Nirogacestat: all 25 studies that test it
Page 1 of 1. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.
- Nirogacestat in Patients With Kaposi SarcomaRecruitingNCT07539454Phase 2
- Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)RecruitingNCT07176689Phase 4
- Study of Cryoablation and Nirogacestat for Desmoid TumorRecruitingNCT05949099Phase 2
- Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical StudyRecruitingNCT05879146Phase 2
- A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple MyelomaRecruitingNCT05573802Phase 1/2
- Sub-study of Belantamab Mafodotin (GSK2857916) as Monotherapy and in Combination With Nirogacestat, Pomalidomide, and Dexamethasone in Participants With RRMMActive, not recruitingNCT07150104Phase 1/2Results posted
- Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat, Lenalidomide, and Dexamethasone in Participants With RRMMActive, not recruitingNCT07150091Phase 1/2Results posted
- Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMMActive, not recruitingNCT07084896Phase 1/2Results posted
- Nirogacestat in Ovarian Granulosa Cell TumorsCompletedNCT05348356Phase 2Results posted
- MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple MyelomaTerminatedNCT05090566Phase 2Results posted
- Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)CompletedNCT03785964Phase 3Results posted
- A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch AlterationsTerminatedNCT02299635Phase 2Results posted
- Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer TherapiesTerminatedNCT02109445Phase 2Results posted
- Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive FibromatosisCompletedNCT01981551Phase 2Results posted
- A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast CancerTerminatedNCT01876251Phase 1Results posted
- A Trial In Patients With Advanced Cancer And LeukemiaCompletedNCT00878189Phase 1Results posted
- Evaluate the Effects of Famotidine or Rabeprazole on the PK of NirogacestatCompletedNCT07171619Phase 1
- A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)Active, not recruitingNCT07170644Phase 2
- A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After TreatmentActive, not recruitingNCT05556798Phase 1
- A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by SurgeryActive, not recruitingNCT04195399Phase 2
- A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple MyelomaTerminatedNCT04171843Phase 1
- Safety and Efficacy of ALLO-715 BCMA Allogenic CAR T Cells in in Adults With Relapsed or Refractory Multiple Myeloma (UNIVERSAL)CompletedNCT04093596Phase 1
- A Study Of PF-03084014 In Japanese Patients With Advanced Solid TumorsWithdrawnNCT02462707Phase 1
- Biomarker Research Study for PF-03084014 in cHEmoresistant Triple-negative Breast cAncerWithdrawnNCT02338531Phase 2
- Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi SarcomaWithdrawnNCT02137564Phase 2