Brigham and Women's Hospital: Amyloidosis trials

The registry lists 10 Amyloidosis studies with Brigham and Women's Hospital as lead sponsor. 3 are open to participants now and 2 have results posted.

Phase 1 1Phase 2 4Phase 3 2Phase 4 1No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• [64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid CardiomyopathyRecruitingNCT07560306Phase 3
• Exercise Training in Transthyretin Cardiac AmyloidosisRecruitingNCT05797857Not applicable
• Molecular Imaging of Primary Amyloid CardiomyopathyRecruitingNCT02641145Not applicable
• Doxycycline and TUDCA in Patients With Transthyretin Amyloid CardiomyopathyCompletedNCT01855360Phase 1/2Results posted
• Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission TomographyCompletedNCT01683825Phase 4Results posted
• Molecular Imaging of Myocardial Fibrosis in Cardiac AmyloidosisActive, not recruitingNCT05619302Phase 3
• ION-682884 in Patients With TTR Amyloid CardiomyopathyWithdrawnNCT04843020Phase 2
• 24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy PatientsTerminatedNCT03702829Phase 2
• Risk Evaluation and Education for Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging (REVEAL-SCAN)CompletedNCT02959489Not applicable
• The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the HeartWithdrawnNCT02627820Phase 2