in Breast MassStatus unknownNCT05443672
• A Study of RC48-ADC for the Treatment of HER2-expression Metastatic Breast Cancer With Abnormal Activation of PAM PathwayStatus unknownNCT05331326Phase 2
• A Prospective Study of Hypothyroidism After Radiotherapy for Breast CancerCompletedNCT04528225
• Study of Tislelizumab Plus Chemotherapy vs Chemotherapy as Perioperative Treatment in Participants With HER2 Negative Breast CancerStatus unknownNCT04498793Phase 2
• Safety and Efficacy of Toripalimab in HER2- Metastatic Breast Cancer Patients Treated With Metronomic VinorelbineStatus unknownNCT04389073Phase 2
• Postmastecomy Internal Mammary Nodal Irradiation for High-risk Breast Cancer PatientsActive, not recruitingNCT04320979Phase 3
• Taxane Induced Peripheral Neuropathy in Chinese Patients With Breast CancerStatus unknownNCT04068090
• Compare Apatinib Plus Capecitabine Versus Capecitabine in Maintenance Therapy for Patients With Advanced Triple-negative Breast CancerStatus unknownNCT03775928Phase 2
• Randomized Trial of Accelerated Partial Breast IrradiationCompletedNCT03583619Not applicable
• Accelerated Partial Breast Irradiation With IMRT in Early Breast CancerActive, not recruitingNCT03583580Not applicable
• A Study to Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal Breast Cancer Patients With CYP2D6*10 Mutations （STEP）Status unknownNCT03137368Phase 3
• Randomized Study of Hypofractionated and Conventional Fractionation Radiotherapy After Breast Conservative SurgeryCompletedNCT01413269Phase 3