Immune Checkpoint Inhibitors: all 8,320 studies that test it
Page 3 of 84. Open to participants first (2,741), then studies with results posted, then the rest; newest registration first within each.
- A Trial of SHR-8068 Combined With Adebrelimab and Apatinib in Perioperative Treatment of Resectable Hepatocellular CarcinomaNot yet recruitingNCT07682272Phase 2
- Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System DiseaseNot yet recruitingNCT07681297Phase 1/2
- Phase 2 Study of Pembrolizumab and Lenvatinib in Anal Squamous Cell CancerNot yet recruitingNCT07680088Phase 2
- Safety and Efficacy of Nivolumab and Imiquimod Combination in Vulvar Squamous Cell Carcinoma PatientsNot yet recruitingNCT07679841Phase 1/2
- A Study of Trastuzumab Rezetecan in Combination With Adebrelimab Versus Investigator's Choice of Therapy in Subjects With Residual Triple Negative Breast CancerRecruitingNCT07679360Phase 3
- NIMBLE-CRC: NeoImmunoModulation Before Leveraging Excision in Colorectal Rectal CancerNot yet recruitingNCT07677579Phase 2
- A Study of ELI-002 7P, With or Without Tislelizumab, in People With Pancreatic CancerRecruitingNCT07671339Phase 1
- Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract CancerRecruitingNCT07670273Phase 2
- Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term ProgressionRecruitingNCT07670026Phase 2
- A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung CancerRecruitingNCT07669779Phase 2
- A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)RecruitingNCT07669220Phase 2
- SBRT Plus QL1706 as Second-Line Therapy for Hepatocellular CarcinomaNot yet recruitingNCT07668570Phase 4
- An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract MalignanciesRecruitingNCT07668453Phase 2
- Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial CancerRecruitingNCT07667335Phase 1/2
- Neoadjuvant EGFR-ADC Combined With Anti-PD-1 Monoclonal Antibody in Resectable Locally Advanced Hypopharyngeal Squamous Cell CarcinomaRecruitingNCT07665190Phase 2
- NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain TumorsRecruitingNCT07664176Phase 1
- Iparomlimab and Tovorilimab (QL1706) Combined With Bevacizumab and Chemotherapy as Neoadjuvant Therapy for Advanced Ovarian CancerNot yet recruitingNCT07663513Phase 2
- SYHX2011 in Combination With Carboplatin and Enlonstobart as First-Line Therapy for Squamous Non-Small Cell Lung CancerNot yet recruitingNCT07662811Phase 2/3
- Camrelizumab With Famitinib for Patients With Rare Head and Neck MalignanciesRecruitingNCT07662681Phase 1/2
- Aglatimagene Besadenovec + Prodrug and Pembrolizumab vs Docetaxel for Stage IV Non-Squamous NSCLC Progressing on Pembrolizumab (AURORA)RecruitingNCT07660094Phase 3
- Gotistobart Long Term Extension (LTE) StudyEnrolling by invitationNCT07659379Phase 3
- Sintilimab Plus Gossypol Acetate in Advanced Colorectal CancerNot yet recruitingNCT07656766Phase 2
- Mannatide Combined With CAPOX and Tislelizumab for Advanced Gastric Cancer.Not yet recruitingNCT07655661Phase 2
- Pilot Study of Ivonescimab in Advanced/Metastatic Cutaneous AngiosarcomaRecruitingNCT07655570Phase 2
- A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung CancerRecruitingNCT07654400Phase 2
- Neoadjuvant Lymph Node Targeted Immunotherapy in Cervical Cancer: a Feasibility Study (NEOLYNC)RecruitingNCT07653503Phase 1
- Precision Medicine for Immunotherapy-Resistant Advanced Esophageal CancerNot yet recruitingNCT07653451Phase 2/3
- A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Primary Advanced or Recurrent Endometrial CancerNot yet recruitingNCT07652515Phase 4
- OVV-01 Intravenous and Intratumoral Injection Combined With AK112 for the Treatment of Advanced Solid TumorsNot yet recruitingNCT07650825Phase 1
- Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase IINot yet recruitingNCT07649980Phase 2
- QL1706 Combined With Standard Therapy for Conversion Therapy of Synchronous Liver Metastases From Colon Cancer: a Multicenter, Single-arm, Exploratory StudyNot yet recruitingNCT07649473Phase 2
- EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBCRecruitingNCT07647289Phase 2
- A Prospective, Multicenter, Randomized Controlled Study on the Efficacy and Safety of Low-dose Carboplatin Combined With Nab-Paclitaxel and Delayed Administration of Serplulimab as First-line Treatment for Advanced Squamous Non-small Cell Lung CancerRecruitingNCT07647094Phase 2
- Trastuzumab Deruxtecan Plus ivonescImab for Hormone Receptor-positive HER2 Negative Advanced Breast Cancer StudyRecruitingNCT07647016Phase 2
- SSGJ-705 Plus SSGJ-612 ± Chemotherapy in Advanced HER2-Expressing Solid TumorsRecruitingNCT07646626Phase 2
- Exploratory Study on Toripalimab and Anlotinib Combined With Standard Chemotherapy for Refractory Dermatofibrosarcoma ProtuberansNot yet recruitingNCT07646080Phase 2
- Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal CancerNot yet recruitingNCT07645118Phase 2
- Thymosin Alpha 1 Combined With Anti-PD-1 Monoclonal Antibody in Elderly Patients With Advanced MelanomaRecruitingNCT07644897Phase 2
- Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPGNot yet recruitingNCT07644312Phase 2
- Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction AdenocarcinomaRecruitingNCT07643623Phase 2/3
- Efficacy and Safety of Induction Benmelstobart Plus Anlotinib and Chemotherapy Followed by Concurrent Chemoradiotherapy and Benmelstobart Maintenance Versus Concurrent Chemoradiotherapy Followed by Benmelstobart Maintenance in Patients With Unresectable Stage III NSCLCNot yet recruitingNCT07643350Phase 2
- Multi-Omics-Based Phase Ⅱ Trial of Trastuzumab Rezetecan Plus Camrelizumab for Perioperative Therapy in HER2-Positive Muscle-Invasive Urothelial CarcinomaNot yet recruitingNCT07639983Phase 2
- Ipilimumab (N01) Plus Sintilimab and Modified XELOX as Conversion Therapy in Unresectable Locally Advanced Gastric CancerNot yet recruitingNCT07638631Phase 2
- Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07638436Phase 2
- A Phase II Study of AK146D1 Mono or Combined With AK112 in Advanced Urothelial CarcinomaNot yet recruitingNCT07636772Phase 2
- QL1706 Plus Anlotinib as a Later-line Treatment for Patients With Advanced Lung CancerNot yet recruitingNCT07636226Phase 2/3
- Sitagliptin With Pembro in RCC and MelanomaRecruitingNCT07634380Phase 1
- SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for Patients With PD-L1-Positive Locally Advanced or Metastatic NSCLC（SYNSTAR 04）Not yet recruitingNCT07633873Phase 3
- A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cisplatin Versus Pembrolizumab and Gemcitabine/Cisplatin in Patients With CK5/6-High Unresectable Locally Advanced or Metastatic Intrahepatic CholangiocarcinomaNot yet recruitingNCT07632235Phase 1/2
- Axelopran and Nivolumab in PD-1-Refractory Metastatic MelanomaRecruitingNCT07631325Phase 1/2
- A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction CancerRecruitingNCT07631000Phase 2
- Trastuzumab Rezetecan(SHR-A1811) Combined With Ivonescimab (AK112) in Locally Advanced or Metastatic Non-small Cell Lung Cancer Harboring HER2 Gene AbnormalitiesNot yet recruitingNCT07630077Phase 2
- Study of Peripheral Neuropathy in Patients With Advanced Urothelial Cancer Treated With Enfortumab Vedotin and Pembrolizumab With Supportive Neuridase (ENDEAVOR)Not yet recruitingNCT07629700Not applicable
- Camrelizumab Combined With Famitinib Malate and Chemotherapy for Treatment of Recurrent/ Metastatic Cervical CancerNot yet recruitingNCT07627620Phase 2
- Anlotinib + Benmelstobart vs Surgery for Patients With Localized Renal Cell Carcinoma Scheduled to Undergo Partial NephrectomyNot yet recruitingNCT07627464Phase 2
- Becotatug Vedotin Combined With Pucotenlimab ± Radiotherapy as First-Line Treatment for Driver-Gene-Negative, EGFR-Expression-Positive Advanced Non-Small Cell Lung CancerNot yet recruitingNCT07627321Phase 2
- BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)RecruitingNCT07625644Phase 3
- A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Non-Small Cell Lung CancerRecruitingNCT07623356Phase 1/2
- A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal CanceNot yet recruitingNCT07622550Phase 2
- HIPEC Priming Followed by Serplulimab Plus SOX/XELOX in Locally Advanced Gastric CancerRecruitingNCT07621484Phase 2
- Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored StudyEnrolling by invitationNCT07620574Phase 3
- Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent GlioblastomasNot yet recruitingNCT07620548Phase 2
- A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving PembrolizumabRecruitingNCT07619599Phase 1
- A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung CancerRecruitingNCT07619339Phase 1
- A Study to Evaluate the PK Similarity of AK104 in Healthy Chinese Male ParticipationsNot yet recruitingNCT07619001Phase 1
- BRIDGE Study: Neoadjuvant Finotonlimab, Cetuximab, and Docetaxel in Resectable Recurrent HNSCC After Immunotherapy ProgressionEnrolling by invitationNCT07618624Phase 2
- A Multicenter, Randomized, Open-label, Controlled Study of HAIC Combined With Camrelizumab and Apatinib Mesylate for Perioperative Treatment of Resectable Hepatocellular Carcinoma With High-risk Recurrence FactorsNot yet recruitingNCT07618546Not applicable
- Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell DiseaseRecruitingNCT07616154Phase 2
- Adebrelimab Combined With SHR2554 in Relapsed/Refractory PTCL and NK/T-Cell LymphomaNot yet recruitingNCT07615283Phase 1/2
- Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 in Combination With Ivonescimab in Sq-NSCLC PatientsNot yet recruitingNCT07614646Phase 1
- Preoperative Radiotherapy and Anlotinib With or Without Penpulimab for Soft Tissue SarcomaNot yet recruitingNCT07612098Phase 2
- Gut Microbiota Modulation for Immunotherapy Resensitization in Advanced Renal Cell CarcinomaRecruitingNCT07611825Phase 2
- Blood and imagE-guided Optimization of Neoadjuvant Therapy in People With Early Stage Triple-negative Breast cancER - the BETTER TrialNot yet recruitingNCT07610525Phase 2
- A Study in People With Advanced Cancer to Test How Well Different Doses of BI 3819026 Are Tolerated When Taken Alone and Together With EzabenlimabRecruitingNCT07607678Phase 1
- A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for Early Relapse Colorectal Cancer After Adjuvant ChemotherapyRecruitingNCT07604909Phase 2
- A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)RecruitingNCT07602855Phase 1/2
- Neoadjuvant PD-L1 Inhibitor Plus Anlotinib for Kidney Preservation in Complex Renal Cell CarcinomaNot yet recruitingNCT07602101Phase 2
- Partial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsRecruitingNCT07599176Phase 1/2
- Serplulimab Monotherapy in Elderly Patients With NSCLC and PD-L1 TPS ≥ 50%RecruitingNCT07596121Phase 2
- Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3RecruitingNCT07595874Phase 2
- Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair DeficiencyNot yet recruitingNCT07595523Phase 2
- NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic CancerRecruitingNCT07595172Phase 1/2
- Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical TrialRecruitingNCT07594925Phase 2
- A Study of Ivonescimab in People With Non-Small Cell Lung CancerRecruitingNCT07594522Phase 1/2
- REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell CarcinomaRecruitingNCT07594106Phase 1/2
- Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Progression on or Following First-Line Immunotherapy MaintenanceRecruitingNCT07594015Phase 2
- A Multicenter, Phase Ib/II Clinical Trial to Evaluate the Efficacy and Safety of Concurrent Combination Therapy of S-531011 Plus Fruquintinib or S-531011 Plus Fruquintinib Plus Pembrolizumab in Patients With MSS/pMMR Colorectal CancerNot yet recruitingNCT07591597Phase 1/2
- A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast CancerRecruitingNCT07591090Phase 2
- AMT-116 in Combination With AK112 in Patients With Lung CancerRecruitingNCT07590531Phase 1/2
- RAIRI Model-Guided Adjuvant Therapy in Nasopharyngeal CarcinomaRecruitingNCT07590024Phase 3
- Becotatug Vedotin Combined With Pucotenlimab as Neoadjuvant Therapy for Resectable Recurrent Head and Neck Squamous Cell Carcinoma After Progression on Immunotherapy: A Prospective Phase II StudyNot yet recruitingNCT07589049Phase 2
- SKB118 Injection in Advanced Solid TumorsRecruitingNCT07586943Phase 1/2
- The DoHAICs Study Expansion PhaseNot yet recruitingNCT07584018Phase 2
- Low-dose Thoracic Radiotherapy Followed by Adebrelimab Plus Chemotherapy, and Then Sequential Maintenance Therapy With Adebrelimab for Extensive-stage Small Cell Lung CancerRecruitingNCT07583550Phase 2
- Efficacy and Safety of Immune Checkpoint Inhibitors for Refractory Opportunistic Infections in AIDSNot yet recruitingNCT07579247Phase 1/2
- Ph1/2 Trial Of Navlimetostat With Pumitamig In MTAP-Deficient Advanced Non-Small Cell Lung CancerRecruitingNCT07579221Phase 1/2
- Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial CancerNot yet recruitingNCT07578649Phase 3
- Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO TrialNot yet recruitingNCT07576725Phase 2
- A Phase II Study of Sintilimab, Pegaspargase and Selinexor Followed by Radiotherapy in Newly Diagnosed Stage I/II Extranodal NK/T-Cell LymphomaNot yet recruitingNCT07574528Phase 2
- MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.RecruitingNCT07574047Phase 2