Tyrosine Kinase Inhibitors: all 10,744 studies that test it

Page 99 of 108. Open to participants first (1,949), then studies with results posted, then the rest; newest registration first within each.

• Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Failed Both Imatinib and SunitinibCompletedNCT00718562Phase 2
• A Phase 1 Study of ABT-869 in Subjects With Solid TumorsCompletedNCT00718380Phase 1
• Solid Tumors Using Ixabepilone and DasatinibCompletedNCT00717704Phase 1
• A Phase 1b/2a, Open-Label, Multi-Center Study of Tivozanib (AV-951) in Combination With Paclitaxel in Subjects With Advanced or Metastatic Breast CancerCompletedNCT00717340Phase 1
• Study of Carboplatin/Paclitaxel in Combination With ABT-869 in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00716534Phase 2
• Pre-Surgical Sutent in Renal Cell Carcinoma (RCC)Active, not recruitingNCT00715442Phase 2
• A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell CancerCompletedNCT00715182Phase 1
• A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular CarcinomaCompletedNCT00712855Phase 1
• Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC)CompletedNCT00712790Phase 1/2
• A Study of ARRY-334543 and Capecitabine in Patients With Advanced CancerCompletedNCT00710736Phase 1
• Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)CompletedNCT00708903Phase 1
• Early Prediction of Therapeutic Response to Targeted Therapy in Stage IIIB/IV or Recurrent Lung Cancer PatientsCompletedNCT00708448Phase 1
• Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal CancerCompletedNCT00707889Phase 2
• High-Dose Imatinib for Relapsed/Refractory c-Kit Positive Acute Myelogenous Leukemia (AML)CompletedNCT00707408Phase 2
• Study of Polyphenon E in Addition to Erlotinib in Advanced Non Small Cell Lung CancerTerminatedNCT00707252Phase 1
• Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid TumorsWithdrawnNCT00704392Phase 1
• AZD0530 Study 21 - Phase I Study in Patients With Solid TumoursCompletedNCT00704366Phase 1
• Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid TumorsCompletedNCT00703638Phase 1
• Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00703365Phase 2
• Study of Combination Therapy of Carboplatin -Gemcitabine Plus Bevacizumab Beyond Progression in Patients With Locally Advanced and/or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Not Received Prior Systemic TherapyCompletedNCT00702975Phase 2
• Study of Oral Vinorelbine and Erlotinib in Non-Small Cell Lung CancerCompletedNCT00702182Phase 1
• Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced MalignanciesCompletedNCT00697632Phase 1
• Sorafenib in Hormone Naïve Biochemical Recurrence of Prostate CancerWithdrawnNCT00694291Phase 2
• Lapatinib and Circulating Tumor Cells in Breast CancerCompletedNCT00694252Phase 2
• Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid TumorsCompletedNCT00692640Phase 1
• Pilot Study of Curcumin Formulation and Ashwagandha Extract in Advanced OsteosarcomaStatus unknownNCT00689195Phase 1/2
• Fulvestrant With or Without Lapatinib and/or Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer That Progressed After Previous Aromatase Inhibitor TherapyStatus unknownNCT00688194Phase 3
• Safety Study of FP-1039 To Treat CancerCompletedNCT00687505Phase 1
• Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT00686218Phase 1
• Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal CancerStatus unknownNCT00686114Phase 3
• Imatinib Mesylate in Treating Patients With Unresectable or Metastatic Gastrointestinal Stromal TumorStatus unknownNCT00685828Phase 3
• Postoperative Radiotherapy Plus Iressa or Radiotherapy Plus Cisplatin and Iressa for Advanced Head & Neck CancerCompletedNCT00681967Phase 1
• Dose Escalation Study With Zactima and Chemotherapy in Metastatic Pancreas CarcinomaCompletedNCT00681798Phase 1
• Safety Study of Oral MGCD265 Administered With Interruption to Subjects With Advanced MalignanciesCompletedNCT00679133Phase 1
• A Phase I, Open-label, Study of Pazopanib in Combination With Gemcitabine and Gemcitabine Plus Cisplatin for Advanced Solid TumorsCompletedNCT00678977Phase 1
• Erlotinib Versus Carboplatin/Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)Status unknownNCT00678964Phase 2
• Study Testing the Biologic Activity and Safety of a Immunotherapeutic in Patients With Newly Diagnosed Advanced Stage Kidney Cancer in Combination With a Marketed Renal Cell Carcinoma TreatmentCompletedNCT00678119Phase 2
• A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.CompletedNCT00676299Phase 1
• Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver FunctionCompletedNCT00674024Phase 1
• Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous TreatmentCompletedNCT00673569Phase 2
• First-Line Gemcitabine Chemotherapy With Our Without Sunitinib In Advanced or Metastatic Pancreatic CancerCompletedNCT00673504Phase 2
• PH I SRC Kinase, Dasatinib Combo Paclitaxel & Carboplatin in Pts w Ovarian, Peritoneal, & Tubal CancerCompletedNCT00672295Phase 1
• Absorption, Distribution, Metabolism and Excretion (ADME) Study of TKI258 in Patients With Advanced Solid MalignanciesCompletedNCT00669097Phase 1
• CEP-701 (Lestaurtinib) in MyelofibrosisStatus unknownNCT00668421Phase 1/2
• Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and LeukemiaCompletedNCT00665990Phase 1
• Sorafenib Gastric Cancer Asian Phase I StudyCompletedNCT00663741Phase 1
• Efficacy of Erlotinib for Brain Metastasis of Non-Small Cell Lung CancerStatus unknownNCT00663689Phase 2
• Sunitinib in Patients With Renal Cells Carcinoma Metastasic or Locally Avanced in Patients Not Candidates to Curative Previous NefrectomyCompletedNCT00663559Phase 2
• Dasatinib and Lapatinib Ditolsylate in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By SurgeryCompletedNCT00662636Phase 1
• Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT00662506Phase 1/2
• BAY43-9006 Phase II Study for Renal Cell CarcinomaCompletedNCT00661375Phase 2
• Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to GleevecCompletedNCT00661180Phase 2
• Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological MalignanciesCompletedNCT00660920Phase 1
• Study of GemOx and Vandetanib in Advanced Solid MalignancyCompletedNCT00660725Phase 1
• Study of Tivozanib (AV-951) Plus FOLFOX6 in Subjects With Advanced Colorectal Cancer and Other Gastrointestinal CancersCompletedNCT00660153Phase 1
• Evaluation of KX2-391 in Patients With Advanced MalignanciesCompletedNCT00658970Phase 1
• A Dose-Escalation Study of ENMD-2076 Administered Orally to Patients With Advanced CancerCompletedNCT00658671Phase 1
• Bioequivalence Study of ARQ 197 Amorphous and Crystalline Polymorphs A and B in Normal Healthy VolunteersCompletedNCT00658554Phase 1
• Extension Program for Bay 43-9006CompletedNCT00657254Phase 2
• APRiCOT-B: Study to Evaluate Apricoxib in Combination With Lapatinib and Capecitabine in the Treatment of HER2/Neu+ Breast Cancer (TP2001-202)TerminatedNCT00657137Phase 2
• Everolimus and Vatalanib in Treating Patients With Advanced Solid TumorsCompletedNCT00655655Phase 1
• Dasatinib in Resectable Malignant Pleural MesotheliomaCompletedNCT00652574Phase 1
• A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) GenotypeCompletedNCT00651638Phase 1
• A Safety and Dose-finding Study of JNJ-38877605 in Patients With Advanced or Refractory Solid Tumors.TerminatedNCT00651365Phase 1
• Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast CancerCompletedNCT00650910Phase 1
• A Study of ARRY-380 in Patients With Advanced HER2+ CancerCompletedNCT00650572Phase 1
• Phase 2 Study of ABT-869 in Combination With Paclitaxel Versus Paclitaxel Alone to Treat Metastatic Breast CancerCompletedNCT00645177Phase 2
• Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal CancerCompletedNCT00640471Phase 3
• Tarceva Italian Lung Optimization tRialStatus unknownNCT00637910Phase 3
• A Study of ARRY-334543 in Patients With Advanced CancerCompletedNCT00637702Phase 1
• Study of AZD8931 in Patients With Advanced Solid MalignanciesCompletedNCT00637039Phase 1
• Ph II Early BC Pre-Surgical Biologic StudyCompletedNCT00637026Phase 2
• Open-Label Extension of Other SZ1839 (Iressa) TrialsCompletedNCT00635973Phase 3
• Open Label Trial to Assess Iressa in Prostate Cancer PatientsCompletedNCT00635856Phase 2
• Phase I Study of Vorinostat and Sorafenib in Advanced CancerCompletedNCT00635791Phase 1
• Gemcitabine With or Without Capecitabine and/or Radiation Therapy or Gemcitabine With or Without Erlotinib in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by SurgeryCompletedNCT00634725Phase 3
• Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor TypesCompletedNCT00633789Phase 2
• Study of Apatinib as an Inhibitor of Tumor AngiogenesisStatus unknownNCT00633490Phase 1
• Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) InhibitorCompletedNCT00633295Phase 2
• IRESSA™ (Gefitinib) in Breast Cancer PatientsCompletedNCT00632723Phase 2
• Clinical Trial of Sutent to Treat Metastatic MelanomaCompletedNCT00631618Phase 2
• Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate CancerCompletedNCT00631527Phase 1
• A Dose-escalation Study of the Safety and Tolerability of Orally Administered TG101348 in Patients With MyelofibrosisCompletedNCT00631462Phase 1
• Dose Escalation Trial of Neoadjuvant Sorafenib and Concurrent Sorafenib, Cisplatin and Radiation in Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN)WithdrawnNCT00627835Phase 1
• Sunitinib Before or After Surgery in Treating Patients With Metastatic Kidney CancerStatus unknownNCT00626509Phase 2
• Combined Treatment of Sorafenib and Pegylated Interferon α2b in Stage IV Metastatic MelanomaCompletedNCT00623402Phase 2
• Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.TerminatedNCT00622479Phase 1
• Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid TumoursCompletedNCT00621725Phase 1
• Phase I Safety and Tolerability Study of Cediranib (RECENTIN™, AZD2171) in Combination With Chemo in First Line Lung Cancer PatientsCompletedNCT00621361Phase 1
• Sunitinib as a Second-line Treatment for Patients With Recurrent Small Cell Lung CancerCompletedNCT00620347Phase 2
• Induction Chemotherapy Followed by CCRT According to EGFR Mutation Status in NSCLC IIIStatus unknownNCT00620269Phase 2
• Study of Sorafenib and Docetaxel in Metastatic Prostate CancerCompletedNCT00619996Phase 2
• Study of Sorafenib and Infusional 5-Fluorouracil in Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00619541Phase 2
• A Phase I Study Of Pazopanib With Either Erlotinib Or Pemetrexed In Patients With Advanced Solid TumorsCompletedNCT00619424Phase 1
• Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00618501Phase 2
• TACE and Sorafenib for Advanced Hepatocellular Carcinoma (HCC)TerminatedNCT00618384Phase 2
• A Study To Find The Best Doses Of SU011248 (Sunitinib) And Capecitabine When These Drugs Are Administered TogetherCompletedNCT00618124Phase 1
• Combination of Recombinant Human IL-21 (rIL-21) and Sunitinib in Stage IV Renal Cell Carcinoma PatientsCompletedNCT00617253Phase 2
• Gefitinib in Treating Patients With Stage IIIA Non-Small Cell Lung CancerStatus unknownNCT00616499Phase 2
• Erlotinib as 1st Line Treatment in NSCLC Stage IIIB/IVCompletedNCT00615758Phase 2

← Tyrosine Kinase Inhibitors overview