Colesevelam: all 52 studies that test it

Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.

• Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans StudyNot yet recruitingNCT07592858Phase 2
• Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)RecruitingNCT07226440Phase 1/2
• Metabolic Effects of Endogenous Bile Acids After Gastric Bypass SurgeryRecruitingNCT06925997Early Phase 1
• Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation.Not yet recruitingNCT06197763Phase 1/2
• Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)CompletedNCT03561883Phase 3Results posted
• A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)TerminatedNCT03561090Phase 3Results posted
• Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid MalabsorptionCompletedNCT03270085Phase 2Results posted
• A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)CompletedNCT02637557Phase 2Results posted
• A Study of Colesevelam in Fecal IncontinenceCompletedNCT02628626Phase 3Results posted
• Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCTTerminatedNCT02619812Phase 2Results posted
• Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile AcidsCompletedNCT02111603Phase 4Results posted
• Colesevelam for Children With Type 2 DiabetesCompletedNCT01258075Phase 4Results posted
• Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) ScaleCompletedNCT01122108Phase 4Results posted
• Colesevelam Versus Placebo in the Treatment of Nonalcoholic SteatohepatitisCompletedNCT01066364Phase 2Results posted
• Study to Evaluate the Effects of Colesevelam on Insulin Sensitivity and ß-Cell Function in Subjects With Impaired Fasting Glucose (Prediabetes)CompletedNCT00990184Phase 3Results posted
• The Effect of Welchol on Glucose Metabolism in Type 2 DiabeticsCompletedNCT00951899Phase 4Results posted
• Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?CompletedNCT00911612Phase 2Results posted
• Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes MellitusCompletedNCT00789750Phase 3Results posted
• Welchol as Monotherapy for Type 2 Diabetes MellitusCompletedNCT00789737Phase 3Results posted
• Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol MedicationCompletedNCT00715273Phase 4Results posted
• Mechanisms of Glucose Lowering Effect of Colesevelam HClCompletedNCT00596427Not applicableResults posted
• Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.CompletedNCT00570739Phase 3Results posted
• Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With MetforminCompletedNCT00484419Phase 3Results posted
• Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 DiabetesCompletedNCT00147745Phase 2Results posted
• Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High CholesterolCompletedNCT00145574Phase 4Results posted
• Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant NeratinibActive, not recruitingNCT05252988Phase 2
• Treatment of Bile Acid Malabsorption With LiraglutideCompletedNCT03955575Phase 4
• Effect of the Sequestrant Colesevelam in Bile Acid DiarrhoeaCompletedNCT03876717Phase 4
• Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult VolunteersCompletedNCT03856970Phase 1
• Bileacid Malabsorption and GLP-1 SecretionCompletedNCT03009916Phase 4
• Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric BypassCompletedNCT02952963Phase 4
• Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric BypassCompletedNCT02876484Phase 4
• Randomized Trial Comparing Colesevelam vs. EzetimibeCompletedNCT02682680Phase 4
• The Role of Metformin and Colesevelam in Human GLP-1 SecretionCompletedNCT02050074Phase 4
• Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump InhibitorsCompletedNCT02030925Phase 2
• Effects of Fish Oil and Colesevelam (STAIR7007)Status unknownNCT01948648Not applicable
• Effect of Bile Acids on GLP-1 SecretionCompletedNCT01666223Not applicable
• The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretionCompletedNCT01656057Not applicable
• Colesevelam Treatment for Impaired Fasting Glucose During Niacin TherapyCompletedNCT01239004Phase 4
• Colesevelam for the Treatment of Bile Acid Malabsorption in Patients With Crohn's DiseaseTerminatedNCT01203254Phase 4
• Efficacy of Colesevelam in Subjects With Type 1 Diabetes MellitusCompletedNCT00938405Not applicable
• Colesevelam Versus Placebo in Cholestatic PruritusCompletedNCT00756171Phase 2/3
• A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks.CompletedNCT00755352Phase 4
• Study to Compare Welchol and TriCor to TriCor Alone in Patients With High CholesterolCompletedNCT00754039Phase 4
• A Study to Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy VolunteersCompletedNCT00692250Phase 1
• A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing MedicationCompletedNCT00655265Phase 4
• Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes MellitusCompletedNCT00361153Phase 2
• Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High CholesterolCompletedNCT00185107Phase 4
• Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients With Type 2 DiabetesCompletedNCT00151762Phase 3
• WelChol® and Insulin in Treating Patients With Type 2 DiabetesCompletedNCT00151749Phase 3
• WelChol® and Sulfonylurea in Treating Patients With Type 2 DiabetesCompletedNCT00147758Phase 3
• WelChol® With Metformin in Treating Patients With Type 2 DiabetesCompletedNCT00147719Phase 3

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