Protein Kinase Inhibitors: all 15,766 studies that test it
Page 10 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid TumorsRecruitingNCT06952010Phase 1
- Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line InductionNot yet recruitingNCT06951841Phase 4
- A Study of BL-B01D1 and Almonertinib in Patients With Resectable EGFR+ Stage II-IIIB NSCLCRecruitingNCT06951464Phase 2
- Phase 3 Trial of eRapa in Patients With Familial Adenomatous PolyposisRecruitingNCT06950385Phase 3
- Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL TrialRecruitingNCT06948786Phase 2
- Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesRecruitingNCT06948097Phase 1
- A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS MutationsRecruitingNCT06947811Phase 1/2
- Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine TumorsRecruitingNCT06943755Phase 2/3
- Zanubrutinib Combined With BR in the First-line Treatment of Waldenström's MacroglobulinemiaNot yet recruitingNCT06942507Not applicable
- Optimize Immunosuppressive Therapy Using Everolimus and Low-dose Calcineurin Inhibitors in Heart Transplant Patients in KoreaNot yet recruitingNCT06942156Phase 4
- A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast CancerNot yet recruitingNCT06941142Phase 1
- Tirabrutinib Maintenance Versus Placebo in Patients With Primary CNS Lymphoma in Complete Remission (JCOG2104)RecruitingNCT06940791Phase 2
- Interventional Study to Evaluate the Combination of Palbociclib + Sunitinib as a Treatment for Advanced Solid TumorsRecruitingNCT06940349Phase 1/2
- Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple MyelomaRecruitingNCT06940297Phase 2
- Maintenance Zanzalintinib With Etoposide After HDCT in GCTRecruitingNCT06937866Phase 1/2
- Study of ABBV-637 or ABBV-155 With ERAS-801 for People With GlioblastomaRecruitingNCT06934889Phase 1
- Cabozantinib and Nivolumab Among Older Patients With Renal Cell CarcinomaRecruitingNCT06934057Phase 4
- Arsenic Trioxide With MAPK Inhibitors and Chemotherapy for Stage 4/M NeuroblastomaRecruitingNCT06933394Phase 2
- Benmelstobart, Anlotinib and Chemotherapy as First-line Treatment for Extensive-stage Small-cell Lung CancerNot yet recruitingNCT06931145Phase 4
- Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 InhibitorsNot yet recruitingNCT06929325Phase 3
- Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug StudyRecruitingNCT06928272Phase 3
- Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)RecruitingNCT06926634Phase 2
- SHR0302 Combined With PD-1/PD-L1 Inhibition for Treatment naïve or Acquired Resistant to Immunology NSCLCNot yet recruitingNCT06925048Phase 2
- Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological InvolvementRecruitingNCT06923072Phase 2
- A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder CancerRecruitingNCT06919965Phase 3
- Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06)Not yet recruitingNCT06919848Phase 2
- Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway AberrationsRecruitingNCT06915753Phase 1
- Tamoxifen for Advanced Solid Pseudopapillary Tumor of the PancreasRecruitingNCT06914674Phase 2
- An Exploratory Study to Evaluate the Efficacy and Safety of FCN-159 in Patients With Brain Arteriovenous MalformationsRecruitingNCT06913725Phase 2
- Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCCRecruitingNCT06912087Phase 1
- Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously TreatedRecruitingNCT06908993Phase 3
- Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer PatientsNot yet recruitingNCT06908772Phase 2/3
- A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic AlterationsRecruitingNCT06906562Phase 2
- Efficacy and Safety of Sintilimab Combined With Lenvatinib and HAIC for Neoadjuvant Therapy of Borderline Resectable HCCRecruitingNCT06904014Phase 2
- Efficacy and Safety of Upatinib in the Treatment of Active Anal Fistulas in Crohn's DiseaseRecruitingNCT06902987Phase 1
- XL092 and Cemiplimab in BRAF WT Thyroid CancerRecruitingNCT06902376Phase 1
- Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL PatientsNot yet recruitingNCT06901999Phase 2
- Camrelizumab and Chemotherapy With or Without Anlotinib as First-line Treatment for Advanced Gallbladder Cancer and Extrahepatic CholangiocarcinomaEnrolling by invitationNCT06901622Phase 2
- A Mass Balance Study of [14C]ABSK011Not yet recruitingNCT06896760Phase 1
- 9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)RecruitingNCT06896188Phase 1
- Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1)RecruitingNCT06895733Phase 1/2
- Individualized Comprehensive Treatment for Advanced Hepatocellular CarcinomaRecruitingNCT06893887Not applicable
- Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial TranscriptomicsNot yet recruitingNCT06893354Phase 4
- A Clinical Study on Fasudil Hydrochloride for Treatment of Gene-Specific Ovarian CancerRecruitingNCT06890858Phase 2
- Phase III Trial of Camrelizumab+Apatinib+Eribulin vs. Physician's Choice Chemotherapy in Advanced Triple-Negative Breast CancerRecruitingNCT06889688Phase 3
- SABR Combined with Axitinib and Toripalimab in Recurrent or Metastatic RCCRecruitingNCT06889649Phase 2
- Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)RecruitingNCT06889168Phase 1
- Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric CancerNot yet recruitingNCT06888037Phase 2
- A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK InhibitorsRecruitingNCT06887803Phase 1/2
- 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal CancerRecruitingNCT06887218Phase 2
- Study with Norucholic Acid Tablets in Patients with Primary Sclerosing Cholangitis (PSC)Not yet recruitingNCT06886360Phase 3
- An Exploratory Clinical Study on Neoadjuvant Treatment of Hepatocellular Carcinoma with QL1706 Combined with LenvatinibNot yet recruitingNCT06884982Phase 2
- Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard TherapyNot yet recruitingNCT06884748Early Phase 1
- Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular SubtypingNot yet recruitingNCT06881017Phase 2
- STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular CarcinomaRecruitingNCT06880523Phase 2
- A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin LymphomaRecruitingNCT06876662Phase 4
- A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) PirtobrutinibRecruitingNCT06876649Phase 4
- A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132RecruitingNCT06875960Phase 4
- A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia AreataRecruitingNCT06873945Phase 3
- Efficacy, Safety and Immunological Evaluation of Upadacitinib for Relapsing PolychondritisRecruitingNCT06873100Phase 1/2
- An Interventional Study of Infigratinib in Children With HypochondroplasiaEnrolling by invitationNCT06873035Phase 2/3
- Allo HSCT for High Risk HemoglobinopathiesRecruitingNCT06872333Phase 2
- Fruquintinib Combined With PD-1 Inhibitor and FOLFOX as First-Line Treatment For Advanced Gastric CancerNot yet recruitingNCT06871527Phase 1/2
- A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic ArthritisRecruitingNCT06869551Phase 3
- A Trial of Baricitinib in Patients With Cardiac SarcoidosisNot yet recruitingNCT06868381Phase 2
- Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic UrticariaRecruitingNCT06865651Phase 2
- A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative ColitisRecruitingNCT06865417Phase 3
- Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLCRecruitingNCT06864624Phase 2
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HS-10561 Capsule in Healthy Chinese Adults and Patients With Chronic Spontaneous Urticaria.Not yet recruitingNCT06864507Phase 1/2
- Phase II Clinical Study of Befotertinib in EGFR Non-classical Mutant NSCLCRecruitingNCT06863506Phase 2
- Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma SubtypeRecruitingNCT06863402Phase 2
- Therapeutic Effect of Upadacitinib in Primary Sjögren's SyndromeNot yet recruitingNCT06862284Phase 2
- A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid CarcinomaRecruitingNCT06860971Phase 3
- Cryoablation Combined With Lenvatinib Plus Tislelizumab Compared With FOLFOX in Patients With Advanced Intrahepatic Cholangiocarcinoma (CASTLE-ZS-01)RecruitingNCT06860477Phase 2
- Clinical Trial of TQB3702 Tablets in Subjects With Systemic Lupus Erythematosus (SLE)Not yet recruitingNCT06859931Phase 2
- Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)RecruitingNCT06859684Phase 2
- Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin LymphomaRecruitingNCT06859008Phase 1
- Lorlatinib Compared with Concurrent/ Sequential Chemoradiotherapy in Stage III ALK Positive Lung AdenocarcinomaNot yet recruitingNCT06858410Phase 3
- - IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver MetastasesRecruitingNCT06856837Phase 2
- A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast CancerRecruitingNCT06856200Not applicable
- Newly-diagnosed Pediatric T-cell ALL ProtocolRecruitingNCT06855810Phase 2/3
- Rollover Study for Participants Previously Enrolled in Clinical Trials of PovorcitinibRecruitingNCT06855498Phase 3
- GAPP Induction and Concurrent Chemoradiotherapy Followed by Toripalimab Maintenance for Nasopharyngeal Carcinoma.RecruitingNCT06851247Phase 2
- Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast CancerNot yet recruitingNCT06849947Phase 2
- Baricitinib in the Treatment of Intestinal Behçet's SyndromeRecruitingNCT06849908Phase 2
- Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLLRecruitingNCT06849713Phase 2
- HIM Typing Guides the Treatment of Advanced First-Line Triple-Negative Breast CancerNot yet recruitingNCT06849492Phase 2
- Antimicrobial Effect of Curcumin Versus Chlorohexidine on Oral MicrobiomeNot yet recruitingNCT06847984Not applicable
- A Study of Momelotinib in Participants With Low-risk Myelodysplastic SyndromeRecruitingNCT06847867Phase 2
- Acalabrutinib Plus Rituximab for the Treatment of Elderly or Low- to Intermediate-Risk Younger Untreated Mantle Cell LymphomaRecruitingNCT06846489Phase 2
- Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+RecruitingNCT06846463Phase 2
- Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.RecruitingNCT06846281Phase 3
- A Study of Mirdametinib in Combination With Palbociclib in People With LiposarcomaRecruitingNCT06843967Phase 1/2
- Sirolimus for Leigh SyndromeEnrolling by invitationNCT06843811Phase 2
- PD-L1 Inhibitor + RT ± Ursodeoxycholic Acid in Recurrent/Metastatic HER2-Neg Breast CancerNot yet recruitingNCT06842472Phase 2
- A Study of TYRA-300 in Children With Achondroplasia: BEACH301RecruitingNCT06842355Phase 2
- Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell LymphomaRecruitingNCT06839053Phase 2
- Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic CarcinomaRecruitingNCT06838910Phase 2
- A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC)RecruitingNCT06835972Phase 1/2
- EVR and EPO for Liver Transplant ToleranceRecruitingNCT06832189Phase 1