Carcinoma, Large Cell clinical trials
The registry lists 20 studies for Carcinoma, Large Cell across more than 10 countries. 1 are recruiting or about to start. 2 of them are mainly about Carcinoma, Large Cell (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-16.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Maia Biotechnology (2) · Pfizer (2) · Ariad Pharmaceuticals (2) · Pharmacyclics LLC. (2) · Creative Biosciences (Guangzhou) Co., Ltd. (1) · Infinity Pharmaceuticals, Inc. (1) · NewLink Genetics Corporation (1) · M.D. Anderson Cancer Center (1)
What is being tested here
Drugs under test in Carcinoma, Large Cell studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Alpha-2'-deoxythioguanosine | 1 | 1 | 2 |
| Cemiplimab | 1 | 1 | 1 |
| Docetaxel | 0 | 0 | 2 |
| Figitumumab | 0 | 2 | 2 |
| Brigatinib | 0 | 1 | 1 |
| Albumin-Bound Paclitaxel | 0 | 0 | 1 |
| Paclitaxel | 0 | 0 | 1 |
| Carboplatin | 0 | 0 | 1 |
| Vandetanib | 0 | 1 | 1 |
| Everolimus | 0 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 3 · Antimitotic agents 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2, phase 3 first
- Jul 2027A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC · Phase 3 · Maia Biotechnology
- Sep 2027THIO Sequenced With Cemiplimab in Advanced NSCLC · Maia Biotechnology
Who these studies take
Of the 1 Carcinoma, Large Cell studies recruiting now, 1 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (100%) | 1 (100%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 1 (100%) | 1 (100%) |
| 85 | 1 (100%) | 1 (100%) |
Across all 20 studies, recruiting or not: 5% stop at 75 or younger and 5% at 65; 5% take children; 0% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 20 of 20. search them.
- A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLCRecruitingNCT06908304Phase 34 countries
- THIO Sequenced With Cemiplimab in Advanced NSCLCActive, not recruitingNCT05208944Phase 28 countries
- A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaCompletedNCT053371631 country
- ALTA-1L Study: A Study of Brigatinib Versus Crizotinib in Anaplastic Lymphoma Kinase Positive (ALK+) Advanced Non-small Cell Lung Cancer (NSCLC) ParticipantsCompletedNCT02737501Phase 319 countries
- Vaccine Treatment for Advanced Non-Small Cell Lung CancerCompletedNCT00073398Phase 1/21 country
- -02341066 and PF-00299804 for Advanced Non-Small Cell Lung CancerTerminatedNCT01441128Phase 11 country
- Safety and Efficacy Study of Abraxane in Combination With Carboplatin to Treat Advanced NSCL Cancer in the ElderlyCompletedNCT02151149Phase 41 country
- An Expanded Access Study of Brigatinib for Patients With ALK-positive Advanced Non-Small Cell Lung CancerNo longer availableNCT027841581 country
- Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)TerminatedNCT01511081Phase 21 country
- Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)TerminatedNCT00632203Phase 2
- ZD6474 (ZACTIMA™) Phase III Study in EGFR FailuresCompletedNCT00404924Phase 322 countries
- RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine DifferentiationCompletedNCT01317615Phase 41 country
- A Double-blind Study Evaluating IPI-504 and Docetaxel in Patients With Non-Small Cell Lung CancerCompletedNCT01362400Phase 26 countries
- Photodynamic Therapy (PDT) With Temoporfin for Non-Resectable Non-Small-Cell Lung CancerWithdrawnNCT01637376Phase 11 country
- Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma HistologyTerminatedNCT00596830Phase 326 countries
- Trial of Motexafin Gadolinium and Pemetrexed (Alimta®) for Second Line Treatment in Patients With Non-Small Cell Lung CancerTerminatedNCT00365183Phase 21 country
- Trial Of CP-751, 871 And Erlotinib In Refractory Lung CancerTerminatedNCT00673049Phase 327 countries
- A Phase II Clinical Trial of Docetaxel, Oxaliplatin Combination Chemotherapy in Patients With Stage IIIB/IV Non-adenocarcinoma, Non-small Cell Lung Cancer (NSCLC) as Second-line TreatmentStatus unknownNCT01497041Phase 21 country
- An Open Label Study of a Peptide Vaccine in Patients With Stage IIb or IIIa Non-Small Cell Lung CancerCompletedNCT00054899Phase 11 country
- A Study of Motexafin Gadolinium (MGd) in Combination With Docetaxel and Cisplatin for Treatment of Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00102505Phase 11 country