Arrowhead Pharmaceuticals: all 51 studies

Page 1 of 1. Open to participants first (10), then studies with results posted, then the rest; newest registration first within each.

• A Trial to Evaluate the Efficacy and Safety of ARO-INHBE in Adults With Metabolic Dysfunction-Associated SteatohepatitisNot yet recruitingNCT07859813Phase 2
• A First-In-Human Study of ARO-033 in Adult ParticipantsRecruitingNCT07662096Phase 1
• Study of Zodasiran in Adolescent Participants With Homozygous Familial HypercholesterolemiaRecruitingNCT07473843Phase 3
• Study of Inhaled ARO-RAGE in Allergen-induced Mild AsthmaRecruitingNCT07241546Phase 2
• Study of ARO-DIMERPA in Adult Participants With Mixed HyperlipidemiaRecruitingNCT07223658Phase 1/2
• Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's DiseaseRecruitingNCT07221344Phase 1/2
• A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes MellitusRecruitingNCT06937203Phase 1/2
• Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute PancreatitisRecruitingNCT06880770Phase 3
• Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCSAvailableNCT06796426
• A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusRecruitingNCT06700538Phase 1/2
• Study of ARO-MMP7 Inhalation Solution in Healthy Participants and Participants With Idiopathic Pulmonary FibrosisCompletedNCT05537025Phase 1/2Results posted
• Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung DiseaseTerminatedNCT05292950Phase 1/2Results posted
• Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)TerminatedNCT05217667Phase 2Results posted
• Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)CompletedNCT05089084Phase 3Results posted
• Study of Plozasiran (ARO-APOC3) in Adults With Mixed DyslipidemiaCompletedNCT04998201Phase 2Results posted
• Study of ARO-ANG3 in Adults With Mixed DyslipidemiaCompletedNCT04832971Phase 2Results posted
• Study to Evaluate ARO-APOC3 in Adults With Severe HypertriglyceridemiaCompletedNCT04720534Phase 2Results posted
• Study of ARO-ENaC in Healthy Volunteers and in Patients With Cystic FibrosisTerminatedNCT04375514Phase 1/2Results posted
• Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASHCompletedNCT04202354Phase 1/2Results posted
• Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)CompletedNCT03946449Phase 2Results posted
• Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)CompletedNCT03945292Phase 2Results posted
• Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)CompletedNCT03365947Phase 1/2Results posted
• A Study of ARC-521 Injection in Normal Adult Volunteers and Patients With Chronic Hepatitis B (CHB)TerminatedNCT02797522Phase 1Results posted
• Extension Study of the Safety and Efficacy of Multi-dose Intravenous ARC-520 in Patients With Chronic Hepatitis B (HBV) InfectionTerminatedNCT02738008Phase 2Results posted
• A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Positive, Chronic Hepatitis B Virus InfectionTerminatedNCT02604212Phase 2Results posted
• A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Negative, Chronic Hepatitis B Virus (HBV) InfectionTerminatedNCT02604199Phase 2Results posted
• Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV)TerminatedNCT02577029Phase 2Results posted
• A Study of ARC-520 at Varying Infusion Rates in Healthy Adult VolunteersCompletedNCT02535416Phase 1Results posted
• Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B VirusTerminatedNCT02452528Phase 2Results posted
• A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)TerminatedNCT02363946Phase 1Results posted
• A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) InfectionTerminatedNCT02065336Phase 2Results posted
• A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)Active, not recruitingNCT07037771Phase 3
• Long-Term Safety and Efficacy of Plozasiran in Adults With HypertriglyceridemiaActive, not recruitingNCT06822790Phase 3
• Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2Active, not recruitingNCT06672445Phase 1
• Phase 3 Study of Plozasiran in Adults With HypertriglyceridemiaCompletedNCT06347133Phase 3
• Study of Plozasiran in Adults With Severe HypertriglyceridemiaCompletedNCT06347016Phase 3
• Study of Plozasiran (ARO-APOC3) in Adults With Severe HypertriglyceridemiaCompletedNCT06347003Phase 3
• Study of ARO-CFB in Adult Healthy VolunteersCompletedNCT06209177Phase 1
• Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS)WithdrawnNCT05949294Phase 1
• Study of ARO-RAGE in Healthy SubjectsCompletedNCT05533294Phase 1
• Study of ARO-APOC3 in Adults With DyslipidemiaCompletedNCT05413135Phase 2
• Study of ARO-RAGE in Healthy Subjects and Patients With Inflammatory Lung DiseaseCompletedNCT05276570Phase 1/2
• Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal DiseaseCompletedNCT05083364Phase 1/2
• Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell CarcinomaCompletedNCT04169711Phase 1
• Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)CompletedNCT03783377Phase 1
• Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic PatientsCompletedNCT03747224Phase 1
• Study of ARO-AAT in Normal Adult VolunteersCompletedNCT03362242Phase 1
• Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin LevelsWithdrawnNCT02900183Phase 2
• Study of ARC-520 in Patient With Chronic Hepatitis B VirusWithdrawnNCT02349126Phase 2
• Safety and Tolerability Study of ARC-520 in Healthy VolunteersCompletedNCT01872065Phase 1
• Safety Study of CALAA-01 to Treat Solid Tumor CancersTerminatedNCT00689065Phase 1

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