Amgen: Asthma trials

The registry lists 13 Asthma studies with Amgen as lead sponsor. 1 are open to participants now and 4 have results posted.

Phase 1 7Phase 2 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese VolunteersRecruitingNCT07745907Phase 1
• Study of Efficacy and Safety of Brodalumab Compared With Placebo in Adults With Inadequately Controlled Asthma With High Bronchodilator ReversibilityTerminatedNCT01902290Phase 2Results posted
• Double-blind, Multiple Dose Study of Tezepelumab (AMG 157) in Adults With Mild Atopic AsthmaCompletedNCT01405963Phase 1Results posted
• A Study to Evaluate the Dosing of AMG 827 for Subjects With Inadequately Controlled AsthmaCompletedNCT01199289Phase 2Results posted
• A New Modified-release Tablet Formulation of Prednisone (Lodotra®) in Patients With Nocturnal AsthmaCompletedNCT00686335Phase 2Results posted
• A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate AsthmaActive, not recruitingNCT06637371Phase 1
• A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe AsthmaTerminatedNCT06376045Phase 2
• A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.CompletedNCT01928368Phase 1
• AMG 761 in Adults With AsthmaTerminatedNCT01514981Phase 1
• Safety, Tolerability, and Pharmacokinetics of AMG 827 in Adolescents With AsthmaWithdrawnNCT01395485Phase 1
• Safety, Tolerability, and Pharcodynamics of AMG 853 in Adolescents With AsthmaCompletedNCT01137565Phase 1
• AMG 853 Phase 2 Study in Subjects With Inadequately Controlled AsthmaCompletedNCT01018550Phase 2
• Phase II Study to Evaluate the Efficacy of AMG 317CompletedNCT00436670Phase 2