Abramson Cancer Center at Penn Medicine: Breast Neoplasms trials

The registry lists 58 Breast Neoplasms studies with Abramson Cancer Center at Penn Medicine as lead sponsor. 10 are open to participants now and 9 have results posted.

Early Phase 1 2Phase 1 14Phase 2 11No phase 36(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer SurvivorshipRecruitingNCT07655934Not applicable
• A Pilot Trial of "Just ASK™" to Increase Discussions About Breast Cancer Clinical TrialsRecruitingNCT07040891Not applicable
• Safe and Explainable AIRecruitingNCT06694181
• FES BPET-DBT in Newly Diagnosed Breast CancerRecruitingNCT05659797Early Phase 1
• Role of the Immune Environment in Response to Therapy in Breast CancerRecruitingNCT05396612
• CTNNA1 Familial Expansion StudyRecruitingNCT05126290
• ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast CancerRecruitingNCT04523857Phase 2
• [18F] F-GLN by PET/CT in Breast CancerRecruitingNCT03863457Phase 1
• PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast CancerRecruitingNCT02732171Not applicable
• Cardiotoxicity of Cancer Therapy (CCT)Enrolling by invitationNCT01173341
• Increasing Screening for Cancer Using EHR-NudgesCompletedNCT06177795Not applicableResults posted
• Improving Utilization of Supplemental Breast MRI Screening for Women With Extremely Dense BreastsCompletedNCT05787249Not applicableResults posted
• Pilot Study of an NTproBNP Guided Strategy of CardioprotectionCompletedNCT04737265Phase 1/2Results posted
• Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or TrastuzumabCompletedNCT04023110Phase 1Results posted
• CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast CancerActive, not recruitingNCT03032406Phase 2Results posted
• F18 EF5 PET/CT Imaging in Patients With Brain Metastases From Breast CancerCompletedNCT01985971Not applicableResults posted
• APBI Proton Feasibility and Phase II StudyCompletedNCT01839838Phase 1/2Results posted
• Ruxolitinib in Estrogen Receptor Positive Breast CancerCompletedNCT01594216Phase 2Results posted
• Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With CancerCompletedNCT01037790Phase 2Results posted
• Increasing Screening for Cancer Using EHR-Nudges ReplicationCompletedNCT06995703Not applicable
• The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer PatientsCompletedNCT06604247Not applicable
• Effects of Immune Checkpoint Inhibitors on Coronary MicrovasculatureActive, not recruitingNCT06332131
• Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast CancerActive, not recruitingNCT06019988Not applicable
• Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer PredispositionCompletedNCT05721326Not applicable
• RCT of Strategies to Augment Physical Activity in Black and Hispanic Breast and Prostate Cancer Survivors (ALLSTAR)CompletedNCT05176756Not applicable
• Breast Cancer Outreach Among Primary Care PatientsCompletedNCT05089903Not applicable
• Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast CancerActive, not recruitingNCT05078190
• Telehealth Weight Loss Program for Breast Cancer SurvivorsActive, not recruitingNCT04855552Not applicable
• Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast CancerActive, not recruitingNCT04841148Phase 2
• BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade TherapyActive, not recruitingNCT04454528Phase 1/2
• Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion StudyCompletedNCT04361240
• HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast CancerCompletedNCT03685331Phase 1
• Gedatolisib, Hydroxychloroquine or the Combination for Prevention of Recurrent Breast Cancer ("GLACIER")WithdrawnNCT03400254Phase 1/2
• Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Breast CancerActive, not recruitingNCT03083288Phase 1
• Imaging of in Vivo Sigma-2 Receptor Expression With 18F-ISO-1 Positron Emission Tomography in Metastatic Breast CancerTerminatedNCT03057743
• Surveillance Markers of Utility for Recurrence After Neoadjuvant Chemotherapy for Breast CancerCompletedNCT02830282
• The Breast Program - Translational Cancer ResourceActive, not recruitingNCT02798341
• Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic CancersCompletedNCT02639026Phase 1
• Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium TrialActive, not recruitingNCT02603341Not applicable
• A Trial of Ribocilcib (LEE011) and Weekly Paclitaxel in Patients With Rb+ Advanced Breast CancerCompletedNCT02599363Phase 1
• Study on Breast Cancer Patient Perspectives of ExerciseCompletedNCT02559362
• DC Vaccine for Patients With Ductal Carcinoma In SituCompletedNCT02061332Phase 1/2
• Yoga for Breast CancerCompletedNCT01985945Not applicable
• Multi-peptide Vaccine With Basilixumab for Breast CancerCompletedNCT01660529Early Phase 1
• PD0332991/Paclitaxel in Advanced Breast CancerCompletedNCT01320592Phase 1
• The Effects of Radiation in Reconstructed BreastsCompletedNCT01292772
• BCRL Prevention PilotCompletedNCT01166672
• Physical Functional Side Effects of Taxane Chemotherapy for Breast CancerCompletedNCT01153282
• Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast CancerTerminatedNCT01019512Not applicable
• Positron Emission Tomography in Monitoring Treatment Response in Women With Newly Diagnosed Breast CancerWithdrawnNCT01018251Not applicable
• Visualization of the Effect of Acupuncture on Brain Serotonin in Breast Cancer SurvivorsCompletedNCT01018108Phase 1
• Acupuncture in Treating Women With Stage I, Stage II, or Stage III Breast Cancer With Aromatase Inhibitor-Related Joint PainCompletedNCT01013337Not applicable
• Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast CancerCompletedNCT00892515Not applicable
• Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast CancerCompletedNCT00599989Not applicable
• Bevacizumab and Abraxane as Second-line Therapy in Triple Negative Metastatic Breast CancerCompletedNCT00472693Phase 2
• Vaccine Plus Montanide ISA-51 and Sargramostim in Treating Patients With Stage IV Breast CancerCompletedNCT00079157Phase 1
• MRI for Detecting Cancer in Women Who Are at High Risk of Developing Breast CancerCompletedNCT00003736Not applicable
• MRI to Detect Breast Tumors in WomenCompletedNCT00003302Not applicable