Protein Kinase Inhibitors: all 15,278 studies that test it
Page 112 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.
- Gilotrif (Afatinib) in Advanced Non-Small Cell Lung Cancer Patients Pre-treated With Erlotinib or GefitinibCompletedNCT02747953Phase 2
- Lucitanib (E3810) in Patients With Advanced Cancer and FGFR, VEGFR, or PDGFR Pathway AberrationsWithdrawnNCT02747797Phase 2
- Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors With Sorafenib in Combination With IrinotecanWithdrawnNCT02747537Phase 2
- Phase I Trial of BAY1251152 for Advanced Blood CancersCompletedNCT02745743Phase 1
- D-ALBA Frontline Sequential Dasatinib and Blinatumomab in Adult Philadelphia Positive Acute Lymphoblastic LeukemiaStatus unknownNCT02744768Phase 2
- Cryotherapy Combine Icotinib for Advanced NSCLC TreatmentCompletedNCT02744664Phase 4
- Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Duvortuxizumab (JNJ-64052781) Plus Ibrutinib in LymphomaWithdrawnNCT02743546Phase 1
- Trial Ruxolitinib and Peg-interferon Alpha-2a Combination in Patients With Primary Myelofibrosis RUXOPegCompletedNCT02742324Phase 1/2
- A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast CancerCompletedNCT02742051Phase 2
- Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase InhibitorActive, not recruitingNCT02738866Phase 2
- Alternating Icotinib and Chemotherapy for Advanced Non-small Cell Lung Cancer With EGFR MutationStatus unknownNCT02737774Phase 2
- Study of CG200745 PPA in Combination With Gemcitabine and Erlotinib for Advanced Pancreatic CancerStatus unknownNCT02737228Phase 1/2
- Safety and Efficacy of Saracatinib In Subjects With LymphangioleiomyomatosisTerminatedNCT02737202Phase 2
- Intracranial Activity of AZD9291 (TAGRISSO) in Advanced EGFRm NSCLC Patients With Asymptomatic Brain MetastasesStatus unknownNCT02736513Phase 2
- Use of Regorafenib in Recurrent Epithelial Ovarian CancerCompletedNCT02736305Phase 2
- A Study of Acalabrutinib in Combination With Rituximab Versus Ibrutinib Versus Acalabrutinib in Subjects With Relapsed or Refractory Mantle Cell LymphomaWithdrawnNCT02735876Phase 3
- A Study of Galunisertib (LY2157299) and Durvalumab (MEDI4736) in Participants With Metastatic Pancreatic CancerCompletedNCT02734160Phase 1
- Mechanism of Sorafenib Resistance in Patients With Advanced Hepatocellular CarcinomaStatus unknownNCT02733809Phase 4
- The Efficacy and Safety of Apatinib Combined With Etoposide in Heavily Pretreated Advanced Non-small Cell Lung CancerStatus unknownNCT02733107Phase 2
- Study of Apatinib in Patients With Differentiated Thyroid CancerCompletedNCT02731352Phase 2
- Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)Active, not recruitingNCT02730923Phase 1/2
- Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell LymphomaWithdrawnNCT02729961Phase 1/2
- First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid TumorsCompletedNCT02729298Phase 1
- Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCTTerminatedNCT02728700Phase 1
- A Study of Second-line Treatment With Apatinib After TACE in Advanced Hepatocellular Carcinoma PatientsStatus unknownNCT02727309Phase 1/2
- Apatinib as Second-line Treatment of Advanced Pancreatic CancerStatus unknownNCT02726854Phase 2
- High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain MetastasesStatus unknownNCT02726568Phase 2
- Phase II Study Assessing the Efficacy and Safety of Lenvatinib for Anaplastic Thyroid CancerCompletedNCT02726503Phase 2
- Adjuvant Anti-Recurrence Treatment With Rapamycin on Early-stage HCCCompletedNCT02724332Phase 1
- A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic LeukemiaCompletedNCT02723994Phase 2
- PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)CompletedNCT02723877Phase 1/2
- Pemetrexed and Erlotinib for Metastatic Colorectal CancerCompletedNCT02723578Phase 2
- Midostaurin in Treating Older Patients With Mutated Acute Myeloid Leukemia Post-TransplantWithdrawnNCT02723435Phase 2
- Olmutinib (BI 1482694) ADME StudyCompletedNCT02722161Phase 1
- A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy FailedWithdrawnNCT02722135Phase 1
- Effectiveness of Ursodeoxycholic Acid Use in the Prevention of Gallstone Formation After Sleeve GastrectomyStatus unknownNCT02721862Phase 3
- Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric CancerTerminatedNCT02720926Phase 1
- Safety, Tolerability, and Pharmacokinetics of a Single Oral Dose of SKI-O-703 in Healthy VolunteersCompletedNCT02717988Phase 1
- A Study of Tafetinib in Chinese Patients With Advanced Solid TumorStatus unknownNCT02717741Phase 1
- A Study of TAK-788 in Adults With Non-Small Cell Lung CancerActive, not recruitingNCT02716116Phase 1/2
- Thoracal Radiotherapy and TarcevaTerminatedNCT02714530Phase 2
- Efficacy of Rechallenge With Sunitinib in Metastatic Pancreatic Neuroendocrine Tumor Previously Failed to SunitinibCompletedNCT02713763Phase 2
- A Study of Intermittent Dosing Schedule of Imatinib in Patients With Tyrosine Kinase Inhibitor Refractory GISTsCompletedNCT02712112Phase 2
- A Study of Apatinib Mesylate (YN968D1) 1,000mg in Gastric Cancer Patient Failed to Standard TreatmentCompletedNCT02711969Phase 1
- Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal TherapyCompletedNCT02711007Phase 2/3
- Safety, Tolerability and Relative Bioavailability Study of BMS-986195 in Healthy SubjectsCompletedNCT02705989Phase 1
- A Drug-Drug Interaction Study to Assess the Effect of Trametinib on the Pharmacokinetics of an Oral Contraceptive in Female Patients With Solid TumorsCompletedNCT02705963Phase 1
- Phase Ib/II Trial of coPANlisib in Combination With Trastuzumab in HER2-positive Breast Cancer. (Panther Study)CompletedNCT02705859Phase 1
- Rociletinib Genomic Landscape in Non-small Cell Lung Cancer (NSCLC)WithdrawnNCT02705339Phase 2
- Tarceva With or Without Apatinib in the Advanced Lung AdenocarcinomaStatus unknownNCT02704767Phase 2
- Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid TumorsTerminatedNCT02703571Phase 1
- Treatment Patients With Pulmonary Metastasis of Liver Cancer With Apatinib Combination With TACE: a Clinical StudyStatus unknownNCT02702323Phase 2/3
- Axitinib in Metastatic Renal Cell Carcinoma Patients With Favorable Prognostic FactorsCompletedNCT02700568Phase 2
- A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell LymphomasTerminatedNCT02700022Phase 1
- Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy SubjectsCompletedNCT02699710Phase 1
- A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or CholangiocarcinomaCompletedNCT02699606Phase 2
- Evaluation of Treatment Response With CHOI and RECIST Criteria and CT Texture Analysis in Patients With Metastatic Colorectal Cancer Treated With RegorafenibCompletedNCT02699073Phase 2
- Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal CarcinomaTerminatedNCT02698111Phase 1/2
- Clinical Trial of Apatinib Reverses Chemotherapy-Resistance of Patients With Advanced Gastric CancerStatus unknownNCT02697838Phase 2
- Gossypol Acetic Acid With Lenalidomide and Dexamethasone in Treating Patients With Relapsed Symptomatic Multiple MyelomaCompletedNCT02697344Phase 1
- Trial Twice Daily Application of LEO 124249 Ointment 30 mg/g in Treatment of Mild to Moderate Inverse PsoriasisCompletedNCT02695940Phase 2
- Study of Safety, Efficacy and Pharmacokinetics of CT-707 in Patients With ALK-positive Non-small Cell Lung CancerStatus unknownNCT02695550Phase 1
- Cisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary OriginStatus unknownNCT02695459Phase 2
- A Study to Assess the Absorption, Metabolism, and Routes of Excretion Following Oral Administration of (14C) Radiolabeled JNJ--42756493 to Healthy Male ParticipantsCompletedNCT02692677Phase 1
- Apatinib Plus Docetaxel as 2nd Line Treatment in Patients With Advanced Lung Adenocarcinoma Harboring Wild-type EGFRStatus unknownNCT02691871Phase 1
- Study to Evaluate the Safety and Efficacy of Sunitinib, in Subject With Refractory Solid TumorsCompletedNCT02691793Phase 4
- Study to Evaluate the Safety and Efficacy of Sorafenib, in Subject With Refractory Solid TumorsWithdrawnNCT02691780Not applicable
- Study to Evaluate the Safety and Efficacy of Pazopanib, in Subject With Refractory Solid TumorsCompletedNCT02691767Not applicable
- Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK2269557 Administered Via the ELLIPTA Dry Powder Inhaler to Healthy SubjectsCompletedNCT02691325Phase 1
- A Phase III Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung CancerCompletedNCT02691299Phase 3
- Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia PatientsStatus unknownNCT02690922Phase 4
- Fulvestrant (F)+Placebo vs F+Palbociclib First Line for Postmenopausal Hormone Receptor+ Advanced Breast CancerStatus unknownNCT02690480Phase 2
- A Mass Balance Study to Investigate the Absorption, Metabolism, and Excretion Of [14C] FruquintinibCompletedNCT02689752Phase 1
- Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous LeukemiaActive, not recruitingNCT02689440Phase 2
- Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid TumorsWithdrawnNCT02689336Phase 2
- Study to Assess Various Sunitinib Schedules in Renal Cell CarcinomaStatus unknownNCT02689167Phase 2
- Sequential Regimen of Bendamustin-Debulking Followed by Ofatumumab and Ibrutinib in CLL Patients (CLL2-BIO)CompletedNCT02689141Phase 2
- Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 MutationTerminatedNCT02688907Phase 2
- Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid TumorsCompletedNCT02688881Phase 4
- ExIST Study of LY2157299 (Galunisertib) in Rectal CancerActive, not recruitingNCT02688712Phase 2
- Study of Everolimus as Maintenance Therapy for Metastatic NEC With Pulmonary or Gastroenteropancreatic OriginActive, not recruitingNCT02687958Phase 2
- Safety and Efficiency Study of Pioglitazone in Combination With Imatinib Mesylate to Treat Chronic Myelogenous LeukemiaStatus unknownNCT02687425Phase 2
- Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant RecipientsCompletedNCT02686619Phase 3
- Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast CancerStatus unknownNCT02685657Phase 2
- Imatinib as Pre-operative Anti-Colon Cancer Targeted TherapyTerminatedNCT02685046Phase 2
- Bioavailability Study Of PF-06651600 In Healthy SubjectsCompletedNCT02684760Phase 1
- A Study of SHR6390 in Advanced Solid Tumor PatientsCompletedNCT02684266Phase 1
- A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast CancerCompletedNCT02684032Phase 1
- Study of Apatinib in Metastatic Esophageal CancerStatus unknownNCT02683655Phase 2
- Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant PatientsCompletedNCT02683291Phase 4
- Ibrutinib in Combination With Rituximab in Patients With Indolent Clinical Forms of MCLActive, not recruitingNCT02682641Phase 2
- A Study of Cediranib and Olaparib at Disease Worsening in Ovarian CancerCompletedNCT02681237Not applicable
- Dasatinib in Combination With Chemotherapy for Relapsed or Refractory Core Binding Factor Acute Myeloid LeukemiaWithdrawnNCT02680951Phase 1
- The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell LymphomaCompletedNCT02679196Phase 1
- Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell DiseaseTerminatedNCT02678143Phase 1
- Multicenter Study of Pacritinib Combined With Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)WithdrawnNCT02677948Phase 1/2
- Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant TumorsCompletedNCT02675491Phase 1
- Phase 1 Study of QuizartinibCompletedNCT02675478Phase 1
- To Evaluate the Efficacy and Safety of Rapamycin for Crohn's Disease-related StrictureStatus unknownNCT02675153Not applicable
- A Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid TumorsWithdrawnNCT02674555Phase 1