Zotemtegrast clinical trials
Also written LY4268989 and MORF-057.
How each study uses zotemtegrast is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the zotemtegrast studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
4 studies that test it; most in 2025 (2)
| Year | Studies |
|---|---|
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 4 · Other 0
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test zotemtegrast.
- May 2027LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:Phase 2 · Eli Lilly and Company
Studies
Open first, then newest update. How each study uses zotemtegrast is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 4
- LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:RecruitingPhase 2Eli Lilly and CompanyNCT07186101Written as LY4268989
- LY4268989 in Adults With Moderately to Severely Active Ulcerative ColitisRecruitingPhase 2Eli Lilly and CompanyNCT07415044Written as LY4268989
- A Study of LY4268989 (MORF 057) in Healthy ParticipantsActive, not recruitingPhase 1Eli Lilly and CompanyNCT07707375Written as LY4268989
- A Study of LY4268989 (MORF-057) in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT06964776Written as LY4268989