Baxdrostat: all 28 studies that test it

Page 1 of 1. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Baxdrostat and Molecular Imaging of Adrenal Cytoreduction in Primary AldosteronismNot yet recruitingNCT07800858Not applicable
• A Phase IIIb Study to Investigate the Effect of Baxdrostat in Chinese Participants With Uncontrolled Hypertension.RecruitingNCT07686120Phase 3
• Baxdrostat and Ventricular RemodelingNot yet recruitingNCT07655362Phase 3
• A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood PressureRecruitingNCT06742723Phase 3
• Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinRecruitingNCT06677060Phase 3
• A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled HypertensionCompletedNCT06336356Phase 2Results posted
• A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant HypertensionCompletedNCT06168409Phase 3Results posted
• A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant HypertensionCompletedNCT06034743Phase 3Results posted
• Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124CompletedNCT05459688Phase 2Results posted
• A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney DiseaseCompletedNCT05432167Phase 2Results posted
• A Study of CIN-107 in Patients With Uncontrolled HypertensionCompletedNCT05137002Phase 2Results posted
• A Study of CIN-107 in Adults With Primary AldosteronismCompletedNCT04605549Phase 2Results posted
• A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)CompletedNCT04519658Phase 2Results posted
• A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.Active, not recruitingNCT07222917Phase 2
• Parent Study: A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism Sub-study: A Follow-up Substudy After Completion of the BaxPA Main Study.Active, not recruitingNCT07007793Phase 3
• A Study to Investigate the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel When Given Alone and in Combination With Baxdrostat in Healthy Females of Non-childbearing PotentialCompletedNCT06657105Phase 1
• A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy ParticipantsCompletedNCT06357520Phase 1
• A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant HypertensionCompletedNCT06344104Phase 3
• A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.Active, not recruitingNCT06268873Phase 3
• A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy ParticipantsCompletedNCT06194032Phase 1
• Baxdrostat Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Japanese PopulationCompletedNCT05966324Phase 1
• Baxdrostat Bioavailability and Bioequivalence StudyCompletedNCT05963009Phase 1
• Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic ImpairmentCompletedNCT05961397Phase 1
• Phase 1 Study to Determine the Metabolism and Clearance of BaxdrostatCompletedNCT05961384Phase 1
• Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy SubjectsCompletedNCT05526690Phase 1
• Study With CIN-107 Following Multiple Oral Ascending Doses in Healthy SubjectsCompletedNCT05500820Phase 1
• Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal FunctionCompletedNCT05470725Phase 1
• A Single Ascending Dose Study Investigating the Safety, Pharmacokinetics and Pharmacodynamics of RO6836191 in Healthy Male Volunteers.CompletedNCT01995383Phase 1

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