Partially Engineered T-regulatory Cell Donor Graft TRGFT-201 clinical trials
How each study uses Partially Engineered T-regulatory Cell Donor Graft TRGFT-201 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
6 studies that test it; most in 2022 (2)
| Year | Studies |
|---|---|
| 2019 | 1 |
| 2022 | 2 |
| 2024 | 1 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 3 · Other 3
Orca Biosystems, Inc. (3) · Melody Smith (1) · Stanford University (1) · City of Hope Medical Center (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 2
Studies that test Partially Engineered T-regulatory Cell Donor Graft TRGFT-201.
- Dec 2026Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCTPhase 1 · Stanford University
- Nov 2027Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromePhase 2 · Orca Biosystems, Inc.
Studies
Open first, then newest update. How each study uses Partially Engineered T-regulatory Cell Donor Graft TRGFT-201 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 6
- Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeRecruitingPhase 2Orca Biosystems, Inc.NCT07216443Written as Orca-T
- Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCTRecruitingPhase 1Stanford UniversityNCT06551584Written as ORCA-T
- Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic SyndromeSuspendedPhase 1City of Hope Medical CenterNCT06195891Written as Partially Engineered T-regulatory Cell Donor Graft TRGFT-201
- Myeloablative Conditioning Orca-T & Allogeneic Donor-Derived CD19/CD22-CAR TCells in B-Cell ALLActive, not recruitingPhase 1Melody SmithNCT05507827Written as Treg CD34+HSPC (Orca-T)
- Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesActive, not recruitingPhase 1Orca Biosystems, Inc.NCT04013685Written as Orca-T
- Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesActive, not recruitingPhase 3Orca Biosystems, Inc.NCT05316701Written as Orca-T
What changed recently
From the registry's own updates since Oct 14, 2026.