Semaglutide: beside a new treatment under test

75 studies: a new drug, cell therapy or vaccine is what the study tests. Page 1 of 1. Open to participants first (15), then studies with results posted, then the rest; newest registration first within each.

• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide MedicationRecruitingNCT07855133Phase 1Report a problem
• Evaluate the Safety and Tolerability of Multiple Doses of JMT206 Injection in Obese ParticipantsRecruitingNCT07840729Phase 1Report a problem
• Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to CagrisemaRecruitingNCT07817251Phase 3Report a problem
• Evaluating the Efficacy and Safety of LUM-201 Plus Semaglutide Versus Semaglutide Plus Placebo in Older Obese AdultsNot yet recruitingNCT07754045Phase 2Report a problem
• Fecal Microbiota Transplantation (FMT) Combined With Calorie-Restricted Diet and Semaglutide in Patients With Obesity and Type 2 DiabetesNot yet recruitingNCT07599046Not applicableReport a problem
• Efficacy, Safety, and Tolerability of CS0159 Combined With Semaglutide in MAFLD Patients With Obesity and T2DMNot yet recruitingNCT07570810Not applicableReport a problem
• A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightRecruitingNCT07564414Phase 3Report a problem
• Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)RecruitingNCT07527195Phase 1Report a problem
• Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based TherapyRecruitingNCT07502508Phase 2Report a problem
• Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.Not yet recruitingNCT07411378Phase 2Report a problem
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiabetesRecruitingNCT07282613Phase 3Report a problem
• A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightRecruitingNCT07253285Phase 3Report a problem
• A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)RecruitingNCT07101939Phase 2Report a problem
• A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideRecruitingNCT06897475Phase 2Report a problem
• PEG-rhGH and Semaglutide Combination Therapy in Non-Diabetic Obese AdultsNot yet recruitingNCT06863363Phase 4Report a problem
• Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in ObesityCompletedNCT06771115Phase 2Results postedReport a problem
• Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or ObeseCompletedNCT05616013Phase 2Results postedReport a problem
• A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)CompletedNCT05259033Phase 3Results postedReport a problem
• A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 DiabetesCompletedNCT05144984Phase 2Results postedReport a problem
• Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 DiabetesCompletedNCT04982575Phase 2Results postedReport a problem
• A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With ObesityCompletedNCT04969939Phase 2Results postedReport a problem
• Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH)CompletedNCT03987074Phase 2Results postedReport a problem
• A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or ObesityActive, not recruitingNCT07724340Phase 2Report a problem
• MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) TrialActive, not recruitingNCT07505303Phase 2Report a problem
• A Study of CS060380 Tablets in Patients With MASH and ObesityActive, not recruitingNCT07466017Phase 2Report a problem
• Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight LossActive, not recruitingNCT07446998Phase 2Report a problem
• A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightWithdrawnNCT07357766Phase 3Report a problem
• A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesWithdrawnNCT07357740Phase 2Report a problem
• Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2)CompletedNCT07220629Phase 2Report a problem
• A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietActive, not recruitingNCT07184086Phase 1Report a problem
• A Ph2 Study to Evaluate the Safety, Efficacy and Tolerability of HT-6184 and Semaglutide in Obese Participants With T2DMWithdrawnNCT07172867Phase 2Report a problem
• Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide TreatmentCompletedNCT07171723Early Phase 1Report a problem
• A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 DiabetesActive, not recruitingNCT07087795Phase 1Report a problem
• A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termActive, not recruitingNCT07011667Phase 3Report a problem
• A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Combination With SemaglutideCompletedNCT06972992Phase 1Report a problem
• A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyCompletedNCT06797869Phase 2Report a problem
• A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityActive, not recruitingNCT06780449Phase 3Report a problem
• A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or ObesityCompletedNCT06716307Phase 1Report a problem
• A Study of Enlicitide Decanoate (MK-0616) and Semaglutide in Healthy Adult Participants (MK-0616-023)CompletedNCT06699329Phase 1Report a problem
• Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs PlaceboActive, not recruitingNCT06577090Phase 2Report a problem
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothCompletedNCT06534411Phase 3Report a problem
• Efficacy and Safety of CS0159 Combined With Semaglutide in MASH Patients With Obesity and T2DMCompletedNCT06492330Not applicableReport a problem
• Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesCompletedNCT06403761Phase 1Report a problem
• Study That Tests AD109 in Patients Taking GLP-1 DrugsCompletedNCT06400615Phase 2Report a problem
• A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightCompletedNCT06388187Phase 3Report a problem
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseCompletedNCT06323174Phase 3Report a problem
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminCompletedNCT06323161Phase 3Report a problem
• A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass PreservationCompletedNCT06299098Phase 2Report a problem
• A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightCompletedNCT06289504Phase 1Report a problem
• Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight MgmtCompletedNCT06282458Phase 2Report a problem
• A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)CompletedNCT06269107Phase 3Report a problem
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06221969Phase 3Report a problem
• A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightCompletedNCT06207877Phase 1Report a problem
• A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightCompletedNCT06131437Phase 3Report a problem
• A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboCompletedNCT06131372Phase 2Report a problem
• A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06065540Phase 3Report a problem
• A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightCompletedNCT05996848Phase 3Report a problem
• A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF TherapyCompletedNCT05984238Not applicableReport a problem
• A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightCompletedNCT05813925Phase 3Report a problem
• A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate FormulationsCompletedNCT05766709Phase 1Report a problem
• A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906CompletedNCT05751226Phase 1Report a problem
• REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsActive, not recruitingNCT05669755Phase 3Report a problem
• A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose WeightActive, not recruitingNCT05567796Phase 3Report a problem
• A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese MenCompletedNCT05498610Phase 1Report a problem
• A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or TogetherCompletedNCT05435677Phase 1Report a problem
• A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose WeightCompletedNCT05394519Phase 3Report a problem
• A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy PeopleCompletedNCT05046873Phase 1Report a problem
• Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)CompletedNCT05016882Phase 2Report a problem
• A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3)CompletedNCT05013229Phase 3Report a problem
• A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Japanese MenCompletedNCT04878406Phase 1Report a problem
• First Research Study to Look at How Two Medicines, NNC0480-0389 and Semaglutide, Work Together in Healthy People, in People With High Body Weight and in People With DiabetesCompletedNCT04259801Phase 1Report a problem
• A Research Study to Look at How Insulin 287 and Semaglutide Work in the Body of People With Type 2 Diabetes When Taken Alone or TogetherCompletedNCT03789578Phase 1Report a problem
• A Research Study of NNC0165-1875 Alone or Together With Semaglutide in People Who Are Overweight or ObeseCompletedNCT03707990Phase 1Report a problem
• A Research Study of How NNC0174-0833 Taken With Semaglutide Works in People Who Are Overweight or ObeseCompletedNCT03600480Phase 1Report a problem
• A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or ObeseCompletedNCT03574584Phase 1Report a problem

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