Lubiprostone: all 46 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal CancerNot yet recruitingNCT07405736Phase 2
• Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit ConstipationRecruitingNCT07277907Phase 3
• Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to PlaceboCompletedNCT03097861Phase 3Results posted
• Comparative Pharmacokinetics and Food-Effect Bioavailability of Lubiprostone Sprinkle in Healthy VolunteersCompletedNCT03010631Phase 3Results posted
• Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional ConstipationCompletedNCT02766777Phase 3Results posted
• Lubiprostone for Chronic Idiopathic Constipation TreatmentCompletedNCT02729909Phase 3Results posted
• Lubiprostone for Treatment of Chronic Idiopathic ConstipationCompletedNCT02695719Phase 3Results posted
• Lubiprostone for the Treatment of Chronic Idiopathic ConstipationCompletedNCT02651155Phase 3Results posted
• Evaluation of the Efficacy and Safety of Lubiprostone in Adults With Mixed or Unsubtyped Irritable Bowel SyndromeTerminatedNCT02544152Phase 2Results posted
• Lubiprostone for Children With ConstipationCompletedNCT02138136Phase 3Results posted
• Lubiprostone in Children With Functional ConstipationCompletedNCT02042183Phase 3Results posted
• Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic ConstipationCompletedNCT01993875Phase 3Results posted
• Lubiprostone as a Modulator of Gut Microbial Translocation in HIV With Incomplete CD4 Recovery on Antiretroviral TherapyCompletedNCT01839734Phase 2Results posted
• Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic ConstipationCompletedNCT01469819Phase 2/3Results posted
• Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic ConstipationCompletedNCT01460225Phase 4Results posted
• Lubiprostone and Mucus Secretion in Patients With Chronic ConstipationCompletedNCT01447849Phase 2/3Results posted
• Opioid-induced Bowel Dysfunction (OBD) Pivotal Assessment of Lubiprostone (OPAL)CompletedNCT01298219Phase 3Results posted
• Lubiprostone in Patients With Multiple Sclerosis Associated ConstipationCompletedNCT01236534Phase 4Results posted
• Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.CompletedNCT01190020Phase 1Results posted
• The Effectiveness of Lubiprostone in Constipated DiabeticsCompletedNCT01170039Phase 4Results posted
• Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With ConstipationCompletedNCT01162863Not applicableResults posted
• Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating MedicationsTerminatedNCT01096290Phase 4Results posted
• Effect of Lubiprostone on Small Bowel Contractions in Female Patients With Constipation Irritable Bowel Syndrome (C-IBS)CompletedNCT01085643Not applicableResults posted
• Lubiprostone, Colonic Motility and SensationCompletedNCT00953043Phase 4Results posted
• A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to ColonoscopyCompletedNCT00953017Phase 4Results posted
• Amitiza in Constipation Associated With PD (Parkinson's Disease)CompletedNCT00908076Phase 4Results posted
• Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut TransitCompletedNCT00844831Phase 4Results posted
• Randomized, Placebo-controlled Trial of Lubiprostone as a Preparation for Capsule EndoscopyCompletedNCT00746395Phase 4Results posted
• Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic FibrosisCompletedNCT00706004Not applicableResults posted
• Efficacy of Lubiprostone in Combination With Standard PEG PreparationTerminatedNCT00689026Not applicableResults posted
• Lubiprostone as a Treatment for Constipation in Parkinson's DiseaseTerminatedNCT00669461Not applicableResults posted
• Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient RehabilitationCompletedNCT00662363Not applicableResults posted
• Amitiza® Plus GoLYTELY® (PEG) Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy PreparationCompletedNCT00645801Phase 4Results posted
• Opioid-induced Bowel Dysfunction: Long-Term Assessment of LubiprostoneCompletedNCT00620061Phase 3Results posted
• Split Dose Golytely With Amitiza Pretreatment Versus Split Dose Golytely Plus Placebo in Outpatient ColonoscopyCompletedNCT00611442Not applicableResults posted
• Opioid-induced Bowel Dysfunction Pivotal Assessment of LubiprostoneCompletedNCT00597428Phase 3Results posted
• Opioid-induced Bowel Dysfunction: Pivotal Assessment of LubiprostoneCompletedNCT00595946Phase 3Results posted
• Safety and Efficacy of Lubiprostone in Pediatric Patients With ConstipationCompletedNCT00452335Phase 4Results posted
• Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With ConstipationCompletedNCT00399542Phase 3Results posted
• Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With ConstipationCompletedNCT00380250Phase 3Results posted
• Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver DiseaseCompletedNCT05768334Phase 3
• Evaluation of Clinical Equivalence Between Two Lubiprostone Products in the Treatment of Chronic Idiopathic ConstipationCompletedNCT01674530Phase 3
• Evaluation of Clinical Equivalence Between Two Lubiprostone ProductsCompletedNCT01372423Phase 3
• Comparative Study of Lubiprostone and PEG Preparation Versus Conventional PEG Preparation for ColonoscopyCompletedNCT01324284Phase 3
• Lubiprostone Effects on Visceral Pain SensitivityCompletedNCT01166789Phase 1
• Intestinal Microecology in Chronic ConstipationCompletedNCT00934479Phase 1

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