DrugBiological
Idursulfase clinical trials
Also written Elaprase.
- studies test it
- 12
- open now
- 0
- in phase 3
- 7
- first study started
- 2003
How studies write it
Studies that test it under each name
Brand
Other names
Studies by the year they started
12 studies that test it; most in 2015 (2)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 1 |
| 2007 | 1 |
| 2010 | 1 |
| 2014 | 1 |
| 2015 | 2 |
| 2017 | 1 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 7
- Phase 3
- 7
- Phase 4
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 12 · Other 0
Shire (6) · Takeda (4) · Denali Therapeutics Inc. (1) · Green Cross Corporation (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses idursulfase is read from its arms, and is right about nine times in ten.
Testing it · 12
- A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)Active, not recruitingPhase 2/3Denali Therapeutics Inc.NCT05371613Written as idursulfase
- Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of AgeCompletedPhase 4ShireNCT02455622Written as Elaprase for intravenous (IV) infusion
- A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)WithdrawnPhase 4TakedaNCT05494593Written as ELAPRASE
- Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive ImpairmentActive, not recruitingPhase 2/3TakedaNCT06031259Written as Idursulfase-IT
- An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive ImpairmentCompletedPhase 1/2TakedaNCT01506141Written as Idursulfase-IT
- Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094CompletedPhase 2/3ShireNCT02412787Written as Idursulfase-IT
- A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in IndiaCompletedPhase 4TakedaNCT05058391Written as Elaprase
- A Study of GC1111 in Hunter Syndrom PatientsCompletedPhase 3Green Cross CorporationNCT03920540Written as GC1111
- Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive ImpairmentCompletedPhase 2/3ShireNCT02055118Written as idursulfase-IT
- Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)CompletedPhase 2/3ShireNCT00069641Written as Iduronate-2-sulfatase enzyme replacement therapy
- Extension of Study TKT024 Evaluating Long-Term Safety and Clinical Outcomes in MPS II Patients Receiving IdursulfaseCompletedPhase 2/3ShireNCT00630747Written as Idursulfase
- Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase TherapyCompletedPhase 4ShireNCT00607386Written as Idursulfase
As the comparator · 2 — what is tested is compared with idursulfase
- A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)Active, not recruitingPhase 3JCR Pharmaceuticals Co., Ltd.NCT04573023Written as Idursulfase
- Study of Idursulfase-beta (GC1111) in Hunter SyndromeStatus unknownPhase 2Green Cross CorporationNCT02663024Written as idursulfase
Codes
What other systems call idursulfase · ClinicalTrials.gg INT005050
- MeSH (NLM) C517982idursulfaseOne source ClinicalTrials.gov
- UNII (FDA) 5W8JGG2651IDURSULFASEConfirmed FDA, Wikidata
- RxNorm 644101Confirmed FDA, Wikidata
- Wikidata Q415801idursulfaseConfirmed FDA, Wikidata
- NCI Thesaurus C65883IdursulfaseOne source FDA
- DrugBank DB01271One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C517982 | idursulfase | One source ClinicalTrials.gov |
| UNII (FDA) | 5W8JGG2651 | IDURSULFASE | Confirmed FDA, Wikidata |
| RxNorm | 644101 | — | Confirmed FDA, Wikidata |
| Wikidata | Q415801 | idursulfase | Confirmed FDA, Wikidata |
| NCI Thesaurus | C65883 | Idursulfase | One source FDA |
| DrugBank | DB01271 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.