AbbVie: Carcinoma trials

The registry lists 12 Carcinoma studies with AbbVie as lead sponsor. 0 are open to participants now and 3 have results posted.

Phase 1 7Phase 2 6Phase 3 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid TumorsTerminatedNCT02709889Phase 1/2Results posted
• Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary TumorsCompletedNCT02599324Phase 1/2Results posted
• A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular CarcinomaTerminatedNCT02504099Phase 3Results posted
• A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaCompletedNCT04196283Phase 1
• A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell CarcinomaTerminatedNCT03818542Phase 1
• ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid TumorsCompletedNCT02565758Phase 1
• A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor ReceptorTerminatedNCT02365662Phase 1
• Phase 2 Study of ABT-869 in Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00517920Phase 2
• Study of ABT-869 in Subjects With Advanced Renal Cell Carcinoma Who Have Previously Received Treatment With SunitinibCompletedNCT00486538Phase 2
• Trial of Motexafin Gadolinium and Pemetrexed (Alimta®) for Second Line Treatment in Patients With Non-Small Cell Lung CancerTerminatedNCT00365183Phase 2
• Study of Motexafin Gadolinium for the Treatment of Renal Cell (Kidney) CancerCompletedNCT00134186Phase 2
• A Study of Motexafin Gadolinium (MGd) in Combination With Docetaxel and Cisplatin for Treatment of Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00102505Phase 1