Metreleptin: all 23 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Open-label Extension Study to Evaluate Metreleptin in Patients With Partial LipodystrophyRecruitingNCT06679270Phase 3
• Open-label Study to Evaluate Metreleptin in Patients With Partial LipodystrophyRecruitingNCT06484868Phase 4
• Evaluation of Safety and Efficiency of Metreleptin Treatment for Patients With Multiple Symmetric Lipomatosis (MSL)Active, not recruitingNCT05351164Phase 2Results posted
• Immunogenicity of Metreleptin in Patients With Generalized LipodystrophyCompletedNCT04026178Phase 4Results posted
• CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial LipodystrophyCompletedNCT02654977Phase 2Results posted
• Short-term Effects of Leptin in People With LipodystrophyCompletedNCT01778556Phase 2Results posted
• Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With LipodystrophyCompletedNCT01679197Phase 2Results posted
• Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy SyndromeCompletedNCT01511016Not applicableResults posted
• A Study To Examine The Efficacy And Safety Of Pramlintide+Metreleptin In Obese SubjectsTerminatedNCT01235741Phase 2Results posted
• Extension Study of Protocol DFA102 to Examine the Long-Term Safety, Tolerability, and Effect on Body Weight of Pramlintide Administered in Combination With MetreleptinCompletedNCT00819234Phase 2Results posted
• Study to Examine Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight SubjectsCompletedNCT00673387Phase 2Results posted
• Recombinant Leptin Therapy for Treatment of Nonalcoholic Steatohepatitis (NASH)CompletedNCT00596934Phase 2Results posted
• A Study to Evaluate the Effect on Body Weight of Leptin Administered in Conjunction With Pramlintide in Overweight and Obese SubjectsCompletedNCT00392925Phase 2Results posted
• Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic SyndromeCompletedNCT00140244Phase 2Results posted
• Role of Leptin in the Neuroendocrine and Immune Response to FastingCompletedNCT00140231Phase 1/2Results posted
• Pharmacokinetics of Leptin Administration During FastingCompletedNCT00140205Phase 1Results posted
• Study of Leptin for the Treatment of Hypothalamic AmenorrheaCompletedNCT00130117Phase 2Results posted
• Effect of Metreleptin Therapy in the Treatment of Severe Insulin ResistanceActive, not recruitingNCT00085982Phase 2Results posted
• Leptin to Treat LipodystrophyCompletedNCT00025883Phase 2Results posted
• Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised LipodystrophyTerminatedNCT06502990Phase 3
• Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PLActive, not recruitingNCT05164341Phase 3
• Compassionate Use of Metreleptin in Previously Treated People With Generalized LipodystrophyActive, not recruitingNCT02262832Phase 3
• Compassionate Use of Metreleptin in Previously Treated People With Partial LipodystrophyActive, not recruitingNCT02262806Phase 2

← Metreleptin overview