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Drug

Avapritinib clinical trials

Also written BLU-285 and AYVAKIT.

studies test it
18
open now
9
in phase 3
1
first study started
2015

How each study uses Avapritinib is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

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Approvals

The first approval found in each region, with its record

United States
9 Jan 2020 · AYVAKIT · NDA 212608 (FDA, Drugs@FDA)
European Union
24 Sept 2020 · Ayvakyt · EMEA/H/C/005208 (EMA)

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Avapritinib
16

Brand

AYVAKIT
4

Development codes

BLU-285
9
CS3007
1

Studies by the year they started

18 studies that test it; most in 2024 (4)

Studies that test Avapritinib, by start year
YearStudies
20151
20161
20182
20192
20201
20212
20223
20244
20252

By phase

A phase 1/2 study counts in both.

Phase 1
6
Phase 2
10
Phase 3
1
Phase 4
2
No phase
1

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Gastrointestinal Stromal Tumors
5
Leukemia, Myeloid, Acute
3
Mastocytosis, Systemic
2
Leukemia, Mast-Cell
2

Who runs them

Industry 10 · Other 8

Blueprint Medicines Corporation (9) · Institute of Hematology & Blood Diseases Hospital, China (2) · CStone Pharmaceuticals (1) · Ruijin Hospital (1) · Centre Leon Berard (1) · M.D. Anderson Cancer Center (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Children's Hospital of Soochow University (1)

Often tested with

Tested in the same studies.

Venetoclax (2) · Azacitidine (2) · Trametinib (2) · Midazolam (1) · Ivosidenib (1) · Gilteritinib (1) · Daunorubicin (1) · Cytarabine (1)

Related medicines

As reviewed, each with the page that says it.

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Reaching primary completion within a year · 4

Studies that test Avapritinib.

Studies

Open first, then newest update. How each study uses Avapritinib is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 18

Given beside what is tested · 1 — Avapritinib is usual care or a partner of the new treatment

Codes

What other systems call Avapritinib · ClinicalTrials.gg INT006892

  • MeSH (NLM) D000099289AvapritinibOne source NLM
  • UNII (FDA) 513P80B4YJAVAPRITINIBConfirmed FDA, NLM, Wikidata
  • RxNorm 2272107Confirmed FDA, Wikidata
  • Wikidata Q29213676avapritinibConfirmed FDA, NLM, Wikidata
  • NCI Thesaurus C123827AvapritinibOne source FDA
  • DrugBank DB15233One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.