Amgen: Vasculitis trials

The registry lists 10 Vasculitis studies with Amgen as lead sponsor. 0 are open to participants now and 3 have results posted.

Phase 1 5Phase 2 2Phase 3 2No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated VasculitisCompletedNCT02994927Phase 3Results posted
• Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated VasculitisCompletedNCT02222155Phase 2Results posted
• A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated VasculitisCompletedNCT01363388Phase 2Results posted
• Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.Active, not recruitingNCT06321601Phase 3
• A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy ParticipantsCompletedNCT06004960Phase 1
• A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant MedicationsCompletedNCT06004947Phase 1
• A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168CompletedNCT05988021Phase 1
• A Study of CCX168 in Japanese and Caucasian Healthy Adult MalesCompletedNCT05988008Phase 1
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CCX168 in Healthy ParticipantsCompletedNCT05984251Phase 1
• Post-Marketing Surveillance Study of OTEZLACompletedNCT03284879