Boehringer Ingelheim: Hepatic Insufficiency trials

The registry lists 13 Hepatic Insufficiency studies with Boehringer Ingelheim as lead sponsor. 0 are open to participants now and 4 have results posted.

Phase 1 12Phase 4 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver ProblemsCompletedNCT05731895Phase 1Results posted
• A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver ProblemsCompletedNCT05661344Phase 1Results posted
• Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy VolunteersCompletedNCT02191865Phase 1Results posted
• Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver FunctionCompletedNCT01111318Phase 1Results posted
• A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver ProblemsCompletedNCT06957756Phase 1
• A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver ProblemsCompletedNCT03842761Phase 1
• Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy VolunteersCompletedNCT02265627Phase 1
• Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic ImpairmentCompletedNCT02259855Phase 1
• Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic InsufficiencyCompletedNCT02249442Phase 1
• Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of NevirapineCompletedNCT02184091Phase 1
• Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy SubjectsCompletedNCT02183376Phase 1
• Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionCompletedNCT02170571Phase 1
• A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic FunctionsCompletedNCT00144248Phase 4