Hypopharyngeal Neoplasms: all 83 studies

Page 1 of 1. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.

• Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck CancersRecruitingNCT07857655Phase 4
• Thermotherapy for Head and Neck Cancer PatientsRecruitingNCT07690618Phase 1
• Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate CancerRecruitingNCT07667400Phase 1/2
• Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)Not yet recruitingNCT07552558Phase 1/2
• A Machine Learning-Based Risk Prediction Model for Head and Neck Cancerous LesionsRecruitingNCT07532538
• Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive CisplatinRecruitingNCT07441681Phase 3
• Neoadjuvant Chemotherapy Combined With Finotonlimab in the Treatment of Locally Advanced Hypopharyngeal CarcinomaRecruitingNCT07248956Phase 2
• Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell CarcinomaRecruitingNCT07156227Phase 1
• Neoadjuvant Treatment of Locally Advanced Hypopharyngeal Cancer With Adebrelimab Combined With TP Chemotherapy RegimenNot yet recruitingNCT07137039Phase 2
• A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)RecruitingNCT07063212Phase 2
• Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States PopulationRecruitingNCT06997068Phase 2
• Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck CancerRecruitingNCT06914999Early Phase 1
• TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell CancerRecruitingNCT06868433Phase 1
• Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck CarcinomaRecruitingNCT06706401Phase 3
• Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or RadiationRecruitingNCT06662058Not applicable
• Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP TrialRecruitingNCT06636734Phase 2
• Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous TreatmentRecruitingNCT06589804Phase 3
• Tislelizumab and Induction Chemotherapy for Larynx Preservation in Resectable Advanced Laryngeal/Hypopharyngeal CancerNot yet recruitingNCT06554028Phase 2
• Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck CancerRecruitingNCT06532279Phase 2
• Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal CancerRecruitingNCT06039631Phase 2
• The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal CancerRecruitingNCT05894070
• Efficacy and Safety of Toripalimab Combined With AP-induced Chemotherapy Followed in Non-metastatic IVB Hypopharyngeal CancerRecruitingNCT05860335Phase 2
• The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell CarcinomaRecruitingNCT05494190Not applicable
• Induction Chemotherapy and Toripalimab Followed by Radiotherapy in Unresectable Laryngeal/Hypopharyngeal CarcinomaRecruitingNCT05420597Phase 2
• Immune Biomarker Study for Head and Neck CancerRecruitingNCT05375266
• Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck CancerRecruitingNCT05172245Phase 1
• BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot StudyRecruitingNCT05136196Phase 2
• Clinical Treatments in Specialized Diseases of Laryngeal Carcinoma (LC) and Hypopharyngeal Carcinoma (HPC)RecruitingNCT04908696
• Toripalimab Plus TPF Chemotherapy and Radiotherapy for LA-HPSCCNot yet recruitingNCT04624308Phase 2
• Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 TrialRecruitingNCT04502641Phase 3
• Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)RecruitingNCT04198766Phase 1/2
• Neck Dissection vs Radiotherapy for Cervical Metastases in Advanced Hypopharyngeal CancerNot yet recruitingNCT03367884Not applicable
• Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck CancerRecruitingNCT03010150
• Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone SurgeryRecruitingNCT02734537Phase 2
• Integrated Cancer Repository for Cancer ResearchRecruitingNCT02012699
• Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and NeckRecruitingNCT01473784Not applicable
• Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"RecruitingNCT01365169Not applicable
• Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT00900419
• Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck CancerActive, not recruitingNCT04576091Phase 1Results posted
• Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal CancerCompletedNCT03894891Phase 2Results posted
• Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take CisplatinCompletedNCT03258554Phase 2/3Results posted
• Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell CarcinomaCompletedNCT03082534Phase 2Results posted
• Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck CancerCompletedNCT02589938Not applicableResults posted
• Pembrolizumab in Combination With CRT for LA-SCCHNCompletedNCT02586207Phase 1Results posted
• Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and NeckCompletedNCT02113878Phase 1Results posted
• 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis TherapyCompletedNCT01806675Phase 1/2Results posted
• Assessing the da Vinci® Robotic Surgical System for Surgery of the Upper Aerodigestive TractTerminatedNCT00721539Not applicableResults posted
• Robotic Assisted Surgery in Upper Aerodigestive Tract SurgeryCompletedNCT00473564Not applicableResults posted
• Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based TreatmentActive, not recruitingNCT07697287Phase 4
• Salvage Surgery in Recurrent Hypopharyngeal Carcinoma: an Observational Single-institutional Study From 1998Active, not recruitingNCT07295561
• Thermotherapy for Locally Advanced Head and Neck CancerActive, not recruitingNCT06761937Phase 1
• INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCCActive, not recruitingNCT06295731Phase 2/3
• Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck CancerWithdrawnNCT06084845Phase 2
• The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr SurvivorsCompletedNCT05798780Not applicable
• Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and NeckActive, not recruitingNCT05721755Phase 3
• Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and NeckActive, not recruitingNCT05172258Phase 2
• Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT StudyActive, not recruitingNCT05075980Phase 2
• Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck CancersActive, not recruitingNCT05063552Phase 2/3
• Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckActive, not recruitingNCT04862650Phase 2
• Benefit of Enhanced Contact Endoscopy in Pre-histological Diagnosis of Laryngeal and Hypopharyngeal Mucosal LesionsStatus unknownNCT04777474Not applicable
• Induction Chemotherapy Combined With Camrelizumab in Locoregionally Advanced Hypopharyngeal CancerStatus unknownNCT04539600Phase 2
• Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take CisplatinActive, not recruitingNCT04533750Phase 1
• Toripalimab in Combination With Chemotherapy as Induced Chemotherapy for Localized Hypopharyngeal CancerStatus unknownNCT04296747Phase 2
• Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer PatientsCompletedNCT03934294Not applicable
• New Strategy of Improving Treatment Outcome and Larynx-preservation Rate in Locally Advanced Hypopharyngeal CarcinomaStatus unknownNCT03558035Phase 2
• Interest of MRI in Preoperative Staging for the Laryngeal and Hypopharyngeal CancerCompletedNCT03132727
• A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic SurgeryCompletedNCT03010813Not applicable
• Definitive Chemo-Radiotherapy for Regionally Advanced Head and Neck Cancer With or Without Up-front Neck DissectionCompletedNCT02918955Phase 3
• Dose Escalation Versus Standard in Laryngopharyngeal CancersCompletedNCT02757222Not applicable
• A Post-Market Clinical Trial for Access and Visualization of the Oropharynx, Hypopharynx and Larynx During Transoral ProceduresCompletedNCT02262247
• Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer PatientsActive, not recruitingNCT02253238Not applicable
• Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx CancerStatus unknownNCT01516996Phase 2
• Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.CompletedNCT01469429Phase 1/2
• A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On CetuximabCompletedNCT01435252Phase 2
• Neoadjuvant Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN)CompletedNCT01312350Phase 2
• Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper Aerodigestive TractWithdrawnNCT01175499Not applicable
• Pharmacogenetic Response to Chemotherapy Induction for ORL CancersCompletedNCT01104714
• Effects of Swallowing Exercises on Patients Undergoing Radiation Treatment for Head and Neck CancerTerminatedNCT01053546Not applicable
• Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CACompletedNCT00534729Not applicable
• The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell CarcinomaStatus unknownNCT00302562
• The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell CarcinomaStatus unknownNCT00174096
• The Role of Lymphangiogenesis in Head and Neck Cancer MetastasisStatus unknownNCT00173381
• Very Intense Radiotherapy-chemotherapy Regimen in Advanced HNSCCCompletedNCT00162708Phase 2/3

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