MK4646 clinical trials
Also written MK-4646.
- studies test it
- 4
- open now
- 0
- in phase 3
- 0
- first study started
- 2025
How each study uses MK4646 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Development codes
- MK-4646
- 4
Studies by the year they started
4 studies that test it; most in 2025 (2)
| Year | Studies |
|---|---|
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 4
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 4 · Other 0
Often tested with
Tested in the same studies.
Bictegravir (1) · Emtricitabine (1) · Tenofovir alafenamide (1) · Dolutegravir (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test MK4646.
- Nov 2026A Clinical Trial to Evaluate the Effects of MK-4646 on Rosuvastatin in Healthy Participants (MK-4646-007)Phase 1 · Merck Sharp & Dohme LLC
Studies
Open first, then newest update. How each study uses MK4646 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 4
- A Clinical Trial to Evaluate the Effects of MK-4646 on Rosuvastatin in Healthy Participants (MK-4646-007)Active, not recruitingPhase 1Merck Sharp & Dohme LLCNCT07785830Written as MK-4646
- A Clinical Trial of MK-4646 With Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir in Healthy Adult Participants (MK-4646)CompletedPhase 1Merck Sharp & Dohme LLCNCT07532304Written as MK4646
- MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT07042945Written as MK-4646
- A Study of Rifabutin and MK-4646 in Healthy Participants (MK-4646-004)CompletedPhase 1Merck Sharp & Dohme LLCNCT07199452Written as MK-4646