Serotonin Syndrome clinical trials

The registry lists 35 studies for Serotonin Syndrome across more than 10 countries. 1 are recruiting or about to start. 20 of them are mainly about Serotonin Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-15.

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A study of drug A after surgery for early breast cancer

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· Enrollment: 300 → 450 participants

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Status

Completed: 18
Withdrawn: 5
Terminated: 5
Active, not recruiting: 3
Status unknown: 3
Not yet recruiting: 1

Phase

Phase 2: 14
Phase 3: 8
Phase 1: 2
Early Phase 1: 1
Phase 4: 1

Where

United States: 18
United Kingdom: 11
Germany: 7
France: 7
Poland: 6
Spain: 6

Who runs them

Lexicon Pharmaceuticals (6) · Ipsen (4) · M.D. Anderson Cancer Center (2) · Ciusss de L'Est de l'Île de Montréal (2) · Crinetics Pharmaceuticals Inc. (2) · Queen Mary University of London (1) · King's College Hospital NHS Trust (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1)

What is being tested here

Drugs under test in Serotonin Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Phase 3	All
Telotristat ethyl	4	8
Telotristat	4	8
Octreotide	0	3
Paltusotine	1	2
Amino Acid/Electrolyte Mixture-based Dietary Supplement	0	2
Cyproheptadine	1	2
Lanreotide	1	1
Octreotide hydrochloride	0	1
Octreotide Depot Formulation CAM2029	0	1
Pasireotide	0	1

Coming up

1phase 3 study under way

3studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3, phase 3 first

Aug 2027Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen · Phase 3 · Crinetics Pharmaceuticals Inc.
Dec 2026An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors · M.D. Anderson Cancer Center
Jun 2027CardioNETPOL National Registry of Carcinoid Heart Disease · National Institute of Cardiology, Warsaw, Poland

Who these studies take

No Serotonin Syndrome study is recruiting now.

Across all 35 studies, recruiting or not: 6% stop at 75 or younger and 3% at 65; 3% take children; 0% are for women only and 3% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 35 of 35. search them.