Assembly Biosciences: Hepatitis B, Chronic trials

The registry lists 17 Hepatitis B, Chronic studies with Assembly Biosciences as lead sponsor. 0 are open to participants now and 7 have results posted.

Phase 1 10Phase 2 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B InfectionTerminatedNCT04820686Phase 2Results posted
• A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT04781647Phase 2Results posted
• A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase InhibitorsTerminatedNCT04454567Phase 2Results posted
• A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus InfectionTerminatedNCT04398134Phase 2Results posted
• A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B PatientsTerminatedNCT03780543Phase 2Results posted
• A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)CompletedNCT03577171Phase 2Results posted
• A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B InfectionCompletedNCT03576066Phase 2Results posted
• A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT06384131Phase 1
• A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy SubjectsCompletedNCT05569941Phase 1
• A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus InfectionCompletedNCT05414981Phase 1
• A Study to Evaluate the Mass Balance Absorption and AME of VBRCompletedNCT04637139Phase 1
• A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy AdultsCompletedNCT04271592Phase 1
• A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy AdultsCompletedNCT04142762Phase 1
• A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy AdultsCompletedNCT04083716Phase 1
• A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis BCompletedNCT03714152Phase 1
• Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis BCompletedNCT03109730Phase 1/2
• A Study in Healthy Volunteers and Patients With Chronic Hepatitis BCompletedNCT02908191Phase 1