Protein Kinase Inhibitors: all 15,766 studies that test it
Page 144 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform NeurofibromasCompletedNCT00727233Phase 1
- Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line ChemotherapyTerminatedNCT00727207Phase 2
- Phase I Trial of Oral PX-866CompletedNCT00726583Phase 1
- A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple MyelomaCompletedNCT00725634Phase 1
- Effect of Rifampin on Bosutinib When Both Are Given to Healthy PeopleCompletedNCT00725426Phase 1
- Erlotinib and Sorafenib in Chemonaive Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerStatus unknownNCT00722969Phase 2
- A Phase I, Open-label, Study of Pazopanib in Combination With Epirubicin or Doxorubicin for Advanced Solid TumorsCompletedNCT00722293Phase 1
- Study to Determine the Effect of a High-Fat Meal on the Relative Bioavailability and Pharmacokinetics of a Single Dose of Bosutinib Administered Orally to Healthy SubjectsCompletedNCT00721474Phase 1
- A Phase I Trial of Bortezomib and SunitinibCompletedNCT00720148Phase 1
- A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid MalignanciesCompletedNCT00719836Phase 1/2
- Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Failed Both Imatinib and SunitinibCompletedNCT00718562Phase 2
- A Phase 1 Study of ABT-869 in Subjects With Solid TumorsCompletedNCT00718380Phase 1
- Solid Tumors Using Ixabepilone and DasatinibCompletedNCT00717704Phase 1
- A Phase 1b/2a, Open-Label, Multi-Center Study of Tivozanib (AV-951) in Combination With Paclitaxel in Subjects With Advanced or Metastatic Breast CancerCompletedNCT00717340Phase 1
- Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal FailureCompletedNCT00716573Phase 4
- Study of Carboplatin/Paclitaxel in Combination With ABT-869 in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00716534Phase 2
- Pre-Surgical Sutent in Renal Cell Carcinoma (RCC)Active, not recruitingNCT00715442Phase 2
- A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell CancerCompletedNCT00715182Phase 1
- A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of ChemotherapyCompletedNCT00714025Phase 2
- A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular CarcinomaCompletedNCT00712855Phase 1
- Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC)CompletedNCT00712790Phase 1/2
- Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular DegenerationTerminatedNCT00712491Phase 1/2
- A Study of ARRY-334543 and Capecitabine in Patients With Advanced CancerCompletedNCT00710736Phase 1
- Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic MalignanciesCompletedNCT00710528Phase 1
- Study to Assess the Effect of Dosing AZD6244 HydSulfate in the Presence and Absence of Food in Patients With Advanced Solid MalignanciesCompletedNCT00710515Phase 1
- Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)CompletedNCT00708903Phase 1
- Study of Rapamycin Plus Ketoconazole in Advanced CancersCompletedNCT00708591Phase 1
- Early Prediction of Therapeutic Response to Targeted Therapy in Stage IIIB/IV or Recurrent Lung Cancer PatientsCompletedNCT00708448Phase 1
- Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal CancerCompletedNCT00707889Phase 2
- High-Dose Imatinib for Relapsed/Refractory c-Kit Positive Acute Myelogenous Leukemia (AML)CompletedNCT00707408Phase 2
- Study of Polyphenon E in Addition to Erlotinib in Advanced Non Small Cell Lung CancerTerminatedNCT00707252Phase 1
- Rapamycin in Advanced CancersCompletedNCT00707135Phase 1
- Phase II Study of BI 2536 in Prostate CancerCompletedNCT00706498Phase 2
- Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid TumorsWithdrawnNCT00704392Phase 1
- AZD0530 Study 21 - Phase I Study in Patients With Solid TumoursCompletedNCT00704366Phase 1
- A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant GliomasCompletedNCT00704080Phase 1
- A Multi-Center Phase I Study of Intravenous Deforolimus (AP23573, MK-8669) Administered QDX5 Every Other Week in Pediatric Patients With Advanced Solid Tumors (8669-028)(COMPLETED)CompletedNCT00704054Phase 1
- Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial CancersCompletedNCT00703807Phase 1
- Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid TumorsCompletedNCT00703638Phase 1
- Phase I Study of Docetaxel and Temsirolimus in Resistant Solid MalignanciesCompletedNCT00703625Phase 1
- Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00703365Phase 2
- Phase I Study of DOXIL and Temsirolimus in Resistant Solid MalignanciesCompletedNCT00703170Phase 1
- Study of Combination Therapy of Carboplatin -Gemcitabine Plus Bevacizumab Beyond Progression in Patients With Locally Advanced and/or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Not Received Prior Systemic TherapyCompletedNCT00702975Phase 2
- Study of Oral Vinorelbine and Erlotinib in Non-Small Cell Lung CancerCompletedNCT00702182Phase 1
- BI 2536 Infusional Treatment in Patients Over 60 Years of Age With Refractory or Relapsed Acute Myeloid LeukaemiaCompletedNCT00701766Phase 2
- BI 811283 in Various Solid TumoursCompletedNCT00701324Phase 1
- Study of Oral OSI-027 in Patients With Advanced Solid Tumors or LymphomaCompletedNCT00698243Phase 1
- Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced MalignanciesCompletedNCT00697632Phase 1
- Phase I Open-Label, Dose-Escalation Study of GSK1059615 in Patients With Solid Tumors or LymphomaTerminatedNCT00695448Phase 1
- Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart TransplantStatus unknownNCT00695344Phase 4
- Sorafenib in Hormone Naïve Biochemical Recurrence of Prostate CancerWithdrawnNCT00694291Phase 2
- Lapatinib and Circulating Tumor Cells in Breast CancerCompletedNCT00694252Phase 2
- Study of Ridaforolimus (MK-8669) in Participants With Solid Tumors (MK-8669-003)(COMPLETED)CompletedNCT00694083Phase 1
- A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus CorticosteroidsStatus unknownNCT00693446Phase 4
- Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple MyelomaCompletedNCT00693433Phase 1
- Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid TumorsCompletedNCT00692640Phase 1
- Pilot Study of Curcumin Formulation and Ashwagandha Extract in Advanced OsteosarcomaStatus unknownNCT00689195Phase 1/2
- Fulvestrant With or Without Lapatinib and/or Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer That Progressed After Previous Aromatase Inhibitor TherapyStatus unknownNCT00688194Phase 3
- Open-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or LymphomaCompletedNCT00687622Phase 1
- Safety Study of FP-1039 To Treat CancerCompletedNCT00687505Phase 1
- Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT00686218Phase 1
- Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal CancerStatus unknownNCT00686114Phase 3
- Imatinib Mesylate in Treating Patients With Unresectable or Metastatic Gastrointestinal Stromal TumorStatus unknownNCT00685828Phase 3
- Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate CancerWithdrawnNCT00685633Phase 2
- Postoperative Radiotherapy Plus Iressa or Radiotherapy Plus Cisplatin and Iressa for Advanced Head & Neck CancerCompletedNCT00681967Phase 1
- Dose Escalation Study With Zactima and Chemotherapy in Metastatic Pancreas CarcinomaCompletedNCT00681798Phase 1
- Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney TransplantationCompletedNCT00681213Phase 4
- Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast CancerCompletedNCT00680758Phase 1
- Safety Study of Oral MGCD265 Administered With Interruption to Subjects With Advanced MalignanciesCompletedNCT00679133Phase 1
- A Phase I, Open-label, Study of Pazopanib in Combination With Gemcitabine and Gemcitabine Plus Cisplatin for Advanced Solid TumorsCompletedNCT00678977Phase 1
- Erlotinib Versus Carboplatin/Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)Status unknownNCT00678964Phase 2
- Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic CancerCompletedNCT00678769Phase 1
- Study Testing the Biologic Activity and Safety of a Immunotherapeutic in Patients With Newly Diagnosed Advanced Stage Kidney Cancer in Combination With a Marketed Renal Cell Carcinoma TreatmentCompletedNCT00678119Phase 2
- A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.CompletedNCT00676299Phase 1
- Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By SurgeryTerminatedNCT00674414Phase 2
- Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver FunctionCompletedNCT00674024Phase 1
- Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous TreatmentCompletedNCT00673569Phase 2
- First-Line Gemcitabine Chemotherapy With Our Without Sunitinib In Advanced or Metastatic Pancreatic CancerCompletedNCT00673504Phase 2
- PH I SRC Kinase, Dasatinib Combo Paclitaxel & Carboplatin in Pts w Ovarian, Peritoneal, & Tubal CancerCompletedNCT00672295Phase 1
- Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory LymphomaTerminatedNCT00671112Phase 1
- A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) TransplantationCompletedNCT00670423Phase 1
- Absorption, Distribution, Metabolism and Excretion (ADME) Study of TKI258 in Patients With Advanced Solid MalignanciesCompletedNCT00669097Phase 1
- CEP-701 (Lestaurtinib) in MyelofibrosisStatus unknownNCT00668421Phase 1/2
- Rapamycin Plus Bevacizumab in Advanced CancersCompletedNCT00667485Phase 1
- Study to Investigate AKT Inhibitor GSK690693 in Subjects With Relapsed or Refractory Hematologic MalignanciesWithdrawnNCT00666081Phase 1
- Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and LeukemiaCompletedNCT00665990Phase 1
- A Study of ARRY-371797 in Subjects Undergoing Third Molar ExtractionCompletedNCT00663767Phase 2
- Sorafenib Gastric Cancer Asian Phase I StudyCompletedNCT00663741Phase 1
- Efficacy of Erlotinib for Brain Metastasis of Non-Small Cell Lung CancerStatus unknownNCT00663689Phase 2
- Sunitinib in Patients With Renal Cells Carcinoma Metastasic or Locally Avanced in Patients Not Candidates to Curative Previous NefrectomyCompletedNCT00663559Phase 2
- Dasatinib and Lapatinib Ditolsylate in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By SurgeryCompletedNCT00662636Phase 1
- Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT00662506Phase 1/2
- BAY43-9006 Phase II Study for Renal Cell CarcinomaCompletedNCT00661375Phase 2
- Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to GleevecCompletedNCT00661180Phase 2
- Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological MalignanciesCompletedNCT00660920Phase 1
- Study of GemOx and Vandetanib in Advanced Solid MalignancyCompletedNCT00660725Phase 1
- Study of Tivozanib (AV-951) Plus FOLFOX6 in Subjects With Advanced Colorectal Cancer and Other Gastrointestinal CancersCompletedNCT00660153Phase 1
- Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or LymphomaCompletedNCT00659568Phase 1
- Evaluation of KX2-391 in Patients With Advanced MalignanciesCompletedNCT00658970Phase 1
- A Dose-Escalation Study of ENMD-2076 Administered Orally to Patients With Advanced CancerCompletedNCT00658671Phase 1