Interleukin 1 Receptor Antagonist Protein: all 169 studies that test it
Page 1 of 2. Open to participants first (26), then studies with results posted, then the rest; newest registration first within each.
- Anakinra for Prevention of Poor Graft Function in MDS Allo-HSCTNot yet recruitingNCT07888348Phase 1/2
- Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or OlderNot yet recruitingNCT07838974Phase 1
- Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA)Not yet recruitingNCT07600190Phase 1
- Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal DiseaseNot yet recruitingNCT07580079Phase 2
- "IL-1β Blockade to Prevent Immunothrombosis in Recipients of a Pancreatic Organ"RecruitingNCT07503834Phase 1/2
- Advancing Reperfusion Therapy for Ischemic Stroke: Safety and Efficacy of Anakinra for Futile Reperfusion Following Endovascular Treatment in Patients With Acute Ischemic StrokeRecruitingNCT07423975Phase 2
- BRIDGE - Blocking Receptor of IL-1β for Donor Graft Edema ReductionNot yet recruitingNCT07410312Early Phase 1
- ANAKINRA IN THE TREATMENT OF PEDIATRIC ACUTE MYOCARDITISNot yet recruitingNCT07371689Phase 3
- Anakinra Pilot 2 - A Study to Optimise Dose and Route of Administration of Anakinra in Preterm InfantsRecruitingNCT07254000Phase 2
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 2
- Non Inferiority KawasakI Trial With AnakinraNot yet recruitingNCT06697431Phase 4
- Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human EndotoxemiaRecruitingNCT06624436Phase 4
- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket TrialRecruitingNCT06381661Phase 2
- Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily TherapyRecruitingNCT06336733Phase 3
- Therapy Management in Patients Treated With Anakinra Due to Recurrent PericarditisRecruitingNCT06071156Not applicable
- Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid SyndromeRecruitingNCT05926505Phase 2/3
- Efficacy and Safety of Anakinra in Acute Respiratory Distress SyndromeRecruitingNCT05914454Phase 2
- Therapeutic Approach in Colchicine-resistant Recurrent pEricarditis in ChildrenNot yet recruitingNCT05805930Phase 3
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODSRecruitingNCT05267821Phase 2/3
- Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)RecruitingNCT04926467Phase 2
- Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic StrokeRecruitingNCT04834388Phase 2
- A Trial Comparing the Efficacy and Safety of Anakinra Versus Intravenous Immunoglobulin (IVIG) Retreatment, in Patients With Kawasaki Disease Who Failed to Respond to Initial Standard IVIG TreatmentRecruitingNCT04656184Phase 3
- Randomised Evaluation of COVID-19 TherapyRecruitingNCT04381936Phase 3
- Biologic Therapy to Prevent Osteoarthritis After ACL InjuryRecruitingNCT03968913Early Phase 1
- Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear DiseaseRecruitingNCT03587701Phase 2
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
- The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact DermatitisCompletedNCT05498467Phase 3Results posted
- MIS-C Comparative Effectiveness StudyCompletedNCT04898231Phase 2/3Results posted
- Pilot Study of Atorvastatin and Anakinra in Children With Coronary Artery Abnormalities Secondary to Kawasaki DiseaseCompletedNCT04747847Early Phase 1Results posted
- Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell LymphomaCompletedNCT04432506Phase 2Results posted
- Early Treatment of Cytokine Storm Syndrome in Covid-19CompletedNCT04362111Phase 3Results posted
- Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell TherapyCompletedNCT04359784Phase 2Results posted
- CORIMUNO-ANA: Trial Evaluating Efficacy Of Anakinra In Patients With Covid-19 InfectionCompletedNCT04341584Phase 2Results posted
- Treatment of COVID-19 Patients With Anti-interleukin DrugsCompletedNCT04330638Phase 3Results posted
- Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection.TerminatedNCT04324021Phase 2/3Results posted
- A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated NeurotoxicityCompletedNCT04150913Phase 2Results posted
- Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic HepatitisCompletedNCT04072822Phase 2Results posted
- Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisCompletedNCT04025554Phase 1/2Results posted
- Interleukin-1 Blockade for Treatment of Cardiac SarcoidosisCompletedNCT04017936Phase 2Results posted
- Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2CompletedNCT03797001Phase 2Results posted
- Study Evaluating the Safety and Efficacy of JCARH125 in Subjects With Relapsed and/or Refractory Multiple MyelomaCompletedNCT03430011Phase 1/2Results posted
- A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Still's Disease (SJIA and AOSD)TerminatedNCT03265132Phase 3Results posted
- Treatment of Acute Pericarditis With AnakinraTerminatedNCT03224585Phase 2Results posted
- Anti-Cytokine Therapy for Hemodialysis InflammatIONCompletedNCT03141983Phase 2Results posted
- A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty ArthritisCompletedNCT03002974Phase 2Results posted
- IL-1RA Treatment in Patients With Acute ACL Tear and Painful EffusionsTerminatedNCT02930122Phase 2Results posted
- Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist DevicesCompletedNCT02547766Phase 1/2Results posted
- Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple MyelomaCompletedNCT02492750Phase 1Results posted
- Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing LossTerminatedNCT02414152Phase 1/2Results posted
- Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2CompletedNCT02278562Phase 2Results posted
- Anakinra in Infants and Children With Coronary Artery Abnormalities in Acute Kawasaki DiseaseCompletedNCT02179853Phase 1/2Results posted
- Interleukin-1 Blockade in HF With Preserved EFCompletedNCT02173548Phase 2Results posted
- Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3)CompletedNCT01950299Phase 2/3Results posted
- Interleukin-1 Blockade in Recently Decompensated Heart FailureCompletedNCT01936909Phase 2/3Results posted
- Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF)CompletedNCT01936844Phase 2/3Results posted
- Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic HepatitisCompletedNCT01809132Phase 2/3Results posted
- Anakinra for Inflammatory Pustular Skin DiseasesCompletedNCT01794117Phase 2Results posted
- Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection FractionCompletedNCT01542502Not applicableResults posted
- Anakinra as a Treatment for Hydradenitis SuppurativaCompletedNCT01516749Phase 2Results posted
- Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Pulmonary HypertensionTerminatedNCT01479010Phase 1/2Results posted
- Immunomodulation, IL-1 Inhibition, and Postoperative Incisional PainTerminatedNCT01466764Not applicableResults posted
- Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1/2Results posted
- Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Heart FailureCompletedNCT01300650Phase 1/2Results posted
- A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear DiseaseCompletedNCT01267994Phase 1/2Results posted
- Anakinra to Prevent Adverse Post-infarction Remodeling (2)CompletedNCT01175018Phase 2Results posted
- Topical IL-1-Ra for Treatment of Corneal NeovascularizationTerminatedNCT00915590Phase 1/2Results posted
- Anakinra to Prevent Post-infarction RemodelingCompletedNCT00789724Phase 3Results posted
- Topical IL-1-Ra for Treatment of Posterior BlepharitisCompletedNCT00681109Phase 1/2Results posted
- Anti-inflammatory Therapy With Anakinra in Newly Diagnosed Type 1 DiabetesCompletedNCT00645840Phase 1/2Results posted
- Anakinra With or Without Dexamethasone in Treating Patients With Smoldering or Indolent Multiple MyelomaCompletedNCT00635154Phase 2Results posted
- Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis PatientsCompletedNCT00420290Not applicableResults posted
- Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory DiseaseTerminatedNCT00069329Phase 1/2Results posted
- An Efficacy and Safety Study of Subcutaneous Anakinra in Chinese Patients With Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still's Disease (AOSD)WithdrawnNCT07706868Phase 4
- IL-1 Inhibition in Early TNBCWithdrawnNCT06710197Phase 2
- Pre-emptive Anakinra for Cytokine Event ReductionWithdrawnNCT06703216Phase 1/2
- A Study to Evaluate Efficacy and Safety of Anakinra in Chinese Patients With Colchicine-resistent FMFWithdrawnNCT06666335Phase 4
- The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)CompletedNCT06062966Phase 1
- Hyperinsulinemia in Prediabetes Mediated by Interleukin-1βCompletedNCT05854251Phase 2
- A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)Active, not recruitingNCT05814159Phase 3
- Use of Presepsin as a Marker for Immunotherapy Administration in PneumoniaCompletedNCT05785442Phase 2
- Anakinra in Dengue With Hyperinflammation ( AnaDen )Active, not recruitingNCT05611710Phase 2
- Anakinra for Preterm Infants PilotActive, not recruitingNCT05280340Phase 1/2
- Combination of Inhaled DNase, Baricitinib and Tocilizumab in Severe COVID-19Status unknownNCT05279391Not applicable
- Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart FailureActive, not recruitingNCT05177822Phase 2
- Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With PrediabetesWithdrawnNCT05174507Phase 2
- Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain ExperienceStatus unknownNCT05074485Phase 1
- Dupilumab_Metastatic NSCLCActive, not recruitingNCT05013450Phase 1/2
- Personalized Immunotherapy in SepsisCompletedNCT04990232Phase 2
- Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal TransplantationSuspendedNCT04844814Phase 2
- Anakinra in Previously Untreated Chronic Lymphocytic Leukemia PatientsStatus unknownNCT04691765Phase 1
- suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19CompletedNCT04680949Phase 3
- Anakinra in the Management of COVID-19 InfectionCompletedNCT04643678Phase 2/3
- Anakinra, COVID-19, Cytokine StormWithdrawnNCT04603742Phase 2
- SCIL-1Ra in COVID-19 Feasibility & PK/PDTerminatedNCT04462757Phase 2
- Clinical Trial of the Use of Anakinra in Cytokine Storm Syndrome Secondary to Covid-19 (ANA-COVID-GEAS)CompletedNCT04443881Phase 2/3
- A Trial Using ANAKINRA, TOCILIZUMAB Alone or in Association With RUXOLITINIB in Severe Stage 2b and 3 of COVID19-associated DiseaseStatus unknownNCT04424056Phase 3
- Efficacy of Intravenous Anakinra and Ruxolitinib During COVID-19 InflammationTerminatedNCT04366232Phase 2
- suPAR-guided Anakinra Treatment for Validation of the Risk and Management of Respiratory Failure by COVID-19 (SAVE)CompletedNCT04357366Phase 2
- Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ DysfunctionCompletedNCT04339712Phase 2
- IL-1-receptor Antagonist During Cephalic Phase of Insulin Secretion in Health and Type 2 DiabetesTerminatedNCT04227769Phase 2