AbbVie: Hypertension trials

The registry lists 79 Hypertension studies with AbbVie as lead sponsor. 0 are open to participants now and 57 have results posted.

Phase 1 3Phase 2 11Phase 3 26Phase 4 24No phase 18(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04285580Phase 3Results posted
• A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02636946Phase 3Results posted
• Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02507687Phase 3Results posted
• Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02250651Phase 3Results posted
• Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02247804Phase 3Results posted
• Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular HypertensionCompletedNCT02097719Phase 4Results posted
• A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02061683Phase 4Results posted
• A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02020512Phase 4Results posted
• A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02003534Phase 4Results posted
• A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical SettingCompletedNCT01999348Results posted
• An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular HypertensionCompletedNCT01881126Phase 4Results posted
• A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular HypertensionCompletedNCT01863953Phase 2Results posted
• A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical ReasonsCompletedNCT01853085Results posted
• A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT01830140Phase 3Results posted
• A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular HypertensionTerminatedNCT01781962Results posted
• An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering TreatmentsCompletedNCT01735214Results posted
• A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to MonotherapyCompletedNCT01637246Results posted
• A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01632423Results posted
• A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01628614Results posted
• GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to MonotherapyCompletedNCT01628601Results posted
• Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01628588Results posted
• A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)CompletedNCT01594970Phase 4Results posted
• A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01589510Results posted
• Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01568008Results posted
• Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT)CompletedNCT01540370Results posted
• A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular HypertensionCompletedNCT01525173Phase 4Results posted
• Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT01489670Results posted
• Study of the Efficacy and Safety of Nebivolol in Younger Patients (18 - 54 Years)CompletedNCT01415531Phase 4Results posted
• Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01298700Phase 4Results posted
• Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01291108Phase 2Results posted
• Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01253902Phase 4Results posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01241240Phase 3Results posted
• Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT01229462Not applicableResults posted
• Efficacy and Safety Study to Evaluate Combination Therapy With Nebivolol and Lisinopril vs. Placebo and Monotherapy in Patients With Stage 2 Diastolic HypertensionCompletedNCT01218100Phase 4Results posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01217606Phase 3Results posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular HypertensionCompletedNCT01216943Phase 3Results posted
• Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle GlaucomaCompletedNCT01215786Phase 1Results posted
• Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01177098Phase 3Results posted
• Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®CompletedNCT01170884Phase 4Results posted
• Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular HypertensionCompletedNCT01157364Phase 1/2Results posted
• Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01110499Phase 2Results posted
• Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01099774Phase 3Results posted
• Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular HypertensionCompletedNCT01068964Not applicableResults posted
• Nebivolol in Patients With Systolic Stage 2 HypertensionCompletedNCT01057251Phase 4Results posted
• An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension SubjectsCompletedNCT00811564Phase 4Results posted
• Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle GlaucomaCompletedNCT00809848Phase 1/2Results posted
• A Study on the Long-term Efficacy of Nebivolol After Withdrawal of TherapyCompletedNCT00785512Phase 4Results posted
• A Study on the Efficacy and Safety of Nebivolol Monotherapy in Hispanic Hypertensive PatientsCompletedNCT00770861Phase 4Results posted
• Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive PatientsCompletedNCT00744237Phase 4Results posted
• Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension SubjectsCompletedNCT00735449Phase 4Results posted
• Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive PatientsCompletedNCT00734630Phase 4Results posted
• The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting GlucoseCompletedNCT00673790Phase 4Results posted
• The Effect of Nebivolol in Hypertensive Patients With Coronary Artery DiseaseCompletedNCT00673075Phase 4Results posted
• A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive PatientsCompletedNCT00648895Phase 3Results posted
• Study to Evaluate Symptoms in Patients Treated With Nebivolol or Metoprolol Extended-release (ER) for HypertensionTerminatedNCT00547300Phase 3Results posted
• Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT00541242Phase 4Results posted
• A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT00538304Phase 2Results posted
• Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02571712Phase 4
• A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02348476
• Economic Impact of Switching From Metoprolol to Nebivolol for Hypertension TreatmentStatus unknownNCT01758263
• Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01737853
• Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 HypertensionCompletedNCT01508026Phase 3
• Combination of Nebivolol and Valsartan Given as Free Tablets for Stage 1 or Stage 2 HypertensionCompletedNCT01415505Phase 3
• Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionWithdrawnNCT01284166Phase 3
• Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT00822055Phase 4
• Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652496Phase 2
• Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652483Phase 3
• Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652106Phase 3
• Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT00651859Phase 2
• Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension PatientsCompletedNCT00651612Phase 3
• Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal PressureTerminatedNCT00414869Phase 2
• Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00332540Phase 3
• Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00332436Phase 3
• Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00332384Phase 3
• Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00332345Phase 2
• Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular HypertensionCompletedNCT00332072Phase 3
• Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00332059Phase 3
• Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT00300443Phase 2/3
• Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular HypertensionCompletedNCT00168363Phase 3